2012
Ultrastructural analysis of vascular features in cerebral cavernous malformations
Tanriover G, Sozen B, Seker A, Kilic T, Gunel M, Demir N. Ultrastructural analysis of vascular features in cerebral cavernous malformations. Clinical Neurology And Neurosurgery 2012, 115: 438-444. PMID: 22776801, DOI: 10.1016/j.clineuro.2012.06.023.Peer-Reviewed Original ResearchMeSH KeywordsApoptosis Regulatory ProteinsBlood VesselsBrainCarrier ProteinsCerebrovascular CirculationChromosome MappingEndothelium, VascularGene Expression RegulationHumansImmunohistochemistryIntracranial Arteriovenous MalformationsKRIT1 ProteinMembrane ProteinsMicroscopy, Electron, ScanningMicroscopy, Electron, TransmissionMicrotubule-Associated ProteinsNeurogliaPericytesPlatelet Endothelial Cell Adhesion Molecule-1Proto-Oncogene ProteinsStromal CellsConceptsCerebral cavernous malformationsVascular malformationsCavernous malformationsUltrastructural featuresBasal laminaIntact basal laminaHuman CCM lesionsConventional indicationsClinical behaviorThin vessel wallWeak immunostainingCCM lesionsVascular endotheliumPathogenic mechanismsLuminal endotheliumVascular featuresMalformationsEndothelial cellsEndotheliumVessel wallLesionsUltrastructural analysisIntercellular junctionsFirst studyRupture
2011
CCM2 expression during prenatal development and adult human neocortex
Tanriover G, Sozen B, Gunel M, Demir N. CCM2 expression during prenatal development and adult human neocortex. International Journal Of Developmental Neuroscience 2011, 29: 509-514. PMID: 21569831, DOI: 10.1016/j.ijdevneu.2011.04.006.Peer-Reviewed Original ResearchConceptsAdult human neocortexCerebral cavernous malformationsHuman neocortexNeuroglial precursor cellsPrenatal developmentMeans of immunohistochemistryCentral nervous systemWestern blot analysisHuman brain developmentVascular malformationsAdult neocortexGlial cellsCavernous malformationsCCM lesionsVascular endotheliumNervous systemVascular channelsBlood vessel formationArterial endotheliumBrain developmentNeocortexExpression patternsEndotheliumPrecursor cellsCCM loci