Merit of quinacrine in the decrease of ingested sulfite-induced toxic action in rat brain
Kencebay C, Derin N, Ozsoy O, Kipmen-Korgun D, Tanriover G, Ozturk N, Basaranlar G, Yargicoglu-Akkiraz P, Sozen B, Agar A. Merit of quinacrine in the decrease of ingested sulfite-induced toxic action in rat brain. Food And Chemical Toxicology 2012, 52: 129-136. PMID: 23168241, DOI: 10.1016/j.fct.2012.11.015.Peer-Reviewed Original ResearchConceptsSomatosensory evoked potentialsSecretory phospholipase A2Quinacrine administrationS groupPlasma-S-sulfonate levelLatencies of SEP componentsMale albino Wistar ratsBrain TBARS levelsControl levelsTUNEL-positive cellsSQ groupTBARS levelsAlbino Wistar ratsSPLA2 levelsApoptotic cell deathGastric gavageSEP alterationsPositive cellsWistar ratsSEP componentsIntraperitoneal injectionRat brainCaspase-3RatsQuinacrine treatmentUltrastructural analysis of vascular features in cerebral cavernous malformations
Tanriover G, Sozen B, Seker A, Kilic T, Gunel M, Demir N. Ultrastructural analysis of vascular features in cerebral cavernous malformations. Clinical Neurology And Neurosurgery 2012, 115: 438-444. PMID: 22776801, DOI: 10.1016/j.clineuro.2012.06.023.Peer-Reviewed Original ResearchMeSH KeywordsApoptosis Regulatory ProteinsBlood VesselsBrainCarrier ProteinsCerebrovascular CirculationChromosome MappingEndothelium, VascularGene Expression RegulationHumansImmunohistochemistryIntracranial Arteriovenous MalformationsKRIT1 ProteinMembrane ProteinsMicroscopy, Electron, ScanningMicroscopy, Electron, TransmissionMicrotubule-Associated ProteinsNeurogliaPericytesPlatelet Endothelial Cell Adhesion Molecule-1Proto-Oncogene ProteinsStromal CellsConceptsCerebral cavernous malformationsVascular malformationsCavernous malformationsUltrastructural featuresBasal laminaIntact basal laminaHuman CCM lesionsConventional indicationsClinical behaviorThin vessel wallWeak immunostainingCCM lesionsVascular endotheliumPathogenic mechanismsLuminal endotheliumVascular featuresMalformationsEndothelial cellsEndotheliumVessel wallLesionsUltrastructural analysisIntercellular junctionsFirst studyRupture