2008
Angiographic Patterns of Drug-Eluting Stent Restenosis and One-Year Outcomes After Treatment With Repeated Percutaneous Coronary Intervention
Solinas E, Dangas G, Kirtane AJ, Lansky AJ, Franklin-Bond T, Boland P, Syros G, Kim YH, Gupta A, Mintz G, Fahy M, Collins M, Kodali S, Stone GW, Moses JW, Leon MB, Mehran R. Angiographic Patterns of Drug-Eluting Stent Restenosis and One-Year Outcomes After Treatment With Repeated Percutaneous Coronary Intervention. The American Journal Of Cardiology 2008, 102: 311-315. PMID: 18638592, DOI: 10.1016/j.amjcard.2008.03.060.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionMajor adverse cardiac eventsPatterns of ISRAdverse cardiac eventsTarget lesion revascularizationDES-ISRCoronary interventionPES-ISRCardiac eventsBalloon angioplastyStent restenosisDrug-eluting stent implantationColumbia University Medical CenterDES-ISR lesionsOne-year outcomesPaclitaxel-eluting stentsUnselected patient populationSirolimus-eluting stentsUniversity Medical CenterLow overall rateAngiographic patternsDES implantationDES placementISR lesionsConsecutive patients
2004
Gamma radiation for in‐stent restenosis: effect of lesion length on angiographic and clinical outcomes
Mehran R, Iakovou I, Dangas G, Lansky AJ, Stone GW, Mintz GS, Kent KM, Pichard AD, Satler LF, Fahy M, Leon MB, Waksman R. Gamma radiation for in‐stent restenosis: effect of lesion length on angiographic and clinical outcomes. Catheterization And Cardiovascular Interventions 2004, 61: 354-359. PMID: 14988895, DOI: 10.1002/ccd.10786.Peer-Reviewed Original ResearchConceptsISR groupLesion lengthClinical eventsIn-Stent Restenosis TrialBaseline lesion lengthLower late lossShort lesion groupTreatment of ISRStent restenosis lesionsLong-term outcomesRecurrent ISRRestenosis lesionsRestenosis TrialAngiographic outcomesISR lesionsRestenosis rateClinical outcomesWashington RadiationLate lossStent restenosisLumen dimensionsLong ISRRadiation treatmentPowerful predictorPatientsContribution of Stent Underexpansion to Recurrence After Sirolimus-Eluting Stent Implantation for In-Stent Restenosis
Fujii K, Mintz GS, Kobayashi Y, Carlier S, Takebayashi H, Yasuda T, Moussa I, Dangas G, Mehran R, Lansky AJ, Reyes A, Kreps E, Collins M, Colombo A, Stone GW, Teirstein PS, Leon MB, Moses JW. Contribution of Stent Underexpansion to Recurrence After Sirolimus-Eluting Stent Implantation for In-Stent Restenosis. Circulation 2004, 109: 1085-1088. PMID: 14993129, DOI: 10.1161/01.cir.0000121327.67756.19.Peer-Reviewed Original Research
2003
Intravascular brachytherapy for native coronary ostial in-stent restenotic lesions
Costantini CO, Lansky AJ, Mintz GS, Shirai K, Dangas G, Mehran R, Fahy M, Slack S, Coral M, Teirstein PS, Waksman R, Stone G, Moses J, Leon MB. Intravascular brachytherapy for native coronary ostial in-stent restenotic lesions. Journal Of The American College Of Cardiology 2003, 41: 1725-1731. PMID: 12767655, DOI: 10.1016/s0735-1097(03)00298-5.Peer-Reviewed Original ResearchConceptsAorto-ostial lesionsVascular brachytherapyRecurrence rateOstial ISRRestenosis rateStent restenosisBaseline lesion lengthStent restenotic lesionsHigh recurrence rateBinary restenosisPercutaneous reinterventionPlacebo patientsISR lesionsRestenotic lesionsQuantitative angiographyBeta patientsPatientsPooled databaseConventional treatmentRestenosisPlaceboLesionsLesion lengthBrachytherapySimilar reduction
2002
Late Vascular Response to Repeat Stenting for In-Stent Restenosis With and Without Radiation
Morino Y, Limpijankit T, Honda Y, Lansky AJ, Waksman R, Bonneau HN, Yock PG, Mintz GS, Fitzgerald PJ. Late Vascular Response to Repeat Stenting for In-Stent Restenosis With and Without Radiation. Circulation 2002, 105: 2465-2468. PMID: 12034650, DOI: 10.1161/01.cir.0000018949.39445.40.Peer-Reviewed Original ResearchMeSH KeywordsBlood Vessel Prosthesis ImplantationBrachytherapyCohort StudiesCoronary RestenosisDisease ProgressionDouble-Blind MethodFollow-Up StudiesGamma RaysHumansIridium RadioisotopesPlatelet Aggregation InhibitorsRandomized Controlled Trials as TopicRecurrenceReoperationStentsTiclopidineTimeTreatment OutcomeUltrasonography, InterventionalVascular PatencyConceptsLumen volume indexISR lesionsPlacebo patientsLate vascular responseAcute angiographic resultsIntravascular ultrasound analysisIn-Stent RestenosisPlacebo groupAngiographic resultsVascular responsesAdditional lumenNeointimal proliferationStent restenosisIrradiated groupPatientsStent overlapLesionsVolume indexUltrasound analysisSafety of radiationLong-term advantagesStent strutsSignificant decreaseStentingRestenosis
1999
Angiographic Patterns of In-Stent Restenosis
Mehran R, Dangas G, Abizaid A, Mintz G, Lansky A, Satler L, Pichard A, Kent K, Stone G, Leon M. Angiographic Patterns of In-Stent Restenosis. Circulation 1999, 100: 1872-1878. PMID: 10545431, DOI: 10.1161/01.cir.100.18.1872.Peer-Reviewed Original ResearchConceptsTarget vessel revascularizationRecurrent ISRAngiographic classificationStent restenosisSubsequent target vessel revascularizationClass IFinal diameter stenosisPattern IIPattern IVessel revascularizationAngiographic patternsISR lesionsIndependent predictorsDiameter stenosisPrognostic informationAngiographic presentationIntimal hyperplasiaPatient triageFocal lesionsIntravascular ultrasoundMultivariate analysisClass IIIPattern IVInvestigational purposesPattern III