2013
Integrin α3 Is Required for Late Postnatal Stability of Dendrite Arbors, Dendritic Spines and Synapses, and Mouse Behavior
Kerrisk ME, Greer CA, Koleske AJ. Integrin α3 Is Required for Late Postnatal Stability of Dendrite Arbors, Dendritic Spines and Synapses, and Mouse Behavior. Journal Of Neuroscience 2013, 33: 6742-6752. PMID: 23595732, PMCID: PMC3711182, DOI: 10.1523/jneurosci.0528-13.2013.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAlpha-FetoproteinsAnalysis of VarianceAnimalsAnimals, NewbornBasic Helix-Loop-Helix Transcription FactorsCell MembraneDendritesDendritic SpinesDisks Large Homolog 4 ProteinFemaleGene Expression Regulation, DevelopmentalGreen Fluorescent ProteinsGuanylate KinasesHippocampusImmunoprecipitationIntegrin alpha3LysineMaleMembrane ProteinsMemory DisordersMiceMice, Inbred C57BLMice, TransgenicModels, BiologicalNerve Tissue ProteinsNeuronsPhosphopyruvate HydrataseRecognition, PsychologyRhoA GTP-Binding ProteinSynapsesConceptsDendritic spinesIntegrin α3Adult rodent forebrainHippocampal-dependent behaviorsPostnatal day 21Excitatory forebrain neuronsMouse behaviorProper hippocampal functionLong-term potentiationArbor stabilityArg nonreceptor tyrosine kinaseRodent forebrainForebrain neuronsSynapse densitySynapse stabilityDendrite arborsDay 21Arbor sizeHippocampal dendritesHippocampal functionMutant miceSynapse maintenanceBrain functionNeurodegenerative diseasesKey mediator
2007
Defective T Cell Development and Function in the Absence of Abelson Kinases
Gu JJ, Zhang N, He YW, Koleske AJ, Pendergast AM. Defective T Cell Development and Function in the Absence of Abelson Kinases. The Journal Of Immunology 2007, 179: 7334-7343. PMID: 18025176, DOI: 10.4049/jimmunol.179.11.7334.Peer-Reviewed Original ResearchConceptsT cell developmentT cellsMutant miceCell-autonomous roleT cell-dependent AgCD8 T cellsListeria monocytogenes infectionT cell expansionCell developmentNumber of thymocytesT cell functionDouble-positive stageDouble-negative populationDefective T cell developmentConditional knockout miceT cells resultsNull T cellsTCR-induced signalingCytokine productionMonocytogenes infectionAb productionKnockout miceThymocyte proliferationConditional deletionMice