Lower urinary tract symptoms, benign prostatic hyperplasia, and obesity
Mongiu AK, McVary KT. Lower urinary tract symptoms, benign prostatic hyperplasia, and obesity. Current Urology Reports 2009, 10: 247-253. PMID: 19570484, DOI: 10.1007/s11934-009-0041-8.Peer-Reviewed Original ResearchConceptsLower urinary tract symptomsBenign prostatic hyperplasiaBPH/lower urinary tract symptomsUrinary tract symptomsLifestyle modificationTract symptomsProstatic hyperplasiaGlobal public health challengeParticular polymorphismsCommon neoplastic conditionPrevalence of obesityClinical trial methodologyPublic health challengeStrong independent relationshipProstate sizePhysical inactivityTrial methodologyNeoplastic conditionsEpidemiological studiesObesityHealth challengesIndependent relationshipIndividual treatmentHyperplasiaSymptomsVariation in Institutional Review Board Responses to a Standard Protocol for a Multicenter Randomized, Controlled Surgical Trial
Helfand BT, Mongiu AK, Roehrborn CG, Donnell RF, Bruskewitz R, Kaplan SA, Kusek JW, Coombs L, McVary KT, Investigators M. Variation in Institutional Review Board Responses to a Standard Protocol for a Multicenter Randomized, Controlled Surgical Trial. Journal Of Urology 2009, 181: 2674-2679. PMID: 19375101, PMCID: PMC4720253, DOI: 10.1016/j.juro.2009.02.032.Peer-Reviewed Original ResearchConceptsInstitutional review boardStudy protocolSurgical trialsReview boardMulticenter trialLocal institutional review board reviewIdentical study protocolMulticenter surgical trialInstitutional review board approvalInvasive surgical therapiesBenign prostatic hyperplasiaMulticenter clinical trialReview board approvalSurgical therapyMedical therapyMulticenter RandomizedSurgical interventionProstatic hyperplasiaClinical trialsBoard approvalInstitutional review board reviewTrialsType of responseSecond reviewTherapy