Featured Publications
C-Reactive Protein Testing for Active Tuberculosis among Inpatients without HIV in Uganda: a Diagnostic Accuracy Study
Meyer AJ, Ochom E, Turimumahoro P, Byanyima P, Sanyu I, Lalitha R, Kaswabuli S, Andama A, Walter ND, Katamba A, Cattamanchi A, Worodria W, Huang L, Yoon C, Davis JL. C-Reactive Protein Testing for Active Tuberculosis among Inpatients without HIV in Uganda: a Diagnostic Accuracy Study. Journal Of Clinical Microbiology 2020, 59: 10.1128/jcm.02162-20. PMID: 33087439, PMCID: PMC7771459, DOI: 10.1128/jcm.02162-20.Peer-Reviewed Original ResearchConceptsC-reactive proteinEnzyme-linked immunosorbent assayTriage testUtility of CRPC-reactive protein testingCulture-positive pulmonary tuberculosisProspective cross-sectional studySerum C-reactive proteinDiagnostic performanceHIV-seronegative individualsTB triage testNational Referral HospitalCross-sectional studyNegative predictive valueNegative likelihood ratioDiagnostic accuracy studiesActive tuberculosisPulmonary tuberculosisTB screeningReferral hospitalIllness severityCRP testingSputum samplesManufacturer's thresholdPredictive valueSputum quality and diagnostic performance of GeneXpert MTB/RIF among smear-negative adults with presumed tuberculosis in Uganda
Meyer AJ, Atuheire C, Worodria W, Kizito S, Katamba A, Sanyu I, Andama A, Ayakaka I, Cattamanchi A, Bwanga F, Huang L, Davis JL. Sputum quality and diagnostic performance of GeneXpert MTB/RIF among smear-negative adults with presumed tuberculosis in Uganda. PLOS ONE 2017, 12: e0180572. PMID: 28686705, PMCID: PMC5501569, DOI: 10.1371/journal.pone.0180572.Peer-Reviewed Original ResearchConceptsGeneXpert MTB/RIFBlood-stained sputumSputum qualityMTB/RIFSalivary sputumXpert testingDiagnostic performanceMycobacterial cultureCross-sectional studyTB patientsPatient factorsSputum testTB diagnosisDiagnostic yieldMucoid sputumSputum samplesLED fluorescence microscopySputumXpertTuberculosis diagnosticsDemographic informationPatientsAdditional testingHigher proportionSample types
2017
Drop-out from the tuberculosis contact investigation cascade in a routine public health setting in urban Uganda: A prospective, multi-center study
Armstrong-Hough M, Turimumahoro P, Meyer AJ, Ochom E, Babirye D, Ayakaka I, Mark D, Ggita J, Cattamanchi A, Dowdy D, Mugabe F, Fair E, Haberer JE, Katamba A, Davis JL. Drop-out from the tuberculosis contact investigation cascade in a routine public health setting in urban Uganda: A prospective, multi-center study. PLOS ONE 2017, 12: e0187145. PMID: 29108007, PMCID: PMC5673209, DOI: 10.1371/journal.pone.0187145.Peer-Reviewed Original ResearchConceptsHousehold contact investigationNational TB ProgrammeContact investigationTB evaluationActive TBHealth workersPatient householdsMulti-center observational studyIndex TB patientsTB contact investigationLay health workersTuberculosis contact investigationMulti-center studyRoutine public health settingPublic health settingsTB patientsTB programsEligible contactsTuberculosis unitProgrammatic settingsRisk factorsIndex householdsIndex patientsObservational studyRisk contacts