Effect of Supersaturated Oxygen Delivery on Infarct Size After Percutaneous Coronary Intervention in Acute Myocardial Infarction
Stone GW, Martin JL, de Boer MJ, Margheri M, Bramucci E, Blankenship JC, Metzger DC, Gibbons RJ, Lindsay BS, Weiner BH, Lansky AJ, Krucoff MW, Fahy M, Boscardin WJ. Effect of Supersaturated Oxygen Delivery on Infarct Size After Percutaneous Coronary Intervention in Acute Myocardial Infarction. Circulation Cardiovascular Interventions 2009, 2: 366-375. PMID: 20031745, DOI: 10.1161/circinterventions.108.840066.Peer-Reviewed Original ResearchConceptsST-segment elevation myocardial infarctionMajor adverse cardiovascular eventsElevation myocardial infarctionPercutaneous coronary interventionAdverse cardiovascular eventsAnterior ST-segment elevation myocardial infarctionInfarct sizeCoronary interventionMyocardial infarctionCardiovascular eventsLeft anteriorSymptom onsetLarge ST-segment elevation myocardial infarctionComposite major adverse cardiovascular eventsSestamibi single-photon emissionMedian infarct sizePosthoc subgroup analysisPrimary efficacy measureAcute myocardial infarctionPrimary safety measureSingle photon emissionNoninferior ratesTreat populationProtocol populationMulticenter trial