2022
Non-linear associations between HPA axis activity during infancy and mental health difficulties during early childhood among children in rural Pakistan.
Frost A, Hagaman A, Baranov V, Chung EO, Bhalotra S, Sikander S, Maselko J. Non-linear associations between HPA axis activity during infancy and mental health difficulties during early childhood among children in rural Pakistan. Development And Psychopathology 2022, 35: 2086-2095. PMID: 35959681, PMCID: PMC9922341, DOI: 10.1017/s0954579422000773.Peer-Reviewed Original ResearchConceptsHPA axis activityMental health difficultiesAxis activityHealth difficultiesEarly childhoodHypothalamic pituitary adrenal axis activityPituitary-adrenal axis activitySDQ scoresAdrenal axis activityNon-linear associationLongitudinal cohortDepression trialsQuadratic associationHair cortisolDehydroepiandosteroneRural PakistanMental healthCortisolEarly adversitySignificant quadratic associationDifficulties QuestionnaireLow-resource contextsChildhoodChildrenAssociation
2020
Effectiveness of a peer-delivered, psychosocial intervention on maternal depression and child development at 3 years postnatal: a cluster randomised trial in Pakistan
Maselko J, Sikander S, Turner EL, Bates LM, Ahmad I, Atif N, Baranov V, Bhalotra S, Bibi A, Bibi T, Bilal S, Biroli P, Chung E, Gallis JA, Hagaman A, Jamil A, LeMasters K, O'Donnell K, Scherer E, Sharif M, Waqas A, Zaidi A, Zulfiqar S, Rahman A. Effectiveness of a peer-delivered, psychosocial intervention on maternal depression and child development at 3 years postnatal: a cluster randomised trial in Pakistan. The Lancet Psychiatry 2020, 7: 775-787. PMID: 32828167, PMCID: PMC8015797, DOI: 10.1016/s2215-0366(20)30258-3.Peer-Reviewed Original ResearchConceptsMaternal depressionPsychosocial interventionsUsual careLong-term maternal outcomesMaternal depression symptomsAllocation statusScalable psychosocial interventionsMaternal outcomesRandomisation sequencePrimary outcomePregnant womenExcess riskDepression exposureRecurring courseSevere symptomsTrial participantsOffspring outcomesDepression symptomsDepressionVillage clustersInterventionTrialsOutcomesSymptomsPrincipal investigatorThe contribution of grandmother involvement to child growth and development: an observational study in rural Pakistan
Chung EO, Hagaman A, LeMasters K, Andrabi N, Baranov V, Bates LM, Gallis JA, O'Donnell K, Rahman A, Sikander S, Turner EL, Maselko J. The contribution of grandmother involvement to child growth and development: an observational study in rural Pakistan. BMJ Global Health 2020, 5: e002181. PMID: 32784209, PMCID: PMC7418670, DOI: 10.1136/bmjgh-2019-002181.Peer-Reviewed Original Research
2019
Cohort Profile: Perinatal depression and child socioemotional development ; the Bachpan cohort study from rural Pakistan
Sikander S, Ahmad I, Bates LM, Gallis J, Hagaman A, O’Donnell K, Turner EL, Zaidi A, Rahman A, Maselko J. Cohort Profile: Perinatal depression and child socioemotional development ; the Bachpan cohort study from rural Pakistan. BMJ Open 2019, 9: e025644. PMID: 31061029, PMCID: PMC6502044, DOI: 10.1136/bmjopen-2018-025644.Peer-Reviewed Original ResearchConceptsSocioemotional developmentDetrimental developmental outcomesChildren's socioemotional developmentMother-child dyadsPerinatal depressionEffect of depressionSocioemotional measuresChild developmentDevelopmental outcomesPsychosocial measuresPoor child developmentPregnancy birth cohortChild's ageSchool environmentCohort studyInflammatory biomarkersChronic courseEligible dyadsPregnant womenRisk factorsBaseline assessmentRepeated measuresDyadsDepressionChildrenThe relationship between responsive caregiving and child outcomes: evidence from direct observations of mother-child dyads in Pakistan
Scherer E, Hagaman A, Chung E, Rahman A, O’Donnell K, Maselko J. The relationship between responsive caregiving and child outcomes: evidence from direct observations of mother-child dyads in Pakistan. BMC Public Health 2019, 19: 252. PMID: 30819173, PMCID: PMC6396475, DOI: 10.1186/s12889-019-6571-1.Peer-Reviewed Original ResearchConceptsChildren's socioemotional developmentResponsive caregivingSocioemotional developmentChild developmentCaregiving behaviorChild outcomesMother-child interaction measuresMaternal depressionChildren's socioemotional outcomesMother-child dyadsChild development outcomesHierarchical linear regressionSocioemotional outcomesChild's signalsChild behaviorHome ObservationHOME scoresPhysical outcomesCaregivingLongitudinal studyLower scoresChild's lifeBook activitiesCross-sectional associationsBaseline sociodemographic factors