2024
167 Association Between Safety-net Hospital Status and Postoperative Outcomes Following ACDF or PCDF for Cervical Spondylotic Myelopathy
Elsamadicy A, Sayeed S, Craft S, Sherman J, Reeves B, Koo A, Khalid S, Lo S, Shin J, Mendel E, Sciubba D. 167 Association Between Safety-net Hospital Status and Postoperative Outcomes Following ACDF or PCDF for Cervical Spondylotic Myelopathy. Neurosurgery 2024, 70: 40-40. DOI: 10.1227/neu.0000000000002809_167.Peer-Reviewed Original ResearchCervical spondylotic myelopathyNon-routine dischargeSafety-net hospital statusSafety-net hospitalACDF cohortSpondylotic myelopathyPostoperative outcomesAdverse eventsMultivariate analysisPosterior cervical decompressionAnterior cervical discectomyImpact postoperative outcomesProportion of patientsNational Inpatient Sample databaseRetrospective cohort studyPredictors of prolonged LOSInpatient Sample databaseNon-SNHsElective ACDFCervical decompressionCervical discectomyStudy patientsIndependent predictorsAdult patientsACDFReduced racial disparities among newborns with intraventricular hemorrhage
Sayeed S, Reeves B, Theriault B, Hengartner A, Ahsan N, Sadeghzadeh S, Elsamadicy E, DiLuna M, Elsamadicy A. Reduced racial disparities among newborns with intraventricular hemorrhage. Child's Nervous System 2024, 40: 2051-2059. PMID: 38526575, DOI: 10.1007/s00381-024-06369-w.Peer-Reviewed Original ResearchLength of stayIntroductionIntraventricular hemorrhageAdverse eventsMultivariate logistic regression analysisRate of adverse eventsPermanent neurological dysfunctionProlonged length of stayNational Inpatient Sample databaseRates of NECInpatient Sample databaseLogistic regression analysisIntraventricular hemorrhageAA patientsImpact of raceCost of admissionIndependent predictorsRate of mortalityPatient characteristicsMultivariate analysisPercentage of AAWhite patientsNeurological dysfunctionNewbornsPatient genderPatients
2023
Influence of affective disorders on outcomes after suboccipital decompression for adult Chiari I malformation
Sherman J, Sayeed S, Craft S, Reeves B, Hengartner A, Fernandez T, Koo A, DiLuna M, Elsamadicy A. Influence of affective disorders on outcomes after suboccipital decompression for adult Chiari I malformation. Clinical Neurology And Neurosurgery 2023, 236: 108104. PMID: 38171050, DOI: 10.1016/j.clineuro.2023.108104.Peer-Reviewed Original ResearchHealthcare resource utilizationNon-routine dischargeLength of stayChiari I malformationAD cohortSuboccipital decompressionAffective disordersAdverse eventsPatient demographicsPostoperative eventsAdmission costsExtended LOSMean LOSNational Inpatient Sample databaseMultivariate logistic regression analysisAdult Chiari I malformationIncidence of syringomyeliaPerioperative adverse eventsChronic pulmonary diseaseICD-10-CM codesGreater proportionLogistic regression analysisComorbid affective disordersAdult patientsIndependent predictorsImpact of Preoperative Frailty on Outcomes in Patients with Cervical Spondylotic Myelopathy Undergoing Anterior vs. Posterior Cervical Surgery
Elsamadicy A, Sayeed S, Sherman J, Craft S, Reeves B, Lo S, Shin J, Sciubba D. Impact of Preoperative Frailty on Outcomes in Patients with Cervical Spondylotic Myelopathy Undergoing Anterior vs. Posterior Cervical Surgery. Journal Of Clinical Medicine 2023, 13: 114. PMID: 38202121, PMCID: PMC10779741, DOI: 10.3390/jcm13010114.Peer-Reviewed Original ResearchNon-routine dischargeHealthcare resource utilizationAdverse eventsHealth care utilizationFrail patientsIndependent predictorsPreoperative frailtySevere frailtyExtended LOSCare utilizationFrail cohortIncidence of AEsGreater health care utilizationMultivariate logistic regression analysisMore frail patientsPosterior cervical decompressionRetrospective cohort studyAnterior cervical discectomyPerioperative adverse eventsAdditional prospective studiesNational Inpatient SamplePosterior cervical surgeryLogistic regression analysisHigh rateCervical decompressionRacial/Ethnic Disparities Among Patients Undergoing Anterior Cervical Discectomy and Fusion or Posterior Cervical Decompression and Fusion for Cervical Spondylotic Myelopathy: A National Administrative Database Analysis
