2010
Comparison of Catheterization Laboratory Initiated Abciximab and Eptifibatide During Percutaneous Coronary Intervention in Acute Coronary Syndromes (an ACUITY Substudy)
Kirtane AJ, Parise H, Mehran R, Moses JW, Fahy M, Bertrand ME, Ohman EM, White HD, Feit F, Colombo A, McLaurin BT, Cox DA, Ware JH, Pocock SJ, Lansky AJ, Stone GW. Comparison of Catheterization Laboratory Initiated Abciximab and Eptifibatide During Percutaneous Coronary Intervention in Acute Coronary Syndromes (an ACUITY Substudy). The American Journal Of Cardiology 2010, 106: 180-186. PMID: 20599000, DOI: 10.1016/j.amjcard.2010.03.015.Peer-Reviewed Original ResearchConceptsAcute coronary syndromePercutaneous coronary interventionCoronary syndromeCoronary interventionTreatment selectionHigh-risk acute coronary syndromesUrgent Intervention Triage Strategy (ACUITY) trialGlycoprotein IIb/IIIa inhibitorsBaseline cardiac risk factorsNet clinical adverse eventsIIb/IIIa inhibitorsPrevious revascularization proceduresUse of abciximabCardiac risk factorsStudy end pointClinical adverse eventsImproved clinical outcomesST-segment deviationAcute CatheterizationComposite ischemiaMajor bleedingIschemic complicationsAdverse eventsBiomarker elevationRevascularization procedures
2005
Impact of In-Hospital Acquired Thrombocytopenia in Patients Undergoing Primary Angioplasty for Acute Myocardial Infarction
Nikolsky E, Sadeghi HM, Effron MB, Mehran R, Lansky AJ, Na Y, Cox DA, Garcia E, Tcheng JE, Griffin JJ, Stuckey TD, Turco M, Carroll JD, Grines CL, Stone GW. Impact of In-Hospital Acquired Thrombocytopenia in Patients Undergoing Primary Angioplasty for Acute Myocardial Infarction. The American Journal Of Cardiology 2005, 96: 474-481. PMID: 16098296, DOI: 10.1016/j.amjcard.2005.04.005.Peer-Reviewed Original ResearchMeSH KeywordsAbciximabAge DistributionAgedAngioplasty, Balloon, CoronaryAntibodies, MonoclonalCause of DeathFemaleFollow-Up StudiesHemorrhageHumansImmunoglobulin Fab FragmentsIncidenceInpatientsMaleMiddle AgedMyocardial InfarctionOdds RatioPlatelet Aggregation InhibitorsPlatelet CountProspective StudiesRisk FactorsSex DistributionSurvival RateThrombocytopeniaTreatment OutcomeConceptsPrimary percutaneous coronary interventionPercutaneous coronary interventionAcute myocardial infarctionHemorrhagic complicationsAcquired thrombocytopeniaPlatelet countMyocardial infarctionHigher baseline platelet countGreater body mass indexNadir platelet countPrevious aspirin useUse of abciximabBaseline platelet countBlood product transfusionLonger hospital stayMajor hemorrhagic complicationsHours of onsetBody mass indexAspirin useBaseline thrombocytopeniaCADILLAC trialIschemic complicationsCause mortalityHospital stayPrimary angioplasty