A Prospective Natural-History Study of Coronary Atherosclerosis
Stone GW, Maehara A, Lansky AJ, de Bruyne B, Cristea E, Mintz GS, Mehran R, McPherson J, Farhat N, Marso SP, Parise H, Templin B, White R, Zhang Z, Serruys PW. A Prospective Natural-History Study of Coronary Atherosclerosis. New England Journal Of Medicine 2011, 364: 226-235. PMID: 21247313, DOI: 10.1056/nejmoa1002358.Peer-Reviewed Original ResearchMeSH KeywordsAcute Coronary SyndromeAgedAngioplasty, Balloon, CoronaryCoronary AngiographyCoronary Artery DiseaseCoronary VesselsDisease ProgressionFemaleHumansKaplan-Meier EstimateMaleMiddle AgedPatient ReadmissionProportional Hazards ModelsProspective StudiesRecurrenceRisk FactorsUltrasonography, InterventionalConceptsMajor adverse cardiovascular eventsAdverse cardiovascular eventsAcute coronary syndromeNonculprit lesionsPercutaneous coronary interventionThin-cap fibroatheromaCardiovascular eventsCoronary syndromeCulprit lesionCoronary interventionPlaque burdenIntravascular ultrasonographyLuminal areaSubsequent major adverse cardiovascular eventsLesion-related risk factorsMild coronary artery stenosisProspective natural history studyLarger plaque burdenCoronary artery stenosisMinimal luminal areaNatural history studiesRecurrent eventsSmall luminal areaMedian followCoronary atherosclerosis