Parathyroid hormone effects on signaling pathways in endothelial cells vary with peptide concentration
Throckmorton D, Kurscheid-Reich D, Rosales OR, Rodriguez-Commes J, Lopez R, Sumpio B, Zhong Q, Ding K, McCarthy R, Barrett PQ, Isales CM. Parathyroid hormone effects on signaling pathways in endothelial cells vary with peptide concentration. Peptides 2002, 23: 79-85. PMID: 11814621, DOI: 10.1016/s0196-9781(01)00582-4.Peer-Reviewed Original ResearchConceptsParathyroid hormoneEndothelial cell lineVoltage-sensitive calcium channelsParathyroid hormone effectsSensitive calcium channelsUmbilical vein endothelial cell lineHuman umbilical vein endothelial cell lineCell linesProtein kinase CCalcium channelsHormone effectsEndothelial cellsFurther studiesPhospholipid turnoverPeptide concentrationPKC translocationSpecific effectsKinase CCell homogenatesPKC isoformsParticulate fraction