2016
Patterns of Genome-Wide Variation in Glossina fuscipes fuscipes Tsetse Flies from Uganda
Gloria-Soria A, Dunn WA, Telleria EL, Evans BR, Okedi L, Echodu R, Warren WC, Montague MJ, Aksoy S, Caccone A. Patterns of Genome-Wide Variation in Glossina fuscipes fuscipes Tsetse Flies from Uganda. G3: Genes, Genomes, Genetics 2016, 6: 1573-1584. PMID: 27172181, PMCID: PMC4889654, DOI: 10.1534/g3.116.027235.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsChromosome MappingDNA, MitochondrialGene-Environment InteractionGenes, InsectGenetic LinkageGenetic VariationGenetics, PopulationGenome, InsectGenome-Wide Association StudyGenomicsGenotypeGeographyHigh-Throughput Nucleotide SequencingLinkage DisequilibriumMicrosatellite RepeatsPolymorphism, Single NucleotideSelection, GeneticTsetse FliesUgandaConceptsSingle nucleotide polymorphismsLinkage disequilibriumExtent of LDLocal environmental adaptationGenome-wide variationDetection of lociOverall linkage disequilibriumInsect vectorsDifferent environmental conditionsWhole-genome sequencingPopulation genomicsStrong selectionAssociation analysisEnvironmental adaptationGenomic patternsPopulation dynamicsSignificant genetic associationUninfected fliesDisease transmissionSequence technologyAssociation studiesEnvironmental conditionsTsetse fliesHuman African trypanosomiasisRelevant phenotypes
2013
Wolbachia association with the tsetse fly, Glossina fuscipes fuscipes, reveals high levels of genetic diversity and complex evolutionary dynamics
Symula RE, Alam U, Brelsfoard C, Wu Y, Echodu R, Okedi LM, Aksoy S, Caccone A. Wolbachia association with the tsetse fly, Glossina fuscipes fuscipes, reveals high levels of genetic diversity and complex evolutionary dynamics. BMC Ecology And Evolution 2013, 13: 31. PMID: 23384159, PMCID: PMC3574847, DOI: 10.1186/1471-2148-13-31.Peer-Reviewed Original ResearchConceptsMtDNA haplotypesDifferent WolbachiaGenetic diversityHost haplotypesSequence diversityMultiple WolbachiaArthropod host reproductionPopulation genetic differentiationComplex evolutionary dynamicsMitochondrial DNA haplotypesAssociation of WolbachiaLow reproductive outputHost population geneticsHost genetic diversityTsetse fliesMulti-locus sequence typingMost WolbachiaHost genetic compositionGenetic differentiationWolbachia evolutionWolbachia associationsHost reproductionDNA haplotypesMtDNA groupsΑ-proteobacteria
2010
Population Genetic Structure of Aldabra Giant Tortoises
Balmer O, Ciofi C, Galbraith D, Swingland I, Zug G, Caccone A. Population Genetic Structure of Aldabra Giant Tortoises. Journal Of Heredity 2010, 102: 29-37. PMID: 20805288, DOI: 10.1093/jhered/esq096.Peer-Reviewed Original ResearchConceptsGenetic structurePopulation structureGiant tortoisesMitochondrial DNA control region sequencesPopulation genetic structureSignificant population structureControl region sequencesAldabra giant tortoisePrevious ecological studiesAllopatric divergenceNuclear lociPopulation subdivisionHabitat variationMtDNA sequencesMicrosatellite lociPopulation geneticsUnsuitable habitatGenetic variabilityAllelic variationRegion sequencesEcological factorsTerrestrial ecosystemsPopulation dynamicsAldabra AtollGeographical barriersPhylogeography and Population Structure of Glossina fuscipes fuscipes in Uganda: Implications for Control of Tsetse
Beadell JS, Hyseni C, Abila PP, Azabo R, Enyaru JC, Ouma JO, Mohammed YO, Okedi LM, Aksoy S, Caccone A. Phylogeography and Population Structure of Glossina fuscipes fuscipes in Uganda: Implications for Control of Tsetse. PLOS Neglected Tropical Diseases 2010, 4: e636. PMID: 20300518, PMCID: PMC2838784, DOI: 10.1371/journal.pntd.0000636.Peer-Reviewed Original ResearchConceptsGene flowPopulation structureLarge-scale genetic structureDivergent mitochondrial lineagesCurrent gene flowScale genetic structureBayesian assignment testsLittle gene flowHistorical colonization eventsZone of contactSouthern lineagesMitochondrial lineagesAssignment testsGenetic structureArea-wide controlMainland populationsColonization eventsMicrosatellite dataPopulation geneticsPhylogeographic analysisRiverine speciesIsland populationsAppropriate geographical scaleGenetic analysisMicrosatellite structure
