A composite peripheral blood gene expression score has high sensitivity for obstructive coronary artery disease in a non-invasive imaging population and correlates with plaque burden and morphology by
Voros S, Thomas G, Bateman T, Mcpherson J, Lansky A, Douglas P, Ladapo J, Wingrove J, Elashoff M, Rosenberg S. A composite peripheral blood gene expression score has high sensitivity for obstructive coronary artery disease in a non-invasive imaging population and correlates with plaque burden and morphology by. European Heart Journal 2013, 34: p2413. DOI: 10.1093/eurheartj/eht308.p2413.Peer-Reviewed Original ResearchMyocardial perfusion imagingNon-calcified plaquePlaque burdenInvasive angiogramObstructive coronary artery diseaseQuantitative CTA analysisNon-diabetic patientsCoronary artery diseaseOverall plaque burdenQuantitative coronary angiographyNegative predictive valueGene expression scoreNeutrophil upregulationArtery diseaseCalcium scoreCoronary angiographyInvasive angiographyGES scoresCAD casesBlood samplesCTA analysisPatientsPerfusion imagingReferral pathsPredictive value