Normal Flow (TIMI-3) Before Mechanical Reperfusion Therapy Is an Independent Determinant of Survival in Acute Myocardial Infarction
Stone G, Cox D, Garcia E, Brodie B, Morice M, Griffin J, Mattos L, Lansky A, O’Neill W, Grines C. Normal Flow (TIMI-3) Before Mechanical Reperfusion Therapy Is an Independent Determinant of Survival in Acute Myocardial Infarction. Circulation 2001, 104: 636-641. PMID: 11489767, DOI: 10.1161/hc3101.093701.Peer-Reviewed Original ResearchConceptsTIMI 3 flowAcute myocardial infarctionInitial TIMI 3 flowMyocardial infarctionPrimary PTCAEarly reperfusionHeart failureIndependent determinantsNew-onset heart failurePostprocedural TIMI 3 flowTIMI 3 flow ratesMechanical reperfusion therapyTIMI 0/1 flowTIMI 2 flowProspective randomized trialsShorter hospital stayVentricular ejection fractionInitial angiographyAngiographic evidenceHospital stayLytic therapyReperfusion therapyVentricular failureSpontaneous reperfusionEarly administration