Elsamadicy A, Sayeed S, Sherman J, Craft S, Reeves B, Hengartner A, Koo A, Larry Lo S, Shin J, Mendel E, Sciubba D. Racial/Ethnic Disparities Among Patients Undergoing Anterior Cervical Discectomy and Fusion or Posterior Cervical Decompression and Fusion for Cervical Spondylotic Myelopathy: A National Administrative Database Analysis. World Neurosurgery 2023, 183: e372-e385. PMID: 38145651, DOI: 10.1016/j.wneu.2023.12.103.Peer-Reviewed Original ResearchCervical spondylotic myelopathyNon-routine dischargeHealthcare resource utilizationExtended hospital LOSHospital LOSWhite patientsHispanic patientsPatient raceNational Inpatient Sample databaseMultivariate logistic regression analysisGreater comorbidity burdenRacial/Ethnic DisparitiesAdministrative database analysisLogistic regression analysisRace/ethnicityACDF cohortComorbidity burdenPostoperative complicationsAdult patientsAdverse eventsPatient demographicsSpondylotic myelopathyIndependent predictorsSurgical outcomesBlack raceAssociated Risk Factors for Extended Operative Time Following Cranial Vault Remodeling for Craniosynostosis: Analysis of the 2012 to 2021 NSQIP-Pediatric Database
Serrato P, Hengartner A, Sayeed S, Prassinos A, Alperovich M, DiLuna M, Elsamadicy A. Associated Risk Factors for Extended Operative Time Following Cranial Vault Remodeling for Craniosynostosis: Analysis of the 2012 to 2021 NSQIP-Pediatric Database. Journal Of Craniofacial Surgery 2023, 35: 427-431. PMID: 38078913, DOI: 10.1097/scs.0000000000009920.Peer-Reviewed Original ResearchExtended operative timeCranial vault remodelingRetrospective cohort studyAdverse eventsCohort studyIndependent predictorsPediatric patientsOperative timeRisk factorsVault remodelingNational Surgical Quality Improvement Program-PediatricHealth care resource utilizationPostoperative surgical site infectionSurgeons National Surgical Quality Improvement Program-PediatricMultivariate logistic regression analysisDiseases 9/10 codesNSQIP-Pediatric databasePostoperative adverse eventsHigher American SocietySurgical site infectionAssociated risk factorsSurgical adverse eventsLength of stayLogistic regression analysisNon-Hispanic whitesImplications of Frailty on Postoperative Health Care Resource Utilization in Ankylosing Spondylitis Patients Undergoing Spine Surgery for Spinal Fractures
Elsamadicy A, Sayeed S, Sadeghzadeh S, Reeves B, Sherman J, Craft S, Serrato P, Larry Lo S, Sciubba D. Implications of Frailty on Postoperative Health Care Resource Utilization in Ankylosing Spondylitis Patients Undergoing Spine Surgery for Spinal Fractures. World Neurosurgery 2023, 182: e16-e28. PMID: 37925147, DOI: 10.1016/j.wneu.2023.10.136.Peer-Reviewed Original ResearchNon-routine dischargeExtended hospital stayIndependent predictorsHospital stayAdverse eventsModified Frailty Index scoreNational Inpatient Sample databaseMultivariate logistic regression analysisFrailty index scoreHealthcare resource utilizationNumber of comorbiditiesHigher hospital costsPosterior spinal fusionCost of admissionImplications of frailtyLogistic regression analysisMultiple adverse eventsHealth care costsQuality patient careGreater comorbidityAdult patientsSpondylitis patientsElective surgeryRetrospective studySurgical outcomesAssessment of the impact of frailty on adverse surgical outcomes in patients undergoing surgery for intracranial tumors using modified frailty index: A systematic review and meta-analysis
