MR Perfusion in the Evaluation of Mechanical Thrombectomy Candidacy
Muddasani V, de Havenon A, McNally JS, Baradaran H, Alexander MD. MR Perfusion in the Evaluation of Mechanical Thrombectomy Candidacy. Topics In Magnetic Resonance Imaging 2021, 30: 197-204. PMID: 34397969, PMCID: PMC8371677, DOI: 10.1097/rmr.0000000000000277.Peer-Reviewed Original ResearchConceptsMagnetic resonance imagingIschemic strokeComputed tomographyMR perfusionCore infarctDiffusion-weighted magnetic resonance imagingPerfusion-diffusion mismatchDegree of ischemiaNoncontrast Computed TomographyImproved imaging techniquesSalvageable brainSuperior diagnostic informationIschemic penumbraSymptom onsetAcute evaluationAppropriate imagingPatient selectionStroke therapyThrombolytic therapyPoor outcomePrognostic valueLeading causeEffective treatmentBetter outcomesEarly identificationPredicting neuroimaging eligibility for extended-window endovascular thrombectomy.
de Havenon A, Mickolio K, O'Donnell S, Stoddard G, McNally JS, Alexander M, Taussky P, Awad AW. Predicting neuroimaging eligibility for extended-window endovascular thrombectomy. Journal Of Neurosurgery 2021, 135: 1100-1104. PMID: 33636705, PMCID: PMC8387497, DOI: 10.3171/2020.8.jns20386.Peer-Reviewed Original ResearchLarge vessel occlusionAlberta Stroke Program Early CT ScoreTissue plasminogen activatorEndovascular thrombectomyC-statisticPatients 5Stroke patientsTreatment windowFurther patient careHealth Stroke ScaleIschemic stroke treatmentLarge patient registriesSecond outcomePatients 4.5Stroke ScaleAdvanced imaging toolsStroke treatmentSalvageable penumbraCT scorePatient eligibilityClinical variablesPatient RegistryMultivariable modelMR perfusionTreatment cutoff