2017
Nine‐month results of the BIOHELIX‐I clinical trial study: Evaluation of the PRO‐Kinetic Energy cobalt chromium bare‐metal stent system
Michael TT, Richardt G, Lansky A, Carney RJ, Khan MA, Shehadeh A, Zeymer U, Gupta S. Nine‐month results of the BIOHELIX‐I clinical trial study: Evaluation of the PRO‐Kinetic Energy cobalt chromium bare‐metal stent system. Catheterization And Cardiovascular Interventions 2017, 92: 1030-1039. PMID: 29271575, DOI: 10.1002/ccd.27434.Peer-Reviewed Original ResearchConceptsTarget vessel revascularizationCoronary artery diseaseIschemia-driven target vessel revascularizationBare metal stentsTarget vessel failureTVF ratePrimary endpointStent systemSymptomatic coronary artery diseaseTarget lesion revascularization rateSingle-arm clinical trialNine‐month resultsDual antiplatelet therapyLesion revascularization rateMean patient agePercutaneous coronary interventionSubset of patientsClinical trial studyPrespecified performance goalArm clinical trialCoronary stent systemDrug-eluting stentsMean lesion lengthMajority of implantsEligible patients
2009
Impact of Myocardial Bridge on Clinical Outcome After Coronary Stent Placement
Tsujita K, Maehara A, Mintz GS, Doi H, Kubo T, Castellanos C, Liu J, Yang J, Oviedo C, Franklin-Bond T, Sugirtharaj DD, Dangas GD, Lansky AJ, Stone GW, Moses JW, Leon MB, Mehran R. Impact of Myocardial Bridge on Clinical Outcome After Coronary Stent Placement. The American Journal Of Cardiology 2009, 103: 1344-1348. PMID: 19427426, DOI: 10.1016/j.amjcard.2009.01.340.Peer-Reviewed Original ResearchConceptsTarget lesion revascularizationCoronary stent placementStent placementMyocardial bridgeArtery lesionsObstructive lesionsClinical outcomesStent groupTarget lesion revascularization rateStent group patientsTarget vessel revascularizationComposite end pointCoronary artery lesionsMinimum stent areaGroup patientsRevascularization ratesConsecutive patientsLeft anteriorObstructive diseaseSystolic compressionCoronary arterySignificant plaqueStent areaStent restenosisIntravascular ultrasound
2004
Short- and long-term results after multivessel stenting in diabetic patients
Moses J, Mehran R, Dangas G, Kobayashi Y, Lansky A, Mintz G, Aymong E, Fahy M, Stone GW, Leon MB. Short- and long-term results after multivessel stenting in diabetic patients. Journal Of The American College Of Cardiology 2004, 43: 1348-1354. PMID: 15093865, DOI: 10.1016/j.jacc.2003.04.004.Peer-Reviewed Original ResearchConceptsCoronary artery bypass graft surgeryNon-diabetic patientsHospital coronary artery bypass graft surgeryOne-year survivalDiabetic patientsMultivessel stentingOral agentsRevascularization ratesClinical outcomesProcedural successMyocardial infarctionTarget lesion revascularization rateArtery bypass graft surgeryHigh technical success rateDiabetes mellitus statusExcellent procedural successHospital cardiac deathSubsequent revascularization ratesBypass graft surgeryLesion revascularization rateNative coronary lesionsOne-year mortalityTechnical success rateConventional balloon angioplastyAcceptable clinical outcomes
2002
Clinical and angiographic outcomes after use of 90Strontium/90Yttrium beta radiation for the treatment of in-stent restenosis: results from the Stents and Radiation Therapy 40 (START 40) registry
Suntharalingam M, Laskey W, Lansky AJ, Waksman R, White L, Teirstien P, Massullo V, Rutherford B, Elman A, Kuntz RE, Popma JJ, Bonan R, Investigators T. Clinical and angiographic outcomes after use of 90Strontium/90Yttrium beta radiation for the treatment of in-stent restenosis: results from the Stents and Radiation Therapy 40 (START 40) registry. International Journal Of Radiation Oncology • Biology • Physics 2002, 52: 1075-1082. PMID: 11958904, DOI: 10.1016/s0360-3016(01)02712-2.Peer-Reviewed Original ResearchConceptsMinimum luminal diameterPlacebo groupStent restenosisAngiographic analysisInjury lengthBinary restenosisRevascularization ratesPlacebo armSTART trialSource trainTarget vessel revascularization rateMajor adverse cardiac eventsTarget lesion revascularization rateAdverse cardiac eventsLesion revascularization rateRepeat balloon angioplastyVessel revascularization rateTarget vessel revascularizationNative coronary arteriesManagement of patientsRate of restenosisQuantitative angiographic analysisResults of patientsLate aneurysm formationPercent diameter stenosis
