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Yale Psychiatry Grand Rounds: January 13, 2023

January 13, 2023
  • 00:00One of the kindest and nicest
  • 00:02introductions I've ever received.
  • 00:04And likewise, I've very much enjoyed
  • 00:07continuing my Yale connections,
  • 00:09especially through as many Dave,
  • 00:11Mark many other folks who are doing
  • 00:13just such amazing addiction work at
  • 00:15the West Haven VA, but also at Yale.
  • 00:18I'm going to share my screen.
  • 00:25And then start in slideshow mode.
  • 00:27Please someone stop me if you're
  • 00:29not seeing this correctly,
  • 00:30but I'm just going to proceed.
  • 00:31I do have to say that my Med school
  • 00:33self would have been super tickled
  • 00:35to know that I would be giving this
  • 00:38presentation a number of years later,
  • 00:40so it does make me laugh.
  • 00:41I was scrolling through the list of
  • 00:43attendees and it was smiling from quite
  • 00:44a number of people that I recognized.
  • 00:46So this really brings me a lot of
  • 00:48joy to be able to have the chance
  • 00:50to talk to you guys here today.
  • 00:52So as Doctor Petrakis mentioned,
  • 00:54my work really focuses on improving
  • 00:56care for patients with opioid and
  • 00:57other substance use disorders,
  • 00:58with a specific focus on telehealth.
  • 01:01And today,
  • 01:01I'm really excited to be able to
  • 01:03talk about optimizing telehealth
  • 01:04for addiction care,
  • 01:05both from lessons that we
  • 01:07learned before COVID,
  • 01:07during COVID and hopefully informing
  • 01:09what care in the future should look like.
  • 01:13These are my disclosures.
  • 01:14In addition to my grant funding,
  • 01:16I consulted for the NC QA with
  • 01:18funding from ALCHEMIES and for
  • 01:20the provider clinical support
  • 01:22system with funding from Sansa.
  • 01:26So most folks I think here have
  • 01:28seen this figure, but I still think
  • 01:30it's an important one to remember.
  • 01:32And the emphasis that I would put is
  • 01:34that long before the pandemic started,
  • 01:36the US was already battling
  • 01:38the overdose epidemic.
  • 01:39It's important to emphasize though
  • 01:40how things have continued to evolve
  • 01:42away from prescription opioids,
  • 01:43which is what started at least
  • 01:46this particular epidemic,
  • 01:47to illicit opioids including heroin and
  • 01:49really mostly in the last five years or so,
  • 01:52fentanyl that have tainted much of the
  • 01:54drug supply in this country including.
  • 01:56But not limited to opioids.
  • 01:58And that brings us to what some of
  • 02:00us call the 4th wave of the overdose
  • 02:02epidemic in the last few years,
  • 02:04which encompasses substances like
  • 02:05stimulants and really people
  • 02:07who are using and overdosing on
  • 02:10multiple or Poly substances.
  • 02:12Regardless,
  • 02:12as the trends change and they
  • 02:14will continue to change,
  • 02:15one thing remains the same and
  • 02:17that's the critical importance of
  • 02:19treating addiction and these days,
  • 02:20the importance of treating our
  • 02:22typical patient who's struggling with
  • 02:23multiple substance use disorders
  • 02:25and other mental health disorders.
  • 02:28Unfortunately, estimates since the start
  • 02:30of the pandemic almost three years ago
  • 02:33now suggest that overdose rates and
  • 02:35substance use continues to increase.
  • 02:37And it's important, I think,
  • 02:38to remember that the pandemic has
  • 02:40not affected our population equally.
  • 02:42Many of us, myself included,
  • 02:44have been largely spared.
  • 02:45You know, transitioning.
  • 02:46My work to zoom was not a big challenge.
  • 02:50But for many of our patients though,
  • 02:52due to many increased stressors
  • 02:53during the last three years,
  • 02:55they're struggling even more.
