Systemic and cell-specific mechanisms of vasculopathy induced by human immunodeficiency virus and highly active antiretroviral therapy
Haser GC, Sumpio B. Systemic and cell-specific mechanisms of vasculopathy induced by human immunodeficiency virus and highly active antiretroviral therapy. Journal Of Vascular Surgery 2016, 65: 849-859. PMID: 26994951, DOI: 10.1016/j.jvs.2016.01.036.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusActive antiretroviral therapySmooth muscle cellsAntiretroviral therapyHIV patientsImmunodeficiency virusTraditional cardiovascular risk factorsMuscle cellsEndothelial cellsCardiovascular risk factorsChronic immune activationSerious cardiovascular eventsDevelopment of atherosclerosisVascular systemCardiovascular eventsVascular complicationsHIV medicationsChronic inflammationImmune activationMyocardial infarctionRisk factorsCell-specific mechanismsGeneral populationCholesterol metabolismCardiovascular pathology