2011
Robo4 Maintains Vessel Integrity and Inhibits Angiogenesis by Interacting with UNC5B
Koch AW, Mathivet T, Larrivée B, Tong RK, Kowalski J, Pibouin-Fragner L, Bouvrée K, Stawicki S, Nicholes K, Rathore N, Scales SJ, Luis E, del Toro R, Freitas C, Bréant C, Michaud A, Corvol P, Thomas JL, Wu Y, Peale F, Watts RJ, Tessier-Lavigne M, Bagri A, Eichmann A. Robo4 Maintains Vessel Integrity and Inhibits Angiogenesis by Interacting with UNC5B. Developmental Cell 2011, 20: 33-46. PMID: 21238923, DOI: 10.1016/j.devcel.2010.12.001.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntibodies, BlockingBlood VesselsCapillary PermeabilityEnzyme ActivationHumansLigandsMiceModels, BiologicalNeovascularization, PathologicNerve Tissue ProteinsNetrin ReceptorsProtein BindingReceptors, Cell SurfaceReceptors, ImmunologicRetinal VesselsSignal TransductionSrc-Family KinasesSus scrofaVascular Endothelial Growth Factor AConceptsProtein-protein interaction screenVascular endothelial growth factorFunction-blocking monoclonal antibodiesInteraction screenNovel functionGuidance receptorsExtracellular domainNetrin receptorsReceptor familyVessel integrityReceptor interactionInhibits angiogenesisRobo4Unexpected interactionsGrowth factorEndothelial cellsUNC5BVascular integrityEndothelial growth factorAngiogenesisIncreases angiogenesisReceptorsMonoclonal antibodiesIntegrityProtein
2001
Hemangioblast Commitment in the Avian Allantois: Cellular and Molecular Aspects
Caprioli A, Minko K, Drevon C, Eichmann A, Dieterlen-Lièvre F, Jaffredo T. Hemangioblast Commitment in the Avian Allantois: Cellular and Molecular Aspects. Developmental Biology 2001, 238: 64-78. PMID: 11783994, DOI: 10.1006/dbio.2001.0362.Peer-Reviewed Original ResearchMeSH KeywordsAllantoisAnimalsCell LineageChick EmbryoCoturnixDNA-Binding ProteinsEndodermErythroid-Specific DNA-Binding FactorsGATA2 Transcription FactorGATA3 Transcription FactorHematopoietic Stem CellsImmunohistochemistryIn Situ HybridizationLeukocyte Common AntigensMesodermModels, BiologicalProto-Oncogene ProteinsReceptor Protein-Tyrosine KinasesReceptors, Growth FactorReceptors, Vascular Endothelial Growth FactorRNA, MessengerTime FactorsTrans-ActivatorsTranscription FactorsConceptsGATA-2Allantoic budCommitment of mesodermTranscription factor GATA-2SCL/talHemopoietic cellsHemangioblast commitmentEndoderm specificationOrgan formationGATA-1Definitive lineageStage HH17Blood islandsBlood island-like structuresEndodermMolecular processesMesodermEngrafted hostsMolecular aspectsHemopoietic lineagesGene patternsYolk sacBudsQuail embryosEmbryos
1998
Intraaortic hemopoietic cells are derived from endothelial cells during ontogeny
Jaffredo T, Gautier R, Eichmann A, Dieterlen-Lièvre F. Intraaortic hemopoietic cells are derived from endothelial cells during ontogeny. Development 1998, 125: 4575-4583. PMID: 9778515, DOI: 10.1242/dev.125.22.4575.Peer-Reviewed Original Research