2014
Local versus general anesthesia for transcatheter aortic valve implantation (TAVR) – systematic review and meta-analysis
Fröhlich GM, Lansky AJ, Webb J, Roffi M, Toggweiler S, Reinthaler M, Wang D, Hutchinson N, Wendler O, Hildick-Smith D, Meier P. Local versus general anesthesia for transcatheter aortic valve implantation (TAVR) – systematic review and meta-analysis. BMC Medicine 2014, 12: 41. PMID: 24612945, PMCID: PMC4022332, DOI: 10.1186/1741-7015-12-41.Peer-Reviewed Original ResearchConceptsShorter hospital stayGeneral anesthesiaHospital stayRelative riskProcedure timeSevere aortic valve stenosisTranscatheter aortic valve implantationResultsSeven observational studiesAcute kidney injuryProcedure-related mortalityPooled relative riskAortic valve implantationAortic valve stenosisShort-term outcomesShorter procedure timeRandom-effects modelKidney injuryValve implantationOverall mortalityValve stenosisRandomized trialsTransfemoral TAVRLocal anesthesiaTreatment optionsMyocardial infarction
2009
Safety and Efficacy of Drug-Eluting and Bare Metal Stents
Kirtane AJ, Gupta A, Iyengar S, Moses JW, Leon MB, Applegate R, Brodie B, Hannan E, Harjai K, Jensen LO, Park SJ, Perry R, Racz M, Saia F, Tu JV, Waksman R, Lansky AJ, Mehran R, Stone GW. Safety and Efficacy of Drug-Eluting and Bare Metal Stents. Circulation 2009, 119: 3198-3206. PMID: 19528338, DOI: 10.1161/circulationaha.108.826479.Peer-Reviewed Original ResearchConceptsBare metal stentsDrug-eluting stentsTarget vessel revascularizationMyocardial infarctionVessel revascularizationObservational studyMetal stentsEfficacy end pointTotal patientsOverall mortalityDrug-ElutingDES useLabel indicationsLabel useResidual confoundingBMS useRCTsPatientsDrug AdministrationInfarctionRevascularizationEnd pointMortality dataComparable reductionStents