2008
Colonization and diversification of Galpagos terrestrial fauna: a phylogenetic and biogeographical synthesis
Parent C, Caccone A, Petren K. Colonization and diversification of Galpagos terrestrial fauna: a phylogenetic and biogeographical synthesis. Philosophical Transactions Of The Royal Society B Biological Sciences 2008, 363: 3347-3361. PMID: 18782729, PMCID: PMC2607378, DOI: 10.1098/rstb.2008.0118.Peer-Reviewed Original ResearchConceptsTerrestrial faunaPhylogenetic studiesDivergence of populationsSimilar geological historyDistinct evolutionary historiesMolecular phylogenetic studiesRemote oceanic islandsRange of organismsStudy of diversificationHabitat specializationBiogeographical synthesisGeological historyLow vagilityDiverse habitatsEvolutionary historyGeological formationsOceanic islandsGroup of islandsGalápagos IslandsRemarkable settingUnique assemblageComparable climateEvolutionary processesFaunaIslands
2007
Cryptic biodiversity in a changing world
Beheregaray L, Caccone A. Cryptic biodiversity in a changing world. BMC Biology 2007, 6: 9. PMID: 18177504, PMCID: PMC2373901, DOI: 10.1186/jbiol60.Peer-Reviewed Original ResearchIndependent evolutionary origins of landlocked alewife populations and rapid parallel evolution of phenotypic traits
PALKOVACS E, DION K, POST D, CACCONE A. Independent evolutionary origins of landlocked alewife populations and rapid parallel evolution of phenotypic traits. Molecular Ecology 2007, 17: 582-597. PMID: 18179439, DOI: 10.1111/j.1365-294x.2007.03593.x.Peer-Reviewed Original ResearchConceptsLandlocked populationsAnadromous populationsAlewife populationSmaller adult body sizeRapid parallel evolutionLife history divergenceFreshwater ancestorsIndependent evolutionary originsDivergence time estimatesLife-history variantsGill raker spacingMicrosatellite mutation ratesMtDNA control regionAdult body sizeRate of evolutionSmall prey itemsAnadromous ancestorsForaging traitsPopulation divergenceAllele frequency dataDivergence timesEvolutionary ratesMicrosatellite dataAnadromous formEvolutionary origin
2006
An analysis of species boundaries and biogeographic patterns in a cryptic species complex: The rotifer—Brachionus plicatilis
Suatoni E, Vicario S, Rice S, Snell T, Caccone A. An analysis of species boundaries and biogeographic patterns in a cryptic species complex: The rotifer—Brachionus plicatilis. Molecular Phylogenetics And Evolution 2006, 41: 86-98. PMID: 16815046, DOI: 10.1016/j.ympev.2006.04.025.Peer-Reviewed Original ResearchConceptsCryptic species complexSpecies conceptSpecies boundariesCryptic complexesSpecies complexRotifer Brachionus plicatilisGenealogical species conceptMolecular sequence divergenceBiological species conceptEvidence of isolationMultiple species conceptsDifferent species conceptsLarge geographic scalesReproductive isolationMolecular phylogeneticsSpecies hypothesesBiogeographic patternsPhylogenetic dataSequence divergencePassive dispersalLarge vertebratesMarine invertebratesPhylogenetic studiesReproductive successCosmopolitan speciesMolecular phylogeny and historical biogeography of the land snail genus Solatopupa (Pulmonata) in the peri-Tyrrhenian area
