A highly integrated and complex PPARGC1A transcription factor binding network in HepG2 cells
Charos AE, Reed BD, Raha D, Szekely AM, Weissman SM, Snyder M. A highly integrated and complex PPARGC1A transcription factor binding network in HepG2 cells. Genome Research 2012, 22: 1668-1679. PMID: 22955979, PMCID: PMC3431484, DOI: 10.1101/gr.127761.111.Peer-Reviewed Original ResearchMeSH KeywordsBinding SitesCarrier ProteinsChromatin ImmunoprecipitationCluster AnalysisGene Expression RegulationGene Regulatory NetworksHeat-Shock ProteinsHep G2 CellsHigh-Throughput Nucleotide SequencingHumansNucleotide MotifsPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaProtein BindingProtein TransportTranscription FactorsTranscription, GeneticConceptsTranscription factorsGenome-wide binding sitesCombinatorial binding patternsHeat shock response pathwayIndividual transcription factorsTranscriptional regulatory networksDNA sequence motifsDifferent transcription factorsShock response pathwayHigh-throughput sequencingMetabolic gene expressionHepG2 cellsTF partnersTranscriptional dynamicsCellular processesChIP-seqSequence motifsRegulatory networksTranscriptional coactivatorResponse pathwaysInterdependent regulationTarget genesChromatin IPRegulatory codeGene expression