2019
Genetic Markers of Benzimidazole Resistance among Human Hookworms (Necator americanus) in Kintampo North Municipality, Ghana.
Orr AR, Quagraine JE, Suwondo P, George S, Harrison LM, Dornas FP, Evans B, Caccone A, Humphries D, Wilson MD, Cappello M. Genetic Markers of Benzimidazole Resistance among Human Hookworms (Necator americanus) in Kintampo North Municipality, Ghana. American Journal Of Tropical Medicine And Hygiene 2019, 100: 351-356. PMID: 30734697, PMCID: PMC6367626, DOI: 10.4269/ajtmh.18-0727.Peer-Reviewed Original ResearchConceptsMass drug administrationSoil-transmitted helminthsKintampo North MunicipalitySchool-aged childrenSingle nucleotide polymorphismsPolymerase chain reactionEffectiveness of MDAWild-type SNPsInfected study subjectsPeriodic mass drug administrationResistance-associated single nucleotide polymorphismsCross-sectional studyResistance-associated mutationsWorld Health OrganizationHookworm infectionDrug exposureHookworm eggsUnreported associationStudy subjectsDrug AdministrationPosttreatment samplesChemotherapeutic approachesGrowth delayHuman hookwormHealth Organization
2017
Genomic analyses of African Trypanozoon strains to assess evolutionary relationships and identify markers for strain identification
Richardson JB, Lee KY, Mireji P, Enyaru J, Sistrom M, Aksoy S, Zhao H, Caccone A. Genomic analyses of African Trypanozoon strains to assess evolutionary relationships and identify markers for strain identification. PLOS Neglected Tropical Diseases 2017, 11: e0005949. PMID: 28961238, PMCID: PMC5636163, DOI: 10.1371/journal.pntd.0005949.Peer-Reviewed Original ResearchConceptsAfrican trypanosomesHigh genetic similarityMaximum likelihood phylogenyStrain identificationGenomic resourcesGenetic structureEvolutionary relationshipsGenetic clustersPhylogenetic analysisGenomic analysisSingle nucleotide polymorphismsTaxonomic classificationGenetic similarityLarge comparative analysisGenetic markersHigh similarityGeographic originEvansi strainsSNPsNucleotide polymorphismsT. brucei bruceiPhylogenyTrypanosomesTrypanosomaTrypanozoon
2016
Asymmetric hybridization between non-native winter moth, Operophtera brumata (Lepidoptera: Geometridae), and native Bruce spanworm, Operophtera bruceata, in the Northeastern United States, assessed with novel microsatellites and SNPs
Havill N, Elkinton J, Andersen J, Hagen S, Broadley H, Boettner G, Caccone A. Asymmetric hybridization between non-native winter moth, Operophtera brumata (Lepidoptera: Geometridae), and native Bruce spanworm, Operophtera bruceata, in the Northeastern United States, assessed with novel microsatellites and SNPs. Bulletin Of Entomological Research 2016, 107: 241-250. PMID: 27876095, DOI: 10.1017/s0007485316000857.Peer-Reviewed Original ResearchConceptsSingle nucleotide polymorphismsMicrosatellite lociBruce spanwormAsymmetric hybridizationWinter mothSpecies-diagnostic single nucleotide polymorphismsOperophtera brumataVariable microsatellite lociNon-native pestsTypes of markersBacterial symbiontsGenetic incompatibilitiesGenomic approachesLaboratory crossesNative speciesAsymmetrical hybridizationPopulation geneticsPutative hybridsHybrid backcrossesNovel microsatellitesForest treesOperophtera bruceataO. bruceataReciprocal crossesGenetic markersEvidence of temporal stability in allelic and mitochondrial haplotype diversity in populations of Glossina fuscipes fuscipes (Diptera: Glossinidae) in northern Uganda
Opiro R, Saarman NP, Echodu R, Opiyo EA, Dion K, Halyard A, Aksoy S, Caccone A. Evidence of temporal stability in allelic and mitochondrial haplotype diversity in populations of Glossina fuscipes fuscipes (Diptera: Glossinidae) in northern Uganda. Parasites & Vectors 2016, 9: 258. PMID: 27141947, PMCID: PMC4855780, DOI: 10.1186/s13071-016-1522-5.Peer-Reviewed Original Research
2011
Lineage Identification and Genealogical Relationships Among Captive Galápagos Tortoises
Benavides E, Russello M, Boyer D, Wiese R, Kajdacsi B, Marquez L, Garrick R, Caccone A. Lineage Identification and Genealogical Relationships Among Captive Galápagos Tortoises. Zoo Biology 2011, 31: 107-120. PMID: 21674601, DOI: 10.1002/zoo.20397.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, WildAnimals, ZooGenetic MarkersGenomicsHaplotypesMicrosatellite RepeatsTurtlesConceptsGenealogical relationshipsGalápagos tortoisesEx situ conservation programsMicrosatellite genotypic dataSan Diego ZooGalápagos giant tortoisesWild-born individualsSitu conservation programsLevels of relatednessDetailed management recommendationsSanta Cruz IslandEvolutionary lineagesAssignment testsGenetic toolsSpecies designationRelated foundersGiant tortoisesGenotypic dataUnknown ancestryHaplotypic dataPedigree relationshipsDifferent speciesLineage identificationIsabela IslandConservation programs
2005
A cryptic taxon of Galpagos tortoise in conservation peril
Russello M, Glaberman S, Gibbs J, Marquez C, Powell J, Caccone A. A cryptic taxon of Galpagos tortoise in conservation peril. Biology Letters 2005, 1: 287-290. PMID: 17148189, PMCID: PMC1617146, DOI: 10.1098/rsbl.2005.0317.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsDNAExtinction, BiologicalGenetic MarkersGenetic VariationGenetics, PopulationPhylogenySpecies SpecificityTurtlesConceptsBiological diversityFormal taxonomic designationGenetic divergenceGalápagos tortoisesAccurate taxonomyDistinct lineagesTaxonomic investigationGenetic divisionTaxonomic designationsSingle taxonGiant tortoisesBad taxonomyEvolutionary heritageNew taxonTaxaAccessible islandsTortoisesHuman intellectual historyDiversityConservationSanta CruzTaxonomyLineagesGalápagosOrganisms