Ketmaier V, Giusti F, Caccone A. Molecular phylogeny and historical biogeography of the land snail genus Solatopupa (Pulmonata) in the peri-Tyrrhenian area. Molecular Phylogenetics And Evolution 2006, 39: 439-451. PMID: 16442313, DOI: 10.1016/j.ympev.2005.12.008.Peer-Reviewed Original ResearchConceptsMolecular clock estimatesClock estimatesPeri-Tyrrhenian areaSardinia-Corsica microplateMain cladogenetic eventsNuclear genesVicariant processesCladogenetic eventsHistorical biogeographyMolecular phylogenyPhylogenetic resultsPhylogenetic relationshipsEvolutionary historyPhylogenetic hypothesisSister taxaInsular rangeGenetic relationshipsCalcareous substratesCorsica-Sardinia microplateMiddle–late PlioceneGenusSpeciesItalian peninsulaMiddle MioceneElba Island
2004
Variation in an intron sequence of the voltage‐gated sodium channel gene correlates with genetic differentiation between Anopheles gambiae s.s. molecular forms
Gentile G, Santolamazza F, Fanello C, Petrarca V, Caccone A, Della Torre A. Variation in an intron sequence of the voltage‐gated sodium channel gene correlates with genetic differentiation between Anopheles gambiae s.s. molecular forms. Insect Molecular Biology 2004, 13: 371-377. PMID: 15271209, DOI: 10.1111/j.0962-1075.2004.00494.x.Peer-Reviewed Original ResearchConceptsVoltage-gated sodium channel geneSodium channel geneGenetic differentiationGenetic variationChannel genesPossible selective sweepMajor haplotypesSingle mutational stepAnopheles gambiae MRDNA sitesGene flowSelective sweepsMutational stepsTaxonomic statusIntron sequencesGambiae MMolecular formsIntron ISingle localityIntronic regionsAnopheles gambiae s.Additional haplotypesGambiae s.HaplotypesGenesGiant tortoises are not so slow: Rapid diversification and biogeographic consensus in the Galápagos
Beheregaray L, Gibbs J, Havill N, Fritts T, Powell J, Caccone A. Giant tortoises are not so slow: Rapid diversification and biogeographic consensus in the Galápagos. Proceedings Of The National Academy Of Sciences Of The United States Of America 2004, 101: 6514-6519. PMID: 15084743, PMCID: PMC404076, DOI: 10.1073/pnas.0400393101.Peer-Reviewed Original ResearchConceptsGiant Galápagos tortoisesGalápagos tortoisesGreat natural laboratoryGenetic variationDivergent monophyletic cladesHistory of diversificationIsolated oceanic archipelagoPatterns of colonizationBiogeographic predictionsEvolutionary diversificationGene flowEndemic haplotypesExtant populationsLimited dispersalOceanic archipelagosBiogeographic patternsEvolutionary eventsBiological diversificationMonophyletic cladeMtDNA sequencesRapid diversificationGenetic interchangeRange expansionOlder islandsGiant tortoises
2003
Genetic structure of Mesoamerican populations of Big‐leaf mahogany (Swietenia macrophylla) inferred from microsatellite analysis
Novick R, Dick C, Lemes M, Navarro C, Caccone A, Bermingham E. Genetic structure of Mesoamerican populations of Big‐leaf mahogany (Swietenia macrophylla) inferred from microsatellite analysis. Molecular Ecology 2003, 12: 2885-2893. PMID: 14629370, DOI: 10.1046/j.1365-294x.2003.01951.x.Peer-Reviewed Original ResearchConceptsGenetic structurePhylogeographic structureStrong phylogeographic structureNeotropical tree speciesVariable microsatellite lociHigh-resolution markersBig-leaf mahoganyMahogany populationsGenetic differentiationCosta RicaBiogeographic historyNeotropical treeGenetic divergenceRegional biogeographyNative rangeNorthern populationsGenetic distanceGenetic diversityMicrosatellite lociAtlantic populationsPopulation structureAmerican treesMesoamerican populationsSwietenia macrophylla KingUnrooted dendrogramAre the native giant tortoises from the Seychelles really extinct? A genetic perspective based on mtDNA and microsatellite data
