2022
ExPRSweb: An online repository with polygenic risk scores for common health-related exposures
Ma Y, Patil S, Zhou X, Mukherjee B, Fritsche L. ExPRSweb: An online repository with polygenic risk scores for common health-related exposures. American Journal Of Human Genetics 2022, 109: 1742-1760. PMID: 36152628, PMCID: PMC9606385, DOI: 10.1016/j.ajhg.2022.09.001.Peer-Reviewed Original ResearchConceptsPolygenic risk scoresChronic conditionsPhenome-wide association studyMichigan Genomics InitiativeRisk scoreAssociation studiesHealth-related exposuresGenome-wide association studiesUK BiobankGenetic risk factorsPRS methodsFollow-up studyRisk factorsComplex traitsGenome InitiativeGenetic modifiersBiobankInfluence of exposureEnvironmental variablesScoresLipid levelsExpRLifestyleSmokingOnline repository
2009
Case–Control Studies of Gene–Environment Interaction: Bayesian Design and Analysis
Mukherjee B, Ahn J, Gruber S, Ghosh M, Chatterjee N. Case–Control Studies of Gene–Environment Interaction: Bayesian Design and Analysis. Biometrics 2009, 66: 934-948. PMID: 19930190, PMCID: PMC3103064, DOI: 10.1111/j.1541-0420.2009.01357.x.Peer-Reviewed Original ResearchConceptsGene-environment interactionsCase-control study of colorectal cancerStudy of gene-environment interactionsStudy of colorectal cancerGene-environment independenceRed meat consumptionBayesian designCase-control studyBayesian approachSample size determination criteriaCase-controlEpidemiological studiesColorectal cancerFrequentist counterpartsNatural wayMeat consumptionAnalyze current dataHypothesis testingDetermination criteriaSmokingEpidemiological exposureAnalysis strategyStudy
2008
Association between 24-Hour Urinary Cadmium and Pulmonary Function among Community-Exposed Men: The VA Normative Aging Study
Lampe B, Park S, Robins T, Mukherjee B, Litonjua A, Amarasiriwardena C, Weisskopf M, Sparrow D, Hu H. Association between 24-Hour Urinary Cadmium and Pulmonary Function among Community-Exposed Men: The VA Normative Aging Study. Environmental Health Perspectives 2008, 116: 1226-1230. PMID: 18795167, PMCID: PMC2535626, DOI: 10.1289/ehp.11265.Peer-Reviewed Original ResearchConceptsSmoking statusCommunity-based study of agingAssessed effect modificationForced vital capacityPulmonary functionCommunity-based studyAssociated with forced expiratory volumeStudy of AgingFEV(1)/FVC ratioCadmium exposureUrinary cadmiumNormative Aging StudyEffect modificationEnvironmental cadmium exposureLevels of cadmium exposureAssociated with reduced pulmonary functionTests of pulmonary functionMixed-effects modelsAging StudyChronic cadmium exposureSmokingCadmium body burdenForced expiratory volumeCigarette smokingLog unit increase