Cyclic strain increases endothelial nitric oxide synthase activity.
Awolesi MA, Widmann MD, Sessa WC, Sumpio BE. Cyclic strain increases endothelial nitric oxide synthase activity. Surgery 1994, 116: 439-44; discussion 444-5. PMID: 7519368.Peer-Reviewed Original ResearchConceptsEndothelial nitric oxide synthaseRegulation of eNOSCultured bovine aortic endothelial cellsENOS activityAortic endothelial cellsEndothelial cellsBovine aortic endothelial cellsEndothelial nitric oxide synthase activityNitric oxideNitric oxide synthase activityOxide synthase activityNitric oxide synthaseNitric oxide productionHemodynamic forcesRelaxing factorsGreiss reactionCycles/minOxide synthaseENOS geneMedium of ECOxide productionCycles/minuteFunctional activityStrain regimensSynthase activity