Palkovacs E, Marschner M, Ciofi C, Gerlach J, Caccone A. Are the native giant tortoises from the Seychelles really extinct? A genetic perspective based on mtDNA and microsatellite data. Molecular Ecology 2003, 12: 1403-1413. PMID: 12755870, DOI: 10.1046/j.1365-294x.2003.01834.x.Peer-Reviewed Original ResearchConceptsGiant tortoisesGenetic structuringGiant tortoise speciesMitochondrial DNA sequencesMitochondrial control regionWestern Indian OceanLevel of variationNuclear microsatellitesRediscovered speciesSeychelles archipelagoMicrosatellite dataReproductive isolationRecent morphological studiesTortoise speciesMicrosatellite lociControl regionSingle lineageMorphological charactersDNA sequencesCarapace morphologyCaptive conditionsTortoisesGenetic perspectiveSpeciesPotential survivalXantusiid “night” lizards: a puzzling phylogenetic problem revisited using likelihood-based Bayesian methods on mtDNA sequences
Vicario S, Caccone A, Gauthier J. Xantusiid “night” lizards: a puzzling phylogenetic problem revisited using likelihood-based Bayesian methods on mtDNA sequences. Molecular Phylogenetics And Evolution 2003, 26: 243-261. PMID: 12565035, DOI: 10.1016/s1055-7903(02)00313-5.Peer-Reviewed Original ResearchConceptsDivergence time estimatesXantusia riversianaCytochrome b geneMaximum parsimony analysisCalifornia Channel IslandsLikelihood-based Bayesian methodsIsland endemicsMitochondrial genesLizard evolutionAncestral stateScleroglossan lizardsRibosomal genesMtDNA sequencesPhylogenetic problemsCrown cladeAdditional cladesPhylogenetic analysisNeighbor-JoiningParsimony analysisB geneBoundary bolide impactRock crevicesCladeMaximum likelihoodXantusia
2002
PHYLOGEOGRAPHY AND HISTORY OF GIANT GALAPAGOS TORTOISES
Caccone A, Gentile G, Gibbs JP, Fritts T, Snell HL, Betts J, Powell JR. PHYLOGEOGRAPHY AND HISTORY OF GIANT GALAPAGOS TORTOISES. Evolution 2002, 56: 2052-2066. PMID: 12449492, DOI: 10.1111/j.0014-3820.2002.tb00131.x.Peer-Reviewed Original ResearchConceptsMultiple colonizationsMaternal lineagesMitochondrial DNA sequence dataClear genetic differentiationDNA sequence dataSanta Cruz IslandBiological treasureComplex phylogeographyGenetic differentiationExtant islandsPinzón IslandMolecular clockDeep nodesExtant taxaSequence dataVolcan WolfYounger islandsInsular environmentsHuman transportPhylogeographyTortoise populationsTaxaIsabela IslandDistinct populationsLineages
2001
MOLECULAR BIOGEOGRAPHY OF CAVE LIFE: A STUDY USING MITOCHONDRIAL DNA FROM BATHYSCIINE BEETLES
Caccone A, Sbordon V. MOLECULAR BIOGEOGRAPHY OF CAVE LIFE: A STUDY USING MITOCHONDRIAL DNA FROM BATHYSCIINE BEETLES. Evolution 2001, 55: 122-130. PMID: 11263733, DOI: 10.1111/j.0014-3820.2001.tb01278.x.Peer-Reviewed Original ResearchConceptsCave lifeCytochrome oxidase I regionLoss of traitsSimilar disjunct distributionsDistinct species assemblagesCave-dwelling beetlesCave adaptationMolecular biogeographyPhylogenetic relationshipsDisjunct distributionSister taxaSpecies assemblagesMitochondrial DNAEvolutionary acquisitionDNA sequencesFirst such estimatesCommon descentSpeciesBeetlesAssemblagesI regionSimilar morphologyGeological historyBiogeographyInsects
1997
Mitochondrial DNA Rates and Biogeography in European Newts (Genus Euproctus)
Caccone A, Milinkovitch M, Sbordoni V, Powell J. Mitochondrial DNA Rates and Biogeography in European Newts (Genus Euproctus). Systematic Biology 1997, 46: 126-144. PMID: 11975350, DOI: 10.1093/sysbio/46.1.126.Peer-Reviewed Original ResearchConceptsCytochrome b geneB geneDivergence timesMitochondrial DNA genesTime of divergenceMolecular clock hypothesisSardinia-Corsica microplateRate of evolutionMtDNA rateGene flowCladogenic eventsVicariant eventsMolecular divergenceTajima's testSequence divergenceRibosomal genesDNA genesPhylogenetic perspectiveVicariant distributionPhylogenetic studiesEuropean newtsRibosomal RNAClock hypothesisSequence dataRate heterogeneity