Magnitude and impact of treatment delays on weeknights and weekends in patients undergoing primary angioplasty for acute myocardial infarction (the cadillac trial)
Sadeghi HM, Grines CL, Chandra HR, Mehran R, Fahy M, Cox DA, Garcia E, Tcheng JE, Griffin JJ, Stuckey TD, Lansky AJ, O'Neill WW, Stone GW. Magnitude and impact of treatment delays on weeknights and weekends in patients undergoing primary angioplasty for acute myocardial infarction (the cadillac trial). The American Journal Of Cardiology 2004, 94: 637-640. PMID: 15342297, DOI: 10.1016/j.amjcard.2004.05.030.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionAcute myocardial infarctionMyocardial infarctionOutcomes of patientsCADILLAC trialPrimary angioplastyCoronary interventionProcedural successTreatment delayMyocardial recoveryPatientsModest delayInfarctionWeeknightsHoursTreatment timeAngioplastyWeekendsTrialsImpact of intravenous Beta-Blockade before primary angioplasty on survival in patients undergoing mechanical reperfusion therapy for acute myocardial infarction
Halkin A, Grines CL, Cox DA, Garcia E, Mehran R, Tcheng JE, Griffin JJ, Guagliumi G, Brodie B, Turco M, Rutherford BD, Aymong E, Lansky AJ, Stone GW. Impact of intravenous Beta-Blockade before primary angioplasty on survival in patients undergoing mechanical reperfusion therapy for acute myocardial infarction. Journal Of The American College Of Cardiology 2004, 43: 1780-1787. PMID: 15145099, DOI: 10.1016/j.jacc.2003.10.068.Peer-Reviewed Original ResearchConceptsPrimary percutaneous coronary interventionAcute myocardial infarctionPrimary PCIBeta-blocker useMyocardial recoveryMyocardial infarctionLate Angioplasty Complications (CADILLAC) trialOral beta-blocker medicationOral beta-blocker useLeft ventricular ejection fractionIntravenous beta blockadeMechanical reperfusion therapyAbsence of contraindicationsBeta-blocker therapyBeta-blocker medicationBeta-blocker administrationPercutaneous coronary interventionVentricular ejection fractionBeta blockadeControlled AbciximabPrimary angioplastyReperfusion therapyComplications TrialCoronary interventionSurvival benefit