Aghajanian S, Shafiee A, Ahmadi A, Elsamadicy A. Assessment of the impact of frailty on adverse surgical outcomes in patients undergoing surgery for intracranial tumors using modified frailty index: A systematic review and meta-analysis. Journal Of Clinical Neuroscience 2023, 114: 120-128. PMID: 37390775, DOI: 10.1016/j.jocn.2023.06.013.Peer-Reviewed Original ResearchConceptsImpact of frailtyFrailty indexMFI scoreAdverse outcomesReoperation rateIntracranial tumorsNon-frail participantsAdverse surgical outcomesNeuro-oncological surgeryWeb of SciencePerioperative outcomesComplication rateIndependent predictorsSurgical outcomesWorse prognosisMean ageObservational studySurgical pathologyMixed-effects multilevel modelsPrimary analysisSystematic reviewNeurosurgical proceduresFrailtySurgical operationSurgeryDifferences in Outcomes and Health Care Resource Utilization After Surgical Intervention for Metastatic Spinal Column Tumor in Safety-Net Hospitals
Elsamadicy A, Koo A, David W, Reeves B, Sherman J, Craft S, Hersh A, Duvall J, Lo S, Shin J, Mendel E, Sciubba D. Differences in Outcomes and Health Care Resource Utilization After Surgical Intervention for Metastatic Spinal Column Tumor in Safety-Net Hospitals. Spine 2023, 48: 800-809. PMID: 36972069, DOI: 10.1097/brs.0000000000004643.Peer-Reviewed Original ResearchConceptsSpinal column tumorsSNH statusPostoperative complicationsDischarge dispositionMultivariable analysisTumor surgeryMetastatic spinal tumor surgeryHealth care resource utilizationNationwide Inpatient Sample databaseICD-10-CM codingNonroutine discharge dispositionObservational cohort studySpinal tumor surgerySafety-net hospitalNonroutine dischargeSNH patientsHospital lengthStudy patientsAdult patientsCohort studyIntraoperative variablesExtended LOSIndependent predictorsLonger LOSProlonged hospitalization
2022
Utilization of Machine Learning to Model Important Features of 30-day Readmissions following Surgery for Metastatic Spinal Column Tumors: The Influence of Frailty
Elsamadicy A, Koo A, Reeves B, Cross J, Hersh A, Hengartner A, Karhade A, Pennington Z, Akinduro O, Lo S, Gokaslan Z, Shin J, Mendel E, Sciubba D. Utilization of Machine Learning to Model Important Features of 30-day Readmissions following Surgery for Metastatic Spinal Column Tumors: The Influence of Frailty. Global Spine Journal 2022, 14: 1227-1237. PMID: 36318478, PMCID: PMC11289550, DOI: 10.1177/21925682221138053.Peer-Reviewed Original ResearchHospital Frailty Risk ScoreSpinal column tumorsFrailty Risk ScoreInfluence of frailtySpinal column metastasesProportion of patientsRetrospective cohort studyNationwide Readmissions DatabaseRisk of readmissionMultivariate regression analysisIntermediate frailtyAdult patientsCohort studyIndependent predictorsSurgical interventionSpine surgeryReadmissionPatient readmissionRisk scorePatientsFrailtySurgeryCohortTumorsRegression analysisHospital Frailty Risk Score Predicts Adverse Events and Readmission Following a Ventriculoperitoneal Shunt Surgery for Normal Pressure Hydrocephalus