  • 02:56And there are signs that many people
  • 02:58have turned even more to risky
  • 03:00use of alcohol and drugs to cope,
  • 03:02which is compounded in particular by
  • 03:03disruptions in the healthcare services,
  • 03:05especially early on in the pandemic,
  • 03:07some of which have not rebounded,
  • 03:09which I hope to show.
  • 03:12However, given the many negative
  • 03:14consequences of substance use disorders,
  • 03:16especially untreated,
  • 03:17the important thing for all of us
  • 03:19to emphasize is that we actually
  • 03:21have highly effective treatments.
  • 03:22This includes the three effective medication
  • 03:25treatments for opioid use disorders,
  • 03:27specifically methadone, buprenorphine,
  • 03:28and extended release naltrexone.
  • 03:31We have decades of research how much of
  • 03:33it originating at Yale to show that these
  • 03:36medications not only reduce opioid use,
  • 03:38improve functioning or cost
  • 03:40effective and are associated with
  • 03:42reductions in mortality rates.
  • 03:44And as a psychiatrist,
  • 03:44there's actually not a whole lot of
  • 03:46treatments I deliver where there's
  • 03:48been consistent data to support that.
  • 03:49It actually reduces rates of
  • 03:52death for our patient population.
  • 03:54In addition, of course,
  • 03:56we have numerous other effective
  • 03:58medication and psychotherapy treatments
  • 03:59for other substance use disorders,
  • 04:02including motivational enhancement,
  • 04:03cognitive behavioral therapy,
  • 04:05contingency management for range
  • 04:06of substance use disorders that
  • 04:08equally have decades of research
  • 04:10supporting their effectiveness.
  • 04:14However, although we've had these
  • 04:16effective treatments for some for
  • 04:18a very long time, we know that
  • 04:19some of them can really save lives.
  • 04:21Only a tiny fraction of patients in the
  • 04:24US receive these effective treatments.
  • 04:26Estimates show that about 1/3 of
  • 04:28patients with opioid use disorder receive
  • 04:30the effect of medication treatments.
  • 04:32The rates are slightly higher in the VA,
  • 04:34but not by too much.
  • 04:35But treatment rates are actually
  • 04:37much lower for many of the other
  • 04:39substance use disorders,
  • 04:40including those that are much
  • 04:41more prevalent than opioid use.
  • 04:43This order, for example,
  • 04:45alcohol treatment rates show that
  • 04:47treatment for those diseases
  • 04:49hover close to 10%.
  • 04:50Can you imagine if only 10% of this
  • 04:53country is getting their diabetes treated,
  • 04:55their cancer treated,
  • 04:56or even their depression treated?
  • 04:59But of course, there's the further
  • 05:00challenge in addiction care.
  • 05:02And it's not just about helping
  • 05:03people get started in treatment.
  • 05:05We also have to help people stay
  • 05:08in their addiction care.
  • 05:09For example,
  • 05:10we know that retention or how long
  • 05:12people stay on their medications
  • 05:14for opioid use disorder hovers
  • 05:15at about 50% at three months,
  • 05:17according to some estimates.
  • 05:19And the corollary to that?
  • 05:20Is that we know overdose rates and
  • 05:23other negative outcomes really
  • 05:24jump after people stop treatments
  • 05:26of these medications,
  • 05:27which these medications only
  • 05:29work when people are taking them.
  • 05:31That's a little bit different for
  • 05:32other psychotherapy treatments,
  • 05:33but this is still an important thing,
  • 05:34I think, to emphasize.
  • 05:38And so the key question I think
  • 05:40for all of us to be thinking about
  • 05:42is why are treatment rates for
  • 05:44these effective therapies so low?
  • 05:46And for me it's helpful to think
  • 05:49about it under a rubric or conceptual
  • 05:51model of three main barriers.
  • 05:53The first related to stigma,
  • 05:56second related to the underlying
  • 05:58illness and symptoms of addiction,
  • 05:59and finally related to limited access,
  • 06:02accessibility and other
  • 06:03system related barriers.
