2023
Evidence of leaky protection following COVID-19 vaccination and SARS-CoV-2 infection in an incarcerated population
Lind M, Dorion M, Houde A, Lansing M, Lapidus S, Thomas R, Yildirim I, Omer S, Schulz W, Andrews J, Hitchings M, Kennedy B, Richeson R, Cummings D, Ko A. Evidence of leaky protection following COVID-19 vaccination and SARS-CoV-2 infection in an incarcerated population. Nature Communications 2023, 14: 5055. PMID: 37598213, PMCID: PMC10439918, DOI: 10.1038/s41467-023-40750-8.Peer-Reviewed Original ResearchConceptsSARS-CoV-2 infectionPrior infectionHybrid immunityInfection riskCOVID-19 vaccinationNon-pharmaceutical interventionsInfected residentsVaccinationInfectionDocumented exposureDelta periodCell exposureIncarcerated populationsExposureImmunityRiskAssociationPotential benefitsCorrectional facilitiesCrowded settingsResidentsPeriod
2022
Use of Recently Vaccinated Individuals to Detect Bias in Test-Negative Case–Control Studies of COVID-19 Vaccine Effectiveness
Hitchings MDT, Lewnard JA, Dean NE, Ko AI, Ranzani OT, Andrews JR, Cummings DAT. Use of Recently Vaccinated Individuals to Detect Bias in Test-Negative Case–Control Studies of COVID-19 Vaccine Effectiveness. Epidemiology 2022, 33: 450-456. PMID: 35384900, PMCID: PMC9148635, DOI: 10.1097/ede.0000000000001484.Peer-Reviewed Original ResearchConceptsCOVID-19 vaccine effectivenessVaccine effectivenessNegative control exposureObservational studyControl exposurePhase III trialsTest-negative studiesTest-negative casesVaccine effectiveness estimatesCOVID-19 vaccineDemonstration of efficacyCOVID-19 riskIII trialsUnvaccinated individualsClinical trialsControl studyStudy designEffectiveness estimatesCareful study designUnmeasured confoundingSelection biasTrialsConfoundingExposureIndividuals