2019
Perihematomal Edema After Intracerebral Hemorrhage in Patients With Active Malignancy
Gusdon AM, Nyquist PA, Torres-Lopez VM, Leasure AC, Falcone GJ, Sheth KN, Sansing LH, Hanley DF, Malani R. Perihematomal Edema After Intracerebral Hemorrhage in Patients With Active Malignancy. Stroke 2019, 51: 129-136. PMID: 31744426, PMCID: PMC7048624, DOI: 10.1161/strokeaha.119.027085.Peer-Reviewed Original ResearchConceptsBlood product transfusionThirty-day mortalityIntracerebral hemorrhagePerihematomal edemaActive malignancyProduct transfusionPHE volumeICH volumeActive cancerPHE growthPlatelet transfusionsCentral nervous system involvementRecurrence of malignancyNervous system involvementNontraumatic intracerebral hemorrhageCancer-specific dataPHE expansionRecent chemotherapyChart reviewConclusions PatientsControl patientsMost patientsHematoma volumeInstitutional databaseSystem involvement
2016
Rate of Perihematomal Edema Expansion Predicts Outcome After Intracerebral Hemorrhage
Urday S, Beslow LA, Dai F, Zhang F, Battey TW, Vashkevich A, Ayres AM, Leasure AC, Selim MH, Simard JM, Rosand J, Kimberly WT, Sheth KN. Rate of Perihematomal Edema Expansion Predicts Outcome After Intracerebral Hemorrhage. Critical Care Medicine 2016, 44: 790-797. PMID: 26757167, PMCID: PMC4859217, DOI: 10.1097/ccm.0000000000001553.Peer-Reviewed Original ResearchConceptsRankin Scale scorePerihematomal edema volumeIntracerebral hemorrhageEdema volumePerihematomal edemaScale scoreOrdinal shift analysisPerihematomal edema expansionPatients 18 yearsRetrospective cohort studyTertiary medical centerIntracerebral Hemorrhage ScoreNeurologic outcomeCohort studyIndependent predictorsIntraventricular hemorrhageSecondary injuryWorse outcomesCurrent treatmentHemorrhage scoreMedical CenterCT scanDevastating disorderEdema expansionHemorrhageTreatment of Edema Associated With Intracerebral Hemorrhage
Leasure A, Kimberly WT, Sansing LH, Kahle KT, Kronenberg G, Kunte H, Simard JM, Sheth KN. Treatment of Edema Associated With Intracerebral Hemorrhage. Current Treatment Options In Neurology 2016, 18: 9. PMID: 26874842, DOI: 10.1007/s11940-015-0392-z.Peer-Reviewed Original ResearchPerihematomal edemaIntracerebral hemorrhageHypertonic salineFirst-line medical therapyTreatment of ICHWorse clinical outcomesLarge clinical trialsSubsequent continuous infusionTreatment of edemaEdema refractoryClinical deteriorationBrain herniationCommon complicationDecompressive craniectomyMedical therapyClinical outcomesContinuous infusionEdema formationClinical trialsBolus formClinical researchHemorrhageNext major advanceEdemaPilot study