  • 06:05I would say stigma remains
  • 06:07a very large barrier.
  • 06:08At the societal level,
  • 06:09at the healthcare system level,
  • 06:11at the Community level,
  • 06:12but also stigma affecting our patients.
  • 06:15One of the things that we still hear
  • 06:17the most is that it took many of our
  • 06:19patients years to overcome the stigma
  • 06:20in order to feel that they had an
  • 06:22illness that could actually be treated.
  • 06:24But this point also,
  • 06:25I think highlights a specific or
  • 06:27unique challenge with substance
  • 06:28use disorders and that is that
  • 06:30the disease itself makes it hard
  • 06:32for people to seek treatment.
  • 06:33It's the only medical illness
  • 06:36whereby definition,
  • 06:37the person has a hard time cutting
  • 06:39down and engaging in care despite the
  • 06:42negative consequences that they feel.
  • 06:44So by definition,
  • 06:45addiction makes it really hard for a
  • 06:47person who's already struggling to seek care.
  • 06:50And I think for me what that
  • 06:51means is we actually have to make
  • 06:54addiction care much more accessible,
  • 06:55much more appealing than any other illnesses.
  • 06:58And I think at this point we
  • 07:00know that that's not the case.
  • 07:02According to the National
  • 07:03Survey of Drug Use and Health,
  • 07:04or Nista,
  • 07:05an annual survey population
  • 07:06based survey in the US,
  • 07:08these are all reasons that
  • 07:10contribute to why patients themselves
  • 07:12say are barriers that they are
  • 07:14unable to engage in treatment.
  • 07:16And so for the rest of today,
  • 07:18I'll actually spend this time
  • 07:19focusing on the system level changes
  • 07:21that I think are needed to try to
  • 07:23address some of these disparities.
  • 07:27So one challenge when it comes to
  • 07:29our healthcare system and treatment
  • 07:30access is the inadequate number of
  • 07:32trained clinicians across the US,
  • 07:34but just not just the total number
  • 07:36but really how they're distributed.
  • 07:38So this map shows the density of
  • 07:41addiction psychiatrists across
  • 07:42counties in the US and as you can see,
  • 07:44most of it is Gray,
  • 07:46which means that most of the addiction
  • 07:48psychiatrists in this country,
  • 07:49in this country are concentrated in
  • 07:52densely populated or academic centers
  • 07:54like where New Haven and Ann Arbor.
  • 07:57But the vast majority of counties in
  • 07:58the US do not have a single addiction
  • 08:01psychiatrist and there are obviously
  • 08:03many other addiction clinicians,
  • 08:04including other types of
  • 08:06addiction physicians.
  • 08:07But it's clear that not only access
  • 08:09but accessibility to evidence
  • 08:11based addiction care is sorely
  • 08:12lacking for much of the country.
  • 08:15And it's a major challenge in
  • 08:17particular to get treatment to
  • 08:18where our patients actually are.
  • 08:20I would like to also emphasize
  • 08:22though that the limited access for
  • 08:24addiction care is really exacerbated
  • 08:26by the fact that distance has an
  • 08:28outsized effect for our patients.
  • 08:30Prior studies have shown that longer
  • 08:32distance to treatment is a major
  • 08:34factor for patients discontinuing
  • 08:35care and the impact of distance
  • 08:37to treatment is really magnified
  • 08:39in addiction treatment where we're
  • 08:40oftentimes asking our patients
  • 08:42to come on a regular basis,
  • 08:44even as frequently as weekly and
  • 08:46sometimes for a long period of time,
  • 08:48so months or years,
  • 08:49often when it comes to our medication.
  • 08:51Statements.
  • 08:51So when many of our patients are having
  • 08:54to take multiple buses and shuttles
  • 08:55to make it to a single appointment,
  • 08:58which would be challenging for
  • 08:59any of us to engage in care,
  • 09:01let alone when combined with all
  • 09:03the other barriers that I mentioned,
  • 09:04specifically stigma and the symptoms
  • 09:06that they face as part of their addiction.