Koo AB, Elsamadicy AA, Renedo D, Sarkozy M, Reeves BC, Barrows MM, Hengartner A, Havlik J, Sandhu MRS, Antonios JP, Malhotra A, Matouk CC. Hospital Frailty Risk Score Predicts Adverse Events and Readmission Following a Ventriculoperitoneal Shunt Surgery for Normal Pressure Hydrocephalus. World Neurosurgery 2022, 170: e9-e20. PMID: 35970293, DOI: 10.1016/j.wneu.2022.08.037.Peer-Reviewed Original ResearchConceptsHospital Frailty Risk ScoreFrailty Risk ScoreVP shunt surgeryVentriculoperitoneal shunt surgeryAdverse eventsShunt surgeryIndependent predictorsNPH patientsRisk scoreHealth care resource utilizationMultivariate logistic regression analysisNormal pressure hydrocephalus patientsRetrospective cohort studyNationwide Readmissions DatabaseNormal pressure hydrocephalusLogistic regression analysisRegression analysisMultivariate regression analysisUnplanned readmissionCohort studyHospital readmissionPressure hydrocephalusAdmission costsReadmissionHydrocephalus patientsAssessment of Frailty Indices and Charlson Comorbidity Index for Predicting Adverse Outcomes in Patients Undergoing Surgery for Spine Metastases: A National Database Analysis
Elsamadicy AA, Havlik JL, Reeves B, Sherman J, Koo AB, Pennington Z, Hersh AM, Sandhu MRS, Kolb L, Larry Lo SF, Shin JH, Mendel E, Sciubba DM. Assessment of Frailty Indices and Charlson Comorbidity Index for Predicting Adverse Outcomes in Patients Undergoing Surgery for Spine Metastases: A National Database Analysis. World Neurosurgery 2022, 164: e1058-e1070. PMID: 35644519, DOI: 10.1016/j.wneu.2022.05.101.Peer-Reviewed Original ResearchConceptsMetastatic spinal tumor frailty indexCharlson Comorbidity IndexFrailty indexMFI-5Adverse outcomesNonroutine dischargeComorbidity indexUnplanned readmissionAdverse eventsNational Surgical Quality Improvement Program databaseHigher Charlson comorbidity indexQuality Improvement Program databaseMultivariate logistic regression analysisPredicting Adverse OutcomesRetrospective cohort studyImprovement Program databaseNational database analysisLength of stayLogistic regression analysisExtradural spinal metastasisOnly significant predictorAdult patientsCohort studyProlonged lengthIndependent predictorsA novel online calculator to predict nonroutine discharge, length of stay, readmission, and reoperation in patients undergoing surgery for intramedullary spinal cord tumors
Hersh AM, Patel J, Pennington Z, Antar A, Goldsborough E, Porras JL, Feghali J, Elsamadicy AA, Lubelski D, Wolinsky JP, Jallo GI, Gokaslan ZL, Lo SL, Sciubba DM. A novel online calculator to predict nonroutine discharge, length of stay, readmission, and reoperation in patients undergoing surgery for intramedullary spinal cord tumors. The Spine Journal 2022, 22: 1345-1355. PMID: 35342014, DOI: 10.1016/j.spinee.2022.03.005.Peer-Reviewed Original ResearchConceptsIntramedullary spinal cord tumorsModified McCormick ScaleSpinal cord tumorsNonroutine dischargeDay readmissionIndependent predictorsWeb-based calculatorBowel dysfunctionNonhome dischargePatient demographicsCord tumorsIncision lengthHigher preoperative white blood cell countResection of ISCTsPreoperative white blood cell countStepwise multivariable logistic regression modelSingle comprehensive cancer centerWhite blood cell countMultivariable logistic regression modelRetrospective cohort study PATIENT SAMPLEBaseline neurological statusDays unplanned readmissionLonger incision lengthNovel online calculatorPreoperative neurological symptomsImpact of Frailty on Morbidity and Mortality in Adult Patients Undergoing Surgical Evacuation of Acute Traumatic Subdural Hematoma
Elsamadicy AA, Sandhu MRS, Freedman IG, Koo AB, Reeves BC, Yu J, Hengartner A, Havlik J, Hong CS, Rutherford HJV, Kim JA, Gerrard J, Gilmore EJ, Omay SB. Impact of Frailty on Morbidity and Mortality in Adult Patients Undergoing Surgical Evacuation of Acute Traumatic Subdural Hematoma. World Neurosurgery 2022, 162: e251-e263. PMID: 35276399, DOI: 10.1016/j.wneu.2022.02.122.Peer-Reviewed Original ResearchConceptsAcute traumatic subdural hematomaTraumatic subdural hematomaHospital mortalityNonroutine dischargeSubdural hematomaExtended LOSIndependent predictorsAdult patientsBaseline frailtyMultivariate logistic regression analysisExtended hospital lengthImpact of frailtyRetrospective cohort studyNational Trauma DatabaseLogistic regression analysisRegression analysisMultivariate regression analysisHealth care expendituresFrail patientsHospital lengthCohort studySurgical evacuationFrailty indexTrauma databasePatients464 Hospital Frailty Risk Score and Healthcare Resource Utilization After Surgery for Metastatic Spinal Column Tumors
