2004
Regulation of Interleukin-8 Expression in Human Endometrial Endothelial Cells: A Potential Mechanism for the Pathogenesis of Endometriosis
Luk J, Seval Y, Kayisli UA, Ulukus M, Ulukus CE, Arici A. Regulation of Interleukin-8 Expression in Human Endometrial Endothelial Cells: A Potential Mechanism for the Pathogenesis of Endometriosis. The Journal Of Clinical Endocrinology & Metabolism 2004, 90: 1805-1811. PMID: 15613411, DOI: 10.1210/jc.2004-1813.Peer-Reviewed Original ResearchConceptsHuman endometrial endothelial cellsIL-8 mRNAEndometrial endothelial cellsIL-8 expressionSex steroidsEndothelial cellsEutopic endometriumCultured human endometrial endothelial cellsIL-8 immunoreactivityEffects of estradiolEutopic endometrial tissuesPathogenesis of endometriosisInterleukin-8 expressionMenstrual cycle phaseEndothelium-specific markersEndometriosis implantsInflammatory basisCytokine levelsEndometriotic implantsInflammatory mediatorsChemokine expressionEndometrial tissueInflammatory aspectsIL-8Endometriosis
2003
Apoptosis and the Pathogenesis of Endometriosis
Garcia-Velasco J, Arici A. Apoptosis and the Pathogenesis of Endometriosis. Seminars In Reproductive Medicine 2003, 21: 165-172. PMID: 12917786, DOI: 10.1055/s-2003-41323.Peer-Reviewed Original ResearchConceptsPathogenesis of endometriosisEndometrial cellsSex steroid modulationDisease-free womenEutopic endometrial cellsBcl-2/BaxEndometriotic implantsSteroid modulationInflammatory environmentInflammatory reactionAbnormal survivalEndometriosisApoptosis-related genesFas ligandPhysiologic processesEarly eventsPathogenesisApoptosis
1996
The peritoneal environment in endometriosis
Oral E, Olive D, Arici A. The peritoneal environment in endometriosis. Human Reproduction Update 1996, 2: 385-398. PMID: 15717438, DOI: 10.1093/humupd/2.5.385.Peer-Reviewed Original ResearchConceptsPeritoneal fluidPeritoneal environmentPF of womenEtiology of endometriosisMonocytes/macrophagesSpermatozoon-oocyte interactionEndometriotic implantsEndometrial fragmentsPeritoneal factorsPeritoneal endometriosisRetrograde menstruationIL-8MCP-1Postimplantation survivalChemoattractant cytokinesMast cellsEndometriosisImmune systemMesothelial cellsCytokinesGrowth factorOvum captureMacrophagesEtiologyCell types