  • 09:10And so, given these particular
  • 09:12barriers that I've mentioned,
  • 09:14I think there's a clear need to
  • 09:16make treatment more accessible.
  • 09:17And telehealth has long
  • 09:18been a promising tool,
  • 09:20in particular within psychiatry,
  • 09:22well before COVID.
  • 09:23But the question still remains,
  • 09:24can telehealth actually improve
  • 09:26substance use disorder care?
  • 09:28As Doctor Petrakis mentioned,
  • 09:29there's been a small group of us,
  • 09:31including myself, Doctor Moore,
  • 09:33and others who've been working
  • 09:34in the space well before COVID.
  • 09:36For me, it was mostly because I was
  • 09:38lucky enough to have worked with.
  • 09:40Uh, an attendee who had been using
  • 09:42video to deliver buprenorphine
  • 09:44care in the VA before COVID.
  • 09:46And but that's just a sign that we
  • 09:47have long known that our patients
  • 09:49with addiction struggle with
  • 09:51getting access and staying in care.
  • 09:52COVID just exacerbated that,
  • 09:54but it was really never a new problem.
  • 09:58So although there have been dozens of
  • 10:00studies examining the effectiveness of
  • 10:02telehealth interventions for mental health,
  • 10:04and telehealth really had its birth,
  • 10:06I would say, in psychiatric care,
  • 10:08mental health.
  • 10:09And all of these studies by and
  • 10:11large have shown that telehealth
  • 10:13specifically video delivery care,
  • 10:15which is where most of the
  • 10:17studies are focused on.
  • 10:18That's not to say that other
  • 10:20interventions are not effective,
  • 10:21but that's where the historically
  • 10:22the research is focused is no worse
  • 10:25or non inferior with outcomes
  • 10:27compared to in person care.
  • 10:29However,
  • 10:29we've noted that there have been
  • 10:31far fewer studies of telehealth
  • 10:33studies in patients with substance
  • 10:34use disorders and this motivated a
  • 10:37systematic review that I conducted
  • 10:38with colleagues at the University of
  • 10:40California that was published in 2019.
  • 10:43This review actually went on to
  • 10:44inform policy makers for the medical
  • 10:46so the Medicaid program in the
  • 10:48state of California as they were
  • 10:50making decisions on what types of
  • 10:52telehealth for substance use disorders
  • 10:54or services to cover however,
  • 10:56the overall goal of this study.
  • 10:59Just to examine the evidence on
  • 11:01telemedicine deliver treatment interventions.
  • 11:02So not necessarily other augmenting
  • 11:04kind of interventions,
  • 11:06but really treatment specifically for
  • 11:08patients with substance use disorders.
  • 11:10At that point,
  • 11:11we took a very broad inclusion
  • 11:13criteria because we already knew
  • 11:14about the limited number of
  • 11:16studies that were available.
  • 11:17We included studies that examined a broad
  • 11:19range of outcomes including effectiveness,
  • 11:22but also patient level outcomes
  • 11:24like acceptability, satisfaction,
  • 11:25things that were also from
  • 11:28single arm pilot studies.
  • 11:30And we also included studies that were
  • 11:32both retrospective as well as prospective.
  • 11:34Very few of these studies,
  • 11:35by the way were actually RCT's.
  • 11:37In total at that time,
  • 11:39we only found 13 studies meeting
  • 11:41our broad inclusion criteria,
  • 11:423 focused on tobacco treatment,
  • 11:445 on alcohol and five on
  • 11:46opioid use disorders.
  • 11:47And to briefly summarize,
  • 11:48we found across these studies some indicators
  • 11:51of comparable therapeutic alliance,
  • 11:54particularly with psychotherapy
  • 11:55studies and retention and care,
  • 11:58though there were no fully powered studies.
  • 12:00No prospective studies
  • 12:02actually for any medication,
  • 12:04treatments for substance use
  • 12:05disorders and the overall quality
