2004
Favorable effect of γ‐radiation for in‐stent restenosis: Effect of diabetes on angiographic and clinical outcomes
Iakovou I, Mehran R, Dangas G, Lansky AJ, Stone GW, Mintz GS, Aymong E, Ashby DT, Pichard AD, Satler LF, Kent K, Leon MB, Waksman R. Favorable effect of γ‐radiation for in‐stent restenosis: Effect of diabetes on angiographic and clinical outcomes. Catheterization And Cardiovascular Interventions 2004, 62: 303-307. PMID: 15224295, DOI: 10.1002/ccd.20070.Peer-Reviewed Original ResearchConceptsTarget lesion revascularizationDiabetes mellitusStent restenosisMajor adverse cardiac event ratesAdverse cardiac event ratesIn-Stent Restenosis TrialLower target lesion revascularizationMajor adverse cardiac eventsNon-DM patientsAdverse cardiac eventsCardiac event rateTreatment of ISREffect of diabetesSimilar procedural successGamma radiation therapyLesion revascularizationHospital outcomesRestenosis TrialVessel revascularizationCardiac eventsProcedural successClinical outcomesWashington RadiationVascular brachytherapyPatientsGamma radiation for in‐stent restenosis: effect of lesion length on angiographic and clinical outcomes
Mehran R, Iakovou I, Dangas G, Lansky AJ, Stone GW, Mintz GS, Kent KM, Pichard AD, Satler LF, Fahy M, Leon MB, Waksman R. Gamma radiation for in‐stent restenosis: effect of lesion length on angiographic and clinical outcomes. Catheterization And Cardiovascular Interventions 2004, 61: 354-359. PMID: 14988895, DOI: 10.1002/ccd.10786.Peer-Reviewed Original ResearchConceptsISR groupLesion lengthClinical eventsIn-Stent Restenosis TrialBaseline lesion lengthLower late lossShort lesion groupTreatment of ISRStent restenosis lesionsLong-term outcomesRecurrent ISRRestenosis lesionsRestenosis TrialAngiographic outcomesISR lesionsRestenosis rateClinical outcomesWashington RadiationLate lossStent restenosisLumen dimensionsLong ISRRadiation treatmentPowerful predictorPatients
2002
Quantitative angiographic methods for appropriate end-point analysis, edge-effect evaluation, and prediction of recurrent restenosis after coronary brachytherapy with gamma irradiation
Lansky AJ, Dangas G, Mehran R, Desai KJ, Stone G, Leon M, Mintz G, Waksman R, Wu H, Fahy M. Quantitative angiographic methods for appropriate end-point analysis, edge-effect evaluation, and prediction of recurrent restenosis after coronary brachytherapy with gamma irradiation. Journal Of The American College Of Cardiology 2002, 39: 274-280. PMID: 11788219, DOI: 10.1016/s0735-1097(01)01745-4.Peer-Reviewed Original ResearchConceptsTarget vessel revascularizationRecurrent restenosisDiameter stenosisReceiver operator curveStent restenosisIn-Stent Restenosis TrialIntracoronary radiation therapyPercent diameter stenosisQuantitative coronary angiographyQuantitative angiographic methodsAngiographic locationBlinded therapyRestenosis TrialVessel revascularizationClinical restenosisCoronary angiographyRestenosis rateRestenotic lesionsTreatment failureWashington RadiationBrachytherapy trialsInterventional treatmentVascular brachytherapyEnd-point analysisRadiation therapy
2001
Serial intravascular ultrasound analysis of edge recurrence after intracoronary gamma radiation treatment of native artery in-stent restenosis lesions
Ahmed J, Mintz G, Waksman R, Lansky A, Mehran R, Wu H, Weissman N, Pichard A, Satler L, Kent K, Leon M. Serial intravascular ultrasound analysis of edge recurrence after intracoronary gamma radiation treatment of native artery in-stent restenosis lesions. The American Journal Of Cardiology 2001, 87: 1145-1149. PMID: 11356387, DOI: 10.1016/s0002-9149(01)01483-7.Peer-Reviewed Original ResearchConceptsLumen cross-sectional areaIntimal hyperplasia cross-sectional areaSerial intravascular ultrasound analysisMedia cross-sectional areaEdge recurrenceIntravascular ultrasound analysisCross-sectional areaStent restenosisExternal elastic membrane cross-sectional areaUltrasound analysisStent restenosis TrialStent restenosis lesionsDistal cross-sectional areasGreater decreaseGreater increaseRestenosis lesionsRestenosis TrialPositive remodelingProximal plaqueWashington RadiationNative coronariesMean lumenNeointimal hyperplasiaRecurrenceLesions
2000
Serial volumetric intravascular ultrasound analysis of the efficacy of beta irradiation in preventing recurrent in-stent restenosis
Bhargava B, Mintz G, Mehran R, Lansky A, Weissman N, Walsh C, Chan R, Waksman R. Serial volumetric intravascular ultrasound analysis of the efficacy of beta irradiation in preventing recurrent in-stent restenosis. The American Journal Of Cardiology 2000, 85: 651-653. PMID: 11078283, DOI: 10.1016/s0002-9149(99)00827-9.Peer-Reviewed Original ResearchConceptsRestenosis TrialWashington RadiationVolumetric intravascular ultrasound analysisIntimal hyperplasia volumeSerial Volumetric Intravascular Ultrasound AnalysisIntravascular ultrasound findingsIntravascular ultrasound analysisUltrasound findingsStent restenosisPlaceboUltrasound analysisLumen volumePatientsTrialsBetaGammaBeta irradiationRestenosisPostinterventionRecurrent