Almanac 2013: Novel non-coronary cardiac interventions
Meier P, Franzen O, Lansky AJ. Almanac 2013: Novel non-coronary cardiac interventions. Heart 2013, 99: 1309. PMID: 23899781, DOI: 10.1136/heartjnl-2013-304430.Peer-Reviewed Original ResearchMeSH KeywordsAortic Valve StenosisAtrial AppendageAtrial FibrillationCardiologyDenervationEmbolic Protection DevicesEquipment DesignHeart DiseasesHeart Valve DiseasesHeart Valve Prosthesis ImplantationHumansKidneyMitral Valve InsufficiencyPercutaneous Coronary InterventionSeptal Occluder DeviceTreatment OutcomeConceptsHigh riskPercutaneous left atrial appendage closureImportant new treatment optionInterventional cardiologyLeft atrial appendage closureNon-pharmacologic therapiesAtrial appendage closureAortic valve stenosisCoronary artery diseaseAortic valve diseaseSurgical valve repairNew treatment optionsImportant clinical evidenceRecent clinical dataRenal denervationResistant hypertensionStroke preventionAppendage closureElderly patientsArtery diseasePercutaneous treatmentValve stenosisValvular diseaseValve diseaseClinical evidenceStroke prevention by percutaneous closure of patent foramen ovale: a systematic review and meta-analysis
Wolfrum M, Froehlich GM, Knapp G, Casaubon LK, DiNicolantonio JJ, Lansky AJ, Meier P. Stroke prevention by percutaneous closure of patent foramen ovale: a systematic review and meta-analysis. Heart 2013, 100: 389. PMID: 23793373, DOI: 10.1136/heartjnl-2013-304394.Peer-Reviewed Original ResearchConceptsBest medical therapyPatent foramen ovalPercutaneous PFO closurePFO closureCryptogenic strokePercutaneous closureMedical therapyAtrial fibrillationRelative riskSystematic reviewNew-onset atrial fibrillationOnset atrial fibrillationPooled relative riskRisk of bleedingPatent foramen ovaleMain end pointSignificant risk reductionRandom-effects modelStroke preventionMultivariate adjustmentSecondary preventionForamen ovaleClosure groupClinical trialsSignificant treatment effect