2023
Novel Standalone Motion-Sparing Pelvic Fixation Prevents Short-Term Insufficiency Fractures After Midsacrectomies Without Sacrificing Normal, Mobile Lumbar Segments Traditionally Used for Stabilization
Lo S, Pieters T, Hersh A, Green R, Suk I, Pennington Z, Elsamadicy A, Sciubba D. Novel Standalone Motion-Sparing Pelvic Fixation Prevents Short-Term Insufficiency Fractures After Midsacrectomies Without Sacrificing Normal, Mobile Lumbar Segments Traditionally Used for Stabilization. Operative Neurosurgery 2023, 25: 278-284. PMID: 37278692, DOI: 10.1227/ons.0000000000000767.Peer-Reviewed Original ResearchConceptsSacral insufficiency fracturesMobile lumbar segmentsInsufficiency fracturesPelvic fixationPartial sacrectomyLumbar segmentsMedian age 59 yearsPrimary malignant bone tumorAge 59 yearsTreatment of choiceMalignant bone tumorsComprehensive cancer centerRetrospective data setConcomitant placementAdverse eventsOverall survivalPrimary outcomeSacral tumorsHistorical cohortMobile spineRetrospective studyCancer CenterLumbopelvic fixationOperative characteristicsBone tumors
2021
Systematic review of charged-particle therapy for chordomas and sarcomas of the mobile spine and sacrum.
Pennington Z, Ehresman J, Elsamadicy AA, Shin JH, Goodwin CR, Schwab JH, Sciubba DM. Systematic review of charged-particle therapy for chordomas and sarcomas of the mobile spine and sacrum. Neurosurgical FOCUS 2021, 50: e17. PMID: 33932924, DOI: 10.3171/2021.2.focus201059.Peer-Reviewed Original ResearchConceptsDisease-free survivalProgression-free survivalDisease-specific survivalOverall survivalLocal controlMobile spineLong-term local controlAcute toxicityManagement of sarcomasEn bloc resectionCharged-particle therapyUse of protonsFull-text screeningDefinitive radiotherapyAdjuvant radiationDefinitive radiationSurgical cohortSurgical groupPrimary sarcomaUnresectable tumorsBloc resectionNegative marginsRadiation toxicityConventional radiotherapyHigh risk