2017
Nine‐month results of the BIOHELIX‐I clinical trial study: Evaluation of the PRO‐Kinetic Energy cobalt chromium bare‐metal stent system
Michael TT, Richardt G, Lansky A, Carney RJ, Khan MA, Shehadeh A, Zeymer U, Gupta S. Nine‐month results of the BIOHELIX‐I clinical trial study: Evaluation of the PRO‐Kinetic Energy cobalt chromium bare‐metal stent system. Catheterization And Cardiovascular Interventions 2017, 92: 1030-1039. PMID: 29271575, DOI: 10.1002/ccd.27434.Peer-Reviewed Original ResearchConceptsTarget vessel revascularizationCoronary artery diseaseIschemia-driven target vessel revascularizationBare metal stentsTarget vessel failureTVF ratePrimary endpointStent systemSymptomatic coronary artery diseaseTarget lesion revascularization rateSingle-arm clinical trialNine‐month resultsDual antiplatelet therapyLesion revascularization rateMean patient agePercutaneous coronary interventionSubset of patientsClinical trial studyPrespecified performance goalArm clinical trialCoronary stent systemDrug-eluting stentsMean lesion lengthMajority of implantsEligible patientsImpact of Stent Size Selection on Acute and Long-Term Outcomes After Drug-Eluting Stent Implantation in De Novo Coronary Lesions
Kitahara H, Okada K, Kimura T, Yock PG, Lansky AJ, Popma JJ, Yeung AC, Fitzgerald PJ, Honda Y. Impact of Stent Size Selection on Acute and Long-Term Outcomes After Drug-Eluting Stent Implantation in De Novo Coronary Lesions. Circulation Cardiovascular Interventions 2017, 10: e004795. PMID: 28951394, DOI: 10.1161/circinterventions.116.004795.Peer-Reviewed Original ResearchConceptsDrug-eluting stent implantationReference vessel diameterLong-term outcomesDe novo coronary lesionsNovo coronary lesionsStent implantationDrug-eluting stentsIncomplete stent appositionClinical outcomesCoronary lesionsStent thrombosisStent oversizingStent appositionAngiographic reference vessel diameterSmaller reference vessel diameterGreater stent expansionLesion revascularization rateTarget lesion revascularizationGreater adverse eventsSerial coronary angiographyArterial wall injuryStent size selectionLesion revascularizationRevascularization ratesAdverse events
2004
Short- and long-term results after multivessel stenting in diabetic patients
Moses J, Mehran R, Dangas G, Kobayashi Y, Lansky A, Mintz G, Aymong E, Fahy M, Stone GW, Leon MB. Short- and long-term results after multivessel stenting in diabetic patients. Journal Of The American College Of Cardiology 2004, 43: 1348-1354. PMID: 15093865, DOI: 10.1016/j.jacc.2003.04.004.Peer-Reviewed Original ResearchConceptsCoronary artery bypass graft surgeryNon-diabetic patientsHospital coronary artery bypass graft surgeryOne-year survivalDiabetic patientsMultivessel stentingOral agentsRevascularization ratesClinical outcomesProcedural successMyocardial infarctionTarget lesion revascularization rateArtery bypass graft surgeryHigh technical success rateDiabetes mellitus statusExcellent procedural successHospital cardiac deathSubsequent revascularization ratesBypass graft surgeryLesion revascularization rateNative coronary lesionsOne-year mortalityTechnical success rateConventional balloon angioplastyAcceptable clinical outcomes
2002
Clinical and angiographic outcomes after use of 90Strontium/90Yttrium beta radiation for the treatment of in-stent restenosis: results from the Stents and Radiation Therapy 40 (START 40) registry
Suntharalingam M, Laskey W, Lansky AJ, Waksman R, White L, Teirstien P, Massullo V, Rutherford B, Elman A, Kuntz RE, Popma JJ, Bonan R, Investigators T. Clinical and angiographic outcomes after use of 90Strontium/90Yttrium beta radiation for the treatment of in-stent restenosis: results from the Stents and Radiation Therapy 40 (START 40) registry. International Journal Of Radiation Oncology • Biology • Physics 2002, 52: 1075-1082. PMID: 11958904, DOI: 10.1016/s0360-3016(01)02712-2.Peer-Reviewed Original ResearchConceptsMinimum luminal diameterPlacebo groupStent restenosisAngiographic analysisInjury lengthBinary restenosisRevascularization ratesPlacebo armSTART trialSource trainTarget vessel revascularization rateMajor adverse cardiac eventsTarget lesion revascularization rateAdverse cardiac eventsLesion revascularization rateRepeat balloon angioplastyVessel revascularization rateTarget vessel revascularizationNative coronary arteriesManagement of patientsRate of restenosisQuantitative angiographic analysisResults of patientsLate aneurysm formationPercent diameter stenosis