Elsamadicy A, Koo A, Reeves B, Pennington Z, Yu J, Goodwin C, Kolb L, Laurans M, Lo S, Shin J, Sciubba D. 464 Hospital Frailty Risk Score and Healthcare Resource Utilization After Surgery for Metastatic Spinal Column Tumors. Neurosurgery 2022, 68: 113-113. DOI: 10.1227/neu.0000000000001880_464.Peer-Reviewed Original ResearchHospital Frailty Risk ScoreNon-routine dischargeFrailty Risk ScoreSpinal column tumorsPatient populationRisk scoreLarge national database studyNational Inpatient Sample databaseMultivariate logistic regression analysisICD-10 diagnostic codesProlonged hospital LOSImpact of frailtyNational database studyHealthcare resource utilizationRetrospective cohort studyTotal hospital costsProcedural Coding SystemLogistic regression analysisRegression analysisMultivariate regression analysisHospital LOSCohort studyHospital admissionIndependent predictorsLonger LOS356 Patient-and-Hospital-Related Risk Factors for Non-Routine Discharge After Lumbar Decompression and Fusion for Spondylolisthesis
Elsamadicy A, Freedman I, Koo A, David W, Hengartner A, Havlik J, Hersh A, Pennington Z, Kolb L, Laurans M, Shin J, Sciubba D. 356 Patient-and-Hospital-Related Risk Factors for Non-Routine Discharge After Lumbar Decompression and Fusion for Spondylolisthesis. Neurosurgery 2022, 68: 84-84. DOI: 10.1227/neu.0000000000001880_356.Peer-Reviewed Original ResearchNon-routine dischargeSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseNon-Hispanic black race/ethnicityQuality Improvement Program databaseICD-9-CM diagnosisBlack race/ethnicityMultivariate logistic regression modelDependent functional statusImprovement Program databaseRetrospective cohort studyProcedural Coding SystemQuality of careMultivariate regression analysisPaucity of dataLogistic regression modelsRace/ethnicityUnplanned readmissionCohort studyDischarge dispositionReadmission ratesAdult patientsAdverse eventsIndependent predictorsLonger LOSDifferences in Health Care Resource Utilization After Surgery for Metastatic Spinal Column Tumors in Patients with a Concurrent Affective Disorder in the United States
Elsamadicy AA, Koo AB, Sarkozy M, Reeves BC, Pennington Z, Havlik J, Sandhu MR, Hersh A, Patel S, Kolb L, Larry Lo SF, Shin JH, Mendel E, Sciubba DM. Differences in Health Care Resource Utilization After Surgery for Metastatic Spinal Column Tumors in Patients with a Concurrent Affective Disorder in the United States. World Neurosurgery 2022, 161: e252-e267. PMID: 35123021, DOI: 10.1016/j.wneu.2022.01.112.Peer-Reviewed Original ResearchConceptsLength of stayHealth care resource utilizationPostoperative adverse eventsNonroutine dischargeAdverse eventsAffective disordersNational Inpatient Sample databaseMultivariate logistic regression analysisSpinal column metastasesRetrospective cohort studyMetastatic spinal tumorsSpinal column tumorsLogistic regression analysisConcurrent affective disorderGreater total costsRegression analysisMultivariate regression analysisAdult patientsCohort studyDischarge dispositionIntraoperative variablesPatient demographicsHospital admissionIndependent predictorsSpinal metastases
2021
Comparison of frailty metrics and the Charlson Comorbidity Index for predicting adverse outcomes in patients undergoing surgery for spine metastases.
