2012
Impact of the Presence and Extent of Incomplete Angiographic Revascularization After Percutaneous Coronary Intervention in Acute Coronary Syndromes
Rosner GF, Kirtane AJ, Genereux P, Lansky AJ, Cristea E, Gersh BJ, Weisz G, Parise H, Fahy M, Mehran R, Stone GW. Impact of the Presence and Extent of Incomplete Angiographic Revascularization After Percutaneous Coronary Intervention in Acute Coronary Syndromes. Circulation 2012, 125: 2613-2620. PMID: 22550156, DOI: 10.1161/circulationaha.111.069237.Peer-Reviewed Original ResearchConceptsMajor adverse cardiac eventsIncomplete coronary revascularizationPercutaneous coronary interventionAdverse cardiac eventsAcute coronary syndromeCoronary interventionCoronary syndromeCardiac eventsUnplanned revascularizationMyocardial infarctionMajor adverse cardiac event ratesUrgent Intervention Triage Strategy (ACUITY) trialAdverse cardiac event ratesCardiac event rateReference vessel diameterEntire coronary treeAcute CatheterizationAngiographic revascularizationCoronary revascularizationIndependent predictorsPrimary outcomeMultivariable analysisStrategy trialQuantitative angiographyClinical significance
2010
Surgical Versus Percutaneous Revascularization for Multivessel Disease in Patients With Acute Coronary Syndromes Analysis From the ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy) Trial
Ben-Gal Y, Moses JW, Mehran R, Lansky AJ, Weisz G, Nikolsky E, Argenziano M, Williams MR, Colombo A, Aylward PE, Stone GW. Surgical Versus Percutaneous Revascularization for Multivessel Disease in Patients With Acute Coronary Syndromes Analysis From the ACUITY (Acute Catheterization and Urgent Intervention Triage Strategy) Trial. JACC Cardiovascular Interventions 2010, 3: 1059-1067. PMID: 20965465, DOI: 10.1016/j.jcin.2010.06.017.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeAcute Kidney InjuryAgedAngioplasty, Balloon, CoronaryBlood TransfusionCoronary AngiographyCoronary Artery BypassFemaleHumansKaplan-Meier EstimateLogistic ModelsMaleMiddle AgedMyocardial InfarctionPlatelet Aggregation InhibitorsPropensity ScoreRecurrenceRisk AssessmentRisk FactorsStrokeTime FactorsTreatment OutcomeConceptsPercutaneous coronary interventionAcute coronary syndromeHigh-risk patientsMultivessel diseaseACUITY trialRenal injuryMyocardial infarctionHigh-risk acute coronary syndromesAcute Coronary Syndromes AnalysisHigh-risk ACS patientsMultivessel coronary artery diseasePeri-procedural strokePreferred revascularization strategyPropensity-matched comparisonPropensity-matched patientsAcute renal injuryCoronary artery bypassOutcomes of patientsMore blood transfusionsCoronary artery diseaseRepeat revascularization proceduresACS patientsMajor bleedingPCI groupUnplanned revascularization
2004
Acute Catheterization and Urgent Intervention Triage strategY (ACUITY) trial: Study design and rationale
Stone GW, Bertrand M, Colombo A, Dangas G, Farkouh ME, Feit F, Lansky AJ, Lincoff AM, Mehran R, Moses JW, Ohman M, White HD. Acute Catheterization and Urgent Intervention Triage strategY (ACUITY) trial: Study design and rationale. American Heart Journal 2004, 148: 764-775. PMID: 15523305, DOI: 10.1016/j.ahj.2004.04.036.Peer-Reviewed Original ResearchMeSH KeywordsAngina, UnstableAngioplasty, Balloon, CoronaryAnticoagulantsAntithrombinsCardiac CatheterizationCombined Modality TherapyCoronary Artery BypassEnoxaparinHeparinHirudinsHumansMulticenter Studies as TopicMyocardial InfarctionPeptide FragmentsPlatelet Glycoprotein GPIIb-IIIa ComplexProspective StudiesRandomized Controlled Trials as TopicRecombinant ProteinsResearch DesignConceptsIIb/IIIa inhibitionUrgent Intervention Triage Strategy (ACUITY) trialIIb/IIIa inhibitorsAcute CatheterizationInhibitor administrationStrategy trialMyocardial infarctionGlycoprotein IIb/IIIa inhibitorsPrimary study end pointAdverse ischemic eventsHigh-risk ACSComposite of deathStudy end pointAcute coronary syndromeHigh-risk patientsSurgical revascularization proceduresTreatment of choiceSecond random assignmentACUITY trialMajor bleedingSurgical revascularizationUnplanned revascularizationCoronary syndromeEarly angiographyIschemic events