2020
Improved reference genome of the arboviral vector Aedes albopictus
Palatini U, Masri RA, Cosme LV, Koren S, Thibaud-Nissen F, Biedler JK, Krsticevic F, Johnston JS, Halbach R, Crawford JE, Antoshechkin I, Failloux AB, Pischedda E, Marconcini M, Ghurye J, Rhie A, Sharma A, Karagodin DA, Jenrette J, Gamez S, Miesen P, Masterson P, Caccone A, Sharakhova MV, Tu Z, Papathanos PA, Van Rij RP, Akbari OS, Powell J, Phillippy AM, Bonizzoni M. Improved reference genome of the arboviral vector Aedes albopictus. Genome Biology 2020, 21: 215. PMID: 32847630, PMCID: PMC7448346, DOI: 10.1186/s13059-020-02141-w.Peer-Reviewed Original ResearchConceptsArboviral vector Aedes albopictusSex-determining locusFirst physical mapAsian tiger mosquito Aedes albopictusTiger mosquito Aedes albopictusMosquito Aedes albopictusAedes albopictusPiRNA clustersDiverse AeGenome assemblyInnovative control measuresReference genomeAccurate DNA sequencesNovel microRNAsImmunity genesPhysical mapDNA sequencesGenetic manipulationViral insertionVector Aedes albopictusExpression dataGenomeAlbopictus populationsSequencing methodsAdaptation potential
2016
De Novo Genome Assembly Shows Genome Wide Similarity between Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense
Sistrom M, Evans B, Benoit J, Balmer O, Aksoy S, Caccone A. De Novo Genome Assembly Shows Genome Wide Similarity between Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense. PLOS ONE 2016, 11: e0147660. PMID: 26910229, PMCID: PMC4766357, DOI: 10.1371/journal.pone.0147660.Peer-Reviewed Original ResearchConceptsGenome assemblyGenetic recombinationT. bruceiPentatricopeptide repeat-containing proteinGenome-wide similarityDe novo genome assemblyHybrid de novo assemblyComparative genomic analysisRepeat-containing proteinVariant surface glycoprotein (VSG) coatComplete genome assemblyDe novo assemblyNovo genome assemblyGenomic differentiationSignificant epidemiological consequencesWhole-genome sequencingGene familyPutative genesEukaryotic pathogensNovo assemblySerum resistance associated geneHuman infective strainsGenomic analysisSingle geneAlcohol oxidoreductase