Hersh AM, Pennington Z, Hung B, Patel J, Goldsborough E, Schilling A, Feghali J, Antar A, Srivastava S, Botros D, Elsamadicy AA, Lo SL, Sciubba DM. Comparison of frailty metrics and the Charlson Comorbidity Index for predicting adverse outcomes in patients undergoing surgery for spine metastases. Journal Of Neurosurgery Spine 2021, 36: 849-857. PMID: 34826820, DOI: 10.3171/2021.8.spine21559.Peer-Reviewed Original ResearchMetastatic spinal tumor frailty indexCharlson Comorbidity IndexLength of stayNonroutine dischargePostoperative complicationsMFI-5Frailty metricsComorbidity indexPostoperative outcomesFrailty indexSpine metastasis patientsAdverse postoperative outcomesPatient demographic characteristicsProspective multicenter cohortHigh complication rateComprehensive cancer centerRobust independent predictorOutcomes of interestMedical comorbiditiesMetastasis surgeryPostoperative morbidityComplication rateMetastasis patientsRetrospective cohortIndependent predictorsImpact of race on nonroutine discharge, length of stay, and postoperative complications after surgery for spinal metastases.
Hung B, Pennington Z, Hersh AM, Schilling A, Ehresman J, Patel J, Antar A, Porras JL, Elsamadicy AA, Sciubba DM. Impact of race on nonroutine discharge, length of stay, and postoperative complications after surgery for spinal metastases. Journal Of Neurosurgery Spine 2021, 36: 678-685. PMID: 34740176, DOI: 10.3171/2021.7.spine21287.Peer-Reviewed Original ResearchConceptsLow preoperative KPS scoreNonroutine dischargePreoperative KPS scoreSpinal metastasesInsurance statusPostoperative complicationsKPS scoreIndependent predictorsFunctional statusPreoperative Karnofsky Performance Scale scoreHigher Charlson comorbidity indexSingle comprehensive cancer centerKarnofsky Performance Scale scoreStepwise multivariable logistic regressionFrankel grade ANonhome discharge destinationCharlson Comorbidity IndexPreoperative clinical characteristicsPrimary tumor typeBaseline functional statusMultivariable logistic regressionMarital statusLength of stayPerformance Scale scoreComprehensive cancer centerPatient- and hospital-related risk factors for non-routine discharge after lumbar decompression and fusion for spondylolisthesis
Elsamadicy AA, Freedman IG, Koo AB, David W, Hengartner AC, Havlik J, Reeves BC, Hersh A, Pennington Z, Kolb L, Laurans M, Shin JH, Sciubba DM. Patient- and hospital-related risk factors for non-routine discharge after lumbar decompression and fusion for spondylolisthesis. Clinical Neurology And Neurosurgery 2021, 209: 106902. PMID: 34481141, DOI: 10.1016/j.clineuro.2021.106902.Peer-Reviewed Original ResearchConceptsNon-routine dischargeDependent functional statusAdverse eventsIndependent predictorsUnplanned readmissionLonger LOSSpinal decompressionLumbar spondylolisthesisFemale sexFunctional statusSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseNon-Hispanic black race/ethnicityHospital-related risk factorsQuality Improvement Program databaseNon-Hispanic black raceICD-9-CM diagnosisBlack race/ethnicityMultivariate logistic regression modelNon-home dischargeHospital-related factorsImprovement Program databaseRetrospective cohort studyLength of stayProcedural Coding System