In Vitro Genetic Analysis of an Erythrocyte Determinant of Malaria Infection
Bei AK, Brugnara C, Duraisingh MT. In Vitro Genetic Analysis of an Erythrocyte Determinant of Malaria Infection. The Journal Of Infectious Diseases 2010, 202: 1722-1727. PMID: 20958212, PMCID: PMC3107553, DOI: 10.1086/657157.Peer-Reviewed Original ResearchMeSH KeywordsCoculture TechniquesErythrocytesFlow CytometryGlycophorinsHost-Parasite InteractionsHumansMalaria, FalciparumPlasmodium falciparumConceptsGenetic analysisErythrocyte determinantsSystematic functional analysisDirect genetic analysisErythrocyte biologyInvasion of erythrocytesIsogenic backgroundP. falciparum invasionGene expressionFunctional analysisParasite invasionObligatory stepLentiviral transductionHost receptorsGlycophorin ALife cyclePlasmodium falciparumCulture systemInvasionMalaria infectionUnambiguous identificationTransductionBiologyParasitesErythrocytes