2004
Randomized trial of Rotational Atherectomy Versus Balloon Angioplasty for Diffuse In-stent Restenosis (ROSTER)
Sharma SK, Kini A, Mehran R, Lansky A, Kobayashi Y, Marmur JD. Randomized trial of Rotational Atherectomy Versus Balloon Angioplasty for Diffuse In-stent Restenosis (ROSTER). American Heart Journal 2004, 147: 16-22. PMID: 14691413, DOI: 10.1016/j.ahj.2003.07.002.Peer-Reviewed Original ResearchConceptsTarget lesion revascularizationPrimary end pointDiffuse ISRPTCA groupBalloon angioplastyBalloon dilatationStent restenosisCoronary artery bypass graft proceduresIn-Stent Restenosis TrialStudy's primary end pointEnd pointHigh-pressure balloon dilatationRotational coronary atherectomySecondary end pointsBypass graft proceduresIntravascular ultrasound studyAcute luminal gainAdjunctive balloon dilatationIntimal hyperplasia areaAngiographic substudyAngiographic variablesLesion revascularizationRepeat stentingAngiographic restenosisAngiographic success
2001
Intravascular Ultrasound—Guided Renal Artery Stenting
Dangas G, Laird J, Mehran R, Lansky A, Mintz G, Leon M. Intravascular Ultrasound—Guided Renal Artery Stenting. Journal Of Endovascular Therapy 2001, 8: 238-247. PMID: 11491257, DOI: 10.1177/152660280100800302.Peer-Reviewed Original ResearchConceptsRenal arteryDiastolic arterial blood pressureLesion lengthHospital renal failureMean contrast volumePalmaz stent implantationRenal artery revascularizationRenal artery stentingStenotic renal arteriesArterial blood pressureIntravascular ultrasound guidanceMinimal luminal diameterProximal renal arteriesMajority of lesionsMean lesion lengthAntihypertensive medicationsArtery revascularizationTransient hemodialysisUncontrolled hypertensionAngiographic successRenal insufficiencyRenal failureSerum creatinineArtery stentingBlood pressureIntravascular Ultrasound–Guided Renal Artery Stenting
Dangas G, Laird J, Mehran R, Lansky A, Mintz G, Leon M. Intravascular Ultrasound–Guided Renal Artery Stenting. Journal Of Endovascular Therapy 2001, 8: 238-247. DOI: 10.1583/1545-1550(2001)008<0238:iugras>2.0.co;2.Peer-Reviewed Original ResearchRenal arteryDiastolic arterial blood pressureLesion lengthHospital renal failureMean contrast volumePalmaz stent implantationRenal artery revascularizationRenal artery stentingStenotic renal arteriesArterial blood pressureIntravascular ultrasound guidanceMinimal luminal diameterProximal renal arteriesMajority of lesionsMean lesion lengthAntihypertensive medicationsArtery revascularizationTransient hemodialysisUncontrolled hypertensionAngiographic successRenal insufficiencyRenal failureSerum creatinineArtery stentingBlood pressureTreatment of focal in-stent restenosis with balloon angioplasty alone versus stenting: Short- and long-term results
Mehran R, Dangas G, Abizaid A, Lansky A, Mintz G, Pichard A, Satler L, Kent K, Waksman R, Stone G, Leon M. Treatment of focal in-stent restenosis with balloon angioplasty alone versus stenting: Short- and long-term results. American Heart Journal 2001, 141: 610-614. PMID: 11275928, DOI: 10.1067/mhj.2001.113998.Peer-Reviewed Original ResearchConceptsPercutaneous transluminal coronary angioplastyMinimal lumen diameterLong-term clinical resultsFocal ISRStent groupClinical resultsStent restenosisLarger reference vessel diameterLesion lengthLesion revascularization rateTarget lesion revascularizationReference vessel diameterResidual diameter stenosisTransluminal coronary angioplastyLong-term resultsQ-wave infarctionPTCA groupUrgent revascularizationAngiographic successLesion revascularizationRevascularization ratesAdditional stentingBaseline characteristicsCoronary angioplastyDiabetic patients
2000
Treatment of In-Stent Restenosis With Excimer Laser Coronary Angioplasty Versus Rotational Atherectomy
