Transfer of pathogenic and nonpathogenic cytosolic proteins between spinal cord motor neurons in vivo in chimeric mice
Thomas EV, Fenton WA, McGrath J, Horwich AL. Transfer of pathogenic and nonpathogenic cytosolic proteins between spinal cord motor neurons in vivo in chimeric mice. Proceedings Of The National Academy Of Sciences Of The United States Of America 2017, 114: e3139-e3148. PMID: 28348221, PMCID: PMC5393223, DOI: 10.1073/pnas.1701465114.Peer-Reviewed Original ResearchConceptsMotor neuronsChimeric miceSpinal cord motor neuronsCranial nerve motor nucleiDouble fluorescenceMammalian nervous systemMo of ageGray matter oligodendrocytesCytosolic proteinsExtraocular nucleiMotor nucleusSpinal cordNervous systemNeuronsMiceSuperoxide dismutase 1 proteinEight-cell embryosPathogenic proteinsOligodendrocytesDismutase 1 proteinThird chimeraChimeric progenyRecent studiesEGFP chimerasCells