2007
Impact of Time to Treatment on Myocardial Reperfusion and Infarct Size With Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction (from the EMERALD Trial)
Brodie BR, Webb J, Cox DA, Qureshi M, Kalynych A, Turco M, Schultheiss HP, Dulas D, Rutherford B, Antoniucci D, Stuckey T, Krucoff M, Gibbons R, Lansky A, Na Y, Mehran R, Stone GW, Investigators E. Impact of Time to Treatment on Myocardial Reperfusion and Infarct Size With Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction (from the EMERALD Trial). The American Journal Of Cardiology 2007, 99: 1680-1686. PMID: 17560875, DOI: 10.1016/j.amjcard.2007.01.047.Peer-Reviewed Original ResearchConceptsPrimary percutaneous coronary interventionPrimary PCIPercutaneous coronary interventionSmaller infarct sizeInfarct sizeNonanterior infarctionDistal protectionCoronary interventionMyocardial infarctionST-elevation myocardial infarctionHigh-risk patientsTriage of patientsAcute myocardial infarctionEMERALD trialImpact of timeControl patientsEarly reperfusionMyocardial reperfusionClinical outcomesAnterior infarctionMyocardial blushReperfusionInfarctionMortality ratePatients
2001
Importance of time to reperfusion on outcomes with primary coronary angioplasty for acute myocardial infarction (results from the Stent Primary Angioplasty in Myocardial Infarction Trial)
Brodie B, Stone G, Morice M, Cox D, Garcia E, Mattos L, Boura J, O’Neill W, Stuckey T, Milks S, Lansky A, Grines C, Group F. Importance of time to reperfusion on outcomes with primary coronary angioplasty for acute myocardial infarction (results from the Stent Primary Angioplasty in Myocardial Infarction Trial). The American Journal Of Cardiology 2001, 88: 1085-1090. PMID: 11703949, DOI: 10.1016/s0002-9149(01)02039-2.Peer-Reviewed Original ResearchConceptsPrimary percutaneous transluminal coronary angioplastyPrimary PTCAAcute myocardial infarctionCardiogenic shockCoronary angioplastyMyocardial infarctionMyocardial Infarction (TIMI) grade 3 flowPercutaneous transluminal coronary angioplastyInfarct artery reocclusionStent-PAMI trialGrade 3 flowPrimary coronary angioplastyTransluminal coronary angioplastyTriage of patientsArtery reocclusionMortality benefitSurvival benefitEjection fractionLate reperfusionClinical outcomesMyocardial salvageThrombolytic therapyReperfusionPatientsLack of correlation