2001
Treatment of focal in-stent restenosis with balloon angioplasty alone versus stenting: Short- and long-term results
Mehran R, Dangas G, Abizaid A, Lansky A, Mintz G, Pichard A, Satler L, Kent K, Waksman R, Stone G, Leon M. Treatment of focal in-stent restenosis with balloon angioplasty alone versus stenting: Short- and long-term results. American Heart Journal 2001, 141: 610-614. PMID: 11275928, DOI: 10.1067/mhj.2001.113998.Peer-Reviewed Original ResearchConceptsPercutaneous transluminal coronary angioplastyMinimal lumen diameterLong-term clinical resultsFocal ISRStent groupClinical resultsStent restenosisLarger reference vessel diameterLesion lengthLesion revascularization rateTarget lesion revascularizationReference vessel diameterResidual diameter stenosisTransluminal coronary angioplastyLong-term resultsQ-wave infarctionPTCA groupUrgent revascularizationAngiographic successLesion revascularizationRevascularization ratesAdditional stentingBaseline characteristicsCoronary angioplastyDiabetic patients
2000
Treatment of In-Stent Restenosis With Excimer Laser Coronary Angioplasty Versus Rotational Atherectomy
Mehran R, Dangas G, Mintz G, Waksman R, Abizaid A, Satler L, Pichard A, Kent K, Lansky A, Stone G, Leon M. Treatment of In-Stent Restenosis With Excimer Laser Coronary Angioplasty Versus Rotational Atherectomy. Circulation 2000, 101: 2484-2489. PMID: 10831522, DOI: 10.1161/01.cir.101.21.2484.Peer-Reviewed Original ResearchConceptsExcimer laser coronary angioplastyVolumetric IVUS analysisRotational atherectomyQuantitative coronary angiographicClinical resultsCoronary angiographicIVUS analysisLumen enlargementSimilar long-term clinical outcomesTarget lesion revascularization rateLong-term clinical outcomesSignificant between-group differencesIntimal hyperplasia volumeLesion revascularization rateLaser coronary angioplastyTreatment of diffuseIn-Stent RestenosisSimilar clinical resultsBetween-group differencesIntravascular ultrasound measurementsAdjunct PTCADiffuse ISRHospital complicationsAngiographic successRevascularization ratesIntracoronary β-Radiation Therapy Inhibits Recurrence of In-Stent Restenosis
Waksman R, Bhargava B, White L, Chan R, Mehran R, Lansky A, Mintz G, Satler L, Pichard A, Leon M, Kent K. Intracoronary β-Radiation Therapy Inhibits Recurrence of In-Stent Restenosis. Circulation 2000, 101: 1895-1898. PMID: 10779453, DOI: 10.1161/01.cir.101.16.1895.Peer-Reviewed Original ResearchConceptsRevascularization ratesBinary angiographic restenosis rateIntracoronary gamma radiation therapyTarget vessel revascularization rateTarget lesion revascularization ratePercutaneous transluminal coronary angioplastyVessel revascularization rateAngiographic restenosis rateLesion revascularization rateTransluminal coronary angioplastyIn-Stent RestenosisGamma radiation therapyRecurrent ISRPlacebo groupClinical restenosisAdjunct therapyConsecutive patientsCoronary angioplastyRestenosis rateRotational atherectomyStent implantationBalloon catheterNative coronariesStent restenosisPatientsEffect of plaque debulking and stenting on short- and long-term outcomes after revascularization of chronic total occlusions
Gruberg L, Mehran R, Dangas G, Hong M, Mintz G, Kornowski R, Lansky A, Kent K, Pichard A, Satler L, Stone G, Leon M. Effect of plaque debulking and stenting on short- and long-term outcomes after revascularization of chronic total occlusions. Journal Of The American College Of Cardiology 2000, 35: 151-156. PMID: 10636273, DOI: 10.1016/s0735-1097(99)00491-x.Peer-Reviewed Original ResearchConceptsLesion revascularization rateChronic total occlusionRevascularization ratesClinical outcomesTotal occlusionCoronary arteryStent deploymentTarget lesion revascularization rateLong-term clinical outcomesCoronary artery locationLate clinical outcomesPrimary success rateNative coronary arteriesGroup of patientsCoronary artery occlusionLong-term outcomesSuccessful stent deploymentNew interventional devicesEffect of plaqueAngioplasty ratesHospital mortalityLesion modificationSuccessful stentingAngiographic characteristicsHospital outcomes