2024
Cerebrovascular Events in Patients Undergoing Transcatheter Aortic Valve Replacement: A Review
Patel K, Rathod K, Lansky A, Prendergast B, Kharbanda R, Mathur A, Perry R, Baumbach A. Cerebrovascular Events in Patients Undergoing Transcatheter Aortic Valve Replacement: A Review. Stroke 2024, 55: 2754-2764. PMID: 39371005, DOI: 10.1161/strokeaha.124.047149.Peer-Reviewed Original ResearchTranscatheter aortic valve replacementAortic valve replacementCerebrovascular eventsValve replacementAtrial fibrillationLow operative risk patientsAdvent of transcatheter aortic valve replacementNew-onset atrial fibrillationComplication of transcatheter aortic valve replacementIncreased risk of bleedingHigher risk of cerebrovascular eventsAssociated with significant mortalityTranscatheter aortic valve replacement procedureRisk of cerebrovascular eventsOperative risk patientsResults of embolizationRisk of bleedingRisk of thromboembolismHypoattenuated leaflet thickeningImprove risk stratificationCerebral lesion volumeAssociated with cerebrovascular eventsTherapy to patientsOverall stroke rateSeverity of comorbidities
2013
Stroke prevention by percutaneous closure of patent foramen ovale: a systematic review and meta-analysis
Wolfrum M, Froehlich GM, Knapp G, Casaubon LK, DiNicolantonio JJ, Lansky AJ, Meier P. Stroke prevention by percutaneous closure of patent foramen ovale: a systematic review and meta-analysis. Heart 2013, 100: 389. PMID: 23793373, DOI: 10.1136/heartjnl-2013-304394.Peer-Reviewed Original ResearchConceptsBest medical therapyPatent foramen ovalPercutaneous PFO closurePFO closureCryptogenic strokePercutaneous closureMedical therapyAtrial fibrillationRelative riskSystematic reviewNew-onset atrial fibrillationOnset atrial fibrillationPooled relative riskRisk of bleedingPatent foramen ovaleMain end pointSignificant risk reductionRandom-effects modelStroke preventionMultivariate adjustmentSecondary preventionForamen ovaleClosure groupClinical trialsSignificant treatment effect