2017
Single-cell transcriptomics of the human placenta: inferring the cell communication network of the maternal-fetal interface
Pavličev M, Wagner GP, Chavan AR, Owens K, Maziarz J, Dunn-Fletcher C, Kallapur SG, Muglia L, Jones H. Single-cell transcriptomics of the human placenta: inferring the cell communication network of the maternal-fetal interface. Genome Research 2017, 27: 349-361. PMID: 28174237, PMCID: PMC5340963, DOI: 10.1101/gr.207597.116.Peer-Reviewed Original ResearchConceptsSingle-cell transcriptomicsG protein-coupled receptorsCell communication networksGene expression profilesReceptor-ligand pairsCell type identificationOrganismal functionInteraction hubTrophoblast cellsGene expressionExpression profilesEndometrial stromal fibroblastsSpecific expressionCell typesInteractomeTranscriptomicsRich resourceCell interactionsPlacental trophoblast cellsDecidual cellsImmune signalsStromal cellsGrowth factorStromal fibroblastsEndometrial stromal cells
2016
The fetal-maternal interface of the nine-banded armadillo: endothelial cells of maternal sinus are partially replaced by trophoblast
Chavan AR, Wagner GP. The fetal-maternal interface of the nine-banded armadillo: endothelial cells of maternal sinus are partially replaced by trophoblast. Zoological Letters 2016, 2: 11. PMID: 27284459, PMCID: PMC4899922, DOI: 10.1186/s40851-016-0048-1.Peer-Reviewed Original ResearchMaternal immune systemImmune systemFetal-maternal immune toleranceSemi-allogenic fetusFetal-maternal interfaceVascular endothelial layerUterine connective tissuePresence of leukocytesEndometrial stromaImmune toleranceImmunohistochemical toolsIntervillous spaceUterine tissuePlacental fibrinoidTrophoblast cellsInvasive placentationEndothelial liningMaternal sinusesEndothelial cellsEndothelial layerSinusConnective tissueBlood sinusesMaternal tissuesLuminal side