Leptomeningeal disease: current diagnostic and therapeutic strategies
Nayar G, Ejikeme T, Chongsathidkiet P, Elsamadicy AA, Blackwell KL, Clarke JM, Lad SP, Fecci PE. Leptomeningeal disease: current diagnostic and therapeutic strategies. Oncotarget 2017, 5: 73312-73328. PMID: 29069871, PMCID: PMC5641214, DOI: 10.18632/oncotarget.20272.Peer-Reviewed Original ResearchLeptomeningeal diseaseT1-weighted magnetic resonance imagingCerebrospinal fluid cytologyLate-stage complicationsNovel therapeutic interventionsMagnetic resonance imagingLeptomeningeal spreadMedian survivalNeurological deficitsPrimary malignancyObstructive hydrocephalusSystemic diseaseCancer patientsLung cancerTreatment modalitiesFluid cytologyBreast cancerRadiation therapyTherapeutic strategiesTherapeutic interventionsMalignant cellsResonance imagingYounger ageEarly detectionDisease