2000
Treatment of In-Stent Restenosis With Excimer Laser Coronary Angioplasty Versus Rotational Atherectomy
Mehran R, Dangas G, Mintz G, Waksman R, Abizaid A, Satler L, Pichard A, Kent K, Lansky A, Stone G, Leon M. Treatment of In-Stent Restenosis With Excimer Laser Coronary Angioplasty Versus Rotational Atherectomy. Circulation 2000, 101: 2484-2489. PMID: 10831522, DOI: 10.1161/01.cir.101.21.2484.Peer-Reviewed Original ResearchConceptsExcimer laser coronary angioplastyVolumetric IVUS analysisRotational atherectomyQuantitative coronary angiographicClinical resultsCoronary angiographicIVUS analysisLumen enlargementSimilar long-term clinical outcomesTarget lesion revascularization rateLong-term clinical outcomesSignificant between-group differencesIntimal hyperplasia volumeLesion revascularization rateLaser coronary angioplastyTreatment of diffuseIn-Stent RestenosisSimilar clinical resultsBetween-group differencesIntravascular ultrasound measurementsAdjunct PTCADiffuse ISRHospital complicationsAngiographic successRevascularization ratesIntracoronary β-Radiation Therapy Inhibits Recurrence of In-Stent Restenosis
Waksman R, Bhargava B, White L, Chan R, Mehran R, Lansky A, Mintz G, Satler L, Pichard A, Leon M, Kent K. Intracoronary β-Radiation Therapy Inhibits Recurrence of In-Stent Restenosis. Circulation 2000, 101: 1895-1898. PMID: 10779453, DOI: 10.1161/01.cir.101.16.1895.Peer-Reviewed Original ResearchConceptsRevascularization ratesBinary angiographic restenosis rateIntracoronary gamma radiation therapyTarget vessel revascularization rateTarget lesion revascularization ratePercutaneous transluminal coronary angioplastyVessel revascularization rateAngiographic restenosis rateLesion revascularization rateTransluminal coronary angioplastyIn-Stent RestenosisGamma radiation therapyRecurrent ISRPlacebo groupClinical restenosisAdjunct therapyConsecutive patientsCoronary angioplastyRestenosis rateRotational atherectomyStent implantationBalloon catheterNative coronariesStent restenosisPatientsEffect of plaque debulking and stenting on short- and long-term outcomes after revascularization of chronic total occlusions
Gruberg L, Mehran R, Dangas G, Hong M, Mintz G, Kornowski R, Lansky A, Kent K, Pichard A, Satler L, Stone G, Leon M. Effect of plaque debulking and stenting on short- and long-term outcomes after revascularization of chronic total occlusions. Journal Of The American College Of Cardiology 2000, 35: 151-156. PMID: 10636273, DOI: 10.1016/s0735-1097(99)00491-x.Peer-Reviewed Original ResearchConceptsLesion revascularization rateChronic total occlusionRevascularization ratesClinical outcomesTotal occlusionCoronary arteryStent deploymentTarget lesion revascularization rateLong-term clinical outcomesCoronary artery locationLate clinical outcomesPrimary success rateNative coronary arteriesGroup of patientsCoronary artery occlusionLong-term outcomesSuccessful stent deploymentNew interventional devicesEffect of plaqueAngioplasty ratesHospital mortalityLesion modificationSuccessful stentingAngiographic characteristicsHospital outcomes
1999
Preintervention Arterial Remodeling as an Independent Predictor of Target-Lesion Revascularization After Nonstent Coronary Intervention
Dangas G, Mintz G, Mehran R, Lansky A, Kornowski R, Pichard A, Satler L, Kent K, Stone G, Leon M. Preintervention Arterial Remodeling as an Independent Predictor of Target-Lesion Revascularization After Nonstent Coronary Intervention. Circulation 1999, 99: 3149-3154. PMID: 10377078, DOI: 10.1161/01.cir.99.24.3149.Peer-Reviewed Original ResearchConceptsIndependent predictorsArterial remodelingTarget lesion revascularization rateInsulin-dependent diabetic patientsLong-term clinical outcomesQ-wave myocardial infarctionMultivariable logistic regression analysisTarget lesion revascularizationShort-term complicationsIntravascular ultrasound studyLong-term outcomesFinal lumen areaLogistic regression analysisIntermediate remodelingAngiographic characteristicsAngiographic successRevascularization ratesCoronary interventionClinical outcomesDiabetic patientsPlaque burdenPositive remodelingMyocardial infarctionNegative remodelingPercutaneous intervention