2021
Perioperative thrombocytopenia
Lombard FW, Popescu WM, Oprea AD, Kertai MD. Perioperative thrombocytopenia. Current Opinion In Anaesthesiology 2021, 34: 335-344. PMID: 33935182, DOI: 10.1097/aco.0000000000000999.Peer-Reviewed Original ResearchConceptsPlatelet countThrombopoietin receptor agonistsRisk of bleedingProphylactic platelet transfusionsProthrombin complex concentrateRecombinant factor VIIGood quality evidenceThreshold platelet countIntravenous immunoglobulinPreoperative thrombocytopeniaAsymptomatic patientsPerioperative strategiesPerioperative managementSevere bleedingAntifibrinolytic agentsPlatelet transfusionsComplex concentrateQuality evidenceFibrinogen levelsReceptor agonistPerioperative thrombocytopeniaPlatelet functionThrombin generationIntraoperative alternativeFactor VII
2013
P2Y12 Receptor Inhibitors in Acute Coronary Syndromes: What Is New on the Horizon?
Oprea AD, Popescu WM. P2Y12 Receptor Inhibitors in Acute Coronary Syndromes: What Is New on the Horizon? Cardiology Research And Practice 2013, 2013: 195456. PMID: 23533940, PMCID: PMC3590496, DOI: 10.1155/2013/195456.Peer-Reviewed Original ResearchAcute coronary syndromeP2Y12 receptor inhibitorsPercutaneous coronary interventionPlatelet function testingCoronary syndromeReceptor inhibitorsAntiplatelet therapyCoronary interventionFunction testingDual antiplatelet therapySubsequent ischemic eventsHigh-risk patientsEffective antiplatelet agentCornerstone therapyIschemic eventsAntiplatelet agentsPharmacodynamic interactionsPlatelet inhibitionPercutaneous interventionPharmacogenomic factorsPlatelet functionCare assaysRoutine usePatientsSyndrome