Bone Lead Levels and Risk of Incident Primary Open-Angle Glaucoma: The VA Normative Aging Study
Wang W, Moroi S, Bakulski K, Mukherjee B, Weisskopf M, Schaumberg D, Sparrow D, Vokonas P, Hu H, Park S. Bone Lead Levels and Risk of Incident Primary Open-Angle Glaucoma: The VA Normative Aging Study. Environmental Health Perspectives 2018, 126: 087002. PMID: 30102601, PMCID: PMC6108844, DOI: 10.1289/ehp3442.Peer-Reviewed Original ResearchConceptsPrimary open-angle glaucomaIncident primary open-angle glaucomaRisk of primary open-angle glaucomaOpen-angle glaucomaHazard ratioIncident cases of POAGCases of primary open-angle glaucomaAsymmetric cup-to-disc ratioFollow-upPrimary open-angle glaucoma casesEtiology of primary open-angle glaucomaCup-to-disc ratioVisual field defectsCox proportional hazards regressionAssociated with hazard ratiosProportional hazards regressionOxidative stressEstimate hazard ratiosDisc hemorrhageOcular evaluationPatella leadField defectsCumulative lead doseProspective cohortSurvival curves