Single-cell transcriptomics of the human placenta: inferring the cell communication network of the maternal-fetal interface
Pavličev M, Wagner GP, Chavan AR, Owens K, Maziarz J, Dunn-Fletcher C, Kallapur SG, Muglia L, Jones H. Single-cell transcriptomics of the human placenta: inferring the cell communication network of the maternal-fetal interface. Genome Research 2017, 27: 349-361. PMID: 28174237, PMCID: PMC5340963, DOI: 10.1101/gr.207597.116.Peer-Reviewed Original ResearchConceptsSingle-cell transcriptomicsG protein-coupled receptorsCell communication networksGene expression profilesReceptor-ligand pairsCell type identificationOrganismal functionInteraction hubTrophoblast cellsGene expressionExpression profilesEndometrial stromal fibroblastsSpecific expressionCell typesInteractomeTranscriptomicsRich resourceCell interactionsPlacental trophoblast cellsDecidual cellsImmune signalsStromal cellsGrowth factorStromal fibroblastsEndometrial stromal cells