2015
Unlike adults, children and adolescents show predominantly increased neural activation to social exclusion by members of the opposite gender
Bolling DZ, Pelphrey KA, Vander Wyk B. Unlike adults, children and adolescents show predominantly increased neural activation to social exclusion by members of the opposite gender. Social Neuroscience 2015, 11: 475-486. PMID: 26592311, PMCID: PMC4976300, DOI: 10.1080/17470919.2015.1117019.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingNeural correlatesGroup membershipOnline ball-tossing gameSocial exclusionAnterior cingulate responsesBall-tossing gameSocial anxiety disorderOpposite genderSocio-emotional developmentDifferential neural correlatesAnterior cingulate cortexPrevious adult studiesPeer rejectionCingulate responseBrain responsesPeer relationsNeural activationAnxiety disordersCingulate cortexMain effectCurrent studyAdolescenceIncreased activationAdolescentsTrait-level temporal lobe hypoactivation to social exclusion in unaffected siblings of children and adolescents with autism spectrum disorders
Bolling DZ, Pelphrey KA, Wyk B. Trait-level temporal lobe hypoactivation to social exclusion in unaffected siblings of children and adolescents with autism spectrum disorders. Developmental Cognitive Neuroscience 2015, 13: 75-83. PMID: 26011751, PMCID: PMC4470300, DOI: 10.1016/j.dcn.2015.04.007.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderSpectrum disorderPosterior superior temporal sulcusUnaffected siblingsAtypical neural processingSocial exclusionFunctional magnetic resonance imagingSuperior temporal sulcusAbnormal neural responsesAnterior temporoparietal junctionAnterior cingulate cortexEmotion processingTemporoparietal junctionNegative affectTemporal sulcusNeural processingBrain responsesNeural endophenotypesNeural responsesNeural activationCingulate cortexNeural circuitrySocial experienceASD probandsPowerful feelings
2013
Social, reward, and attention brain networks are involved when online bids for joint attention are met with congruent versus incongruent responses
Gordon I, Eilbott JA, Feldman R, Pelphrey KA, Vander Wyk B. Social, reward, and attention brain networks are involved when online bids for joint attention are met with congruent versus incongruent responses. Social Neuroscience 2013, 8: 544-554. PMID: 24044427, DOI: 10.1080/17470919.2013.832374.Peer-Reviewed Original ResearchConceptsJoint attentionTemporoparietal junctionIncongruent responsesFMRI paradigmFunctional magnetic resonance imaging (fMRI) researchDorsal anterior cingulate cortexNaturalistic fMRI paradigmsHuman social functioningImpact of congruencySocial responsesRight temporoparietal junctionEye gaze patternsRight fusiform gyrusPosterior parietal cortexMagnetic resonance imaging researchAnterior cingulate cortexSocial neuroscienceIncongruent trialsAttention circuitsFusiform gyrusCongruent responsesNeural activationBrain networksRight amygdalaSocial functioningEquivalent neural responses in children and adolescents with and without autism during judgments of affect
Wyk B, Hoffman F, Pelphrey KA. Equivalent neural responses in children and adolescents with and without autism during judgments of affect. Developmental Cognitive Neuroscience 2013, 8: 121-130. PMID: 24016745, PMCID: PMC3931746, DOI: 10.1016/j.dcn.2013.08.001.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderCognitive loadNeural activationGreater cognitive loadFunction of taskFunctional connectivity analysisLonger stimulus durationsEmotion processingFMRI taskCondition contrastsNeural responsesSpectrum disorderStimulus durationBehavior measuresConnectivity analysisGroup differencesPrior researchPrevious researchEmotionsTaskChildrenValence levelsIQAutismIndividuals