Mehran R, Dangas G, Mintz G, Waksman R, Abizaid A, Satler L, Pichard A, Kent K, Lansky A, Stone G, Leon M. Treatment of In-Stent Restenosis With Excimer Laser Coronary Angioplasty Versus Rotational Atherectomy. Circulation 2000, 101: 2484-2489. PMID: 10831522, DOI: 10.1161/01.cir.101.21.2484.Peer-Reviewed Original ResearchConceptsExcimer laser coronary angioplastyVolumetric IVUS analysisRotational atherectomyQuantitative coronary angiographicClinical resultsCoronary angiographicIVUS analysisLumen enlargementSimilar long-term clinical outcomesTarget lesion revascularization rateLong-term clinical outcomesSignificant between-group differencesIntimal hyperplasia volumeLesion revascularization rateLaser coronary angioplastyTreatment of diffuseIn-Stent RestenosisSimilar clinical resultsBetween-group differencesIntravascular ultrasound measurementsAdjunct PTCADiffuse ISRHospital complicationsAngiographic successRevascularization ratesRandomized Trial of Contrast Media Utilization in High-Risk PTCA
Davidson C, Laskey W, Hermiller J, Harrison J, Matthai W, Vlietstra R, Brinker J, Kereiakes D, Muhlestein J, Lansky A, Popma J, Buchbinder M, Hirshfeld J. Randomized Trial of Contrast Media Utilization in High-Risk PTCA. Circulation 2000, 101: 2172-2177. PMID: 10801758, DOI: 10.1161/01.cir.101.18.2172.Peer-Reviewed Original ResearchConceptsMajor adverse clinical eventsHospital major adverse clinical eventsPrimary end pointClinical eventsNonionic dimer iodixanolDimer iodixanolEnd pointLow-osmolar contrast agentsHigh-risk PTCAHospital clinical eventsThrombus-related eventsTotal clinical eventsDouble-blind trialAcute coronary syndromeHigh-risk patientsProspective multicenter trialAdverse clinical eventsCoronary artery interventionPTCA outcomeAngiographic successCoronary syndromeNovo lesionsArtery interventionMulticenter trialRandomized trials
1999
Preintervention Arterial Remodeling as an Independent Predictor of Target-Lesion Revascularization After Nonstent Coronary Intervention
Dangas G, Mintz G, Mehran R, Lansky A, Kornowski R, Pichard A, Satler L, Kent K, Stone G, Leon M. Preintervention Arterial Remodeling as an Independent Predictor of Target-Lesion Revascularization After Nonstent Coronary Intervention. Circulation 1999, 99: 3149-3154. PMID: 10377078, DOI: 10.1161/01.cir.99.24.3149.Peer-Reviewed Original ResearchConceptsIndependent predictorsArterial remodelingTarget lesion revascularization rateInsulin-dependent diabetic patientsLong-term clinical outcomesQ-wave myocardial infarctionMultivariable logistic regression analysisTarget lesion revascularizationShort-term complicationsIntravascular ultrasound studyLong-term outcomesFinal lumen areaLogistic regression analysisIntermediate remodelingAngiographic characteristicsAngiographic successRevascularization ratesCoronary interventionClinical outcomesDiabetic patientsPlaque burdenPositive remodelingMyocardial infarctionNegative remodelingPercutaneous intervention
1996
Angiographic and Clinical Outcome after Cutting Balloon Angioplasty.
Popma J, Lansky A, Purkayastha D, Hall L, Bonan R. Angiographic and Clinical Outcome after Cutting Balloon Angioplasty. Journal Of Invasive Cardiology 1996, 8 Suppl A: 12a-19a. PMID: 10785760.Peer-Reviewed Original ResearchBalloon angioplastyConventional balloon angioplastyResidual stenosisClinical outcomesBalloon useDiameter stenosisArtery ratioNon-complex coronary artery diseaseComplex coronary artery diseaseCutting Balloon AngioplastyReference artery sizeCoronary artery diseaseMinimal lumen diameterCore laboratory analysisPrevention of restenosisAngiographic core laboratory analysisNew device angioplastyHospital complicationsOstial locationAngiographic successArtery diseaseConsecutive patientsArtery sizeSignificant inverse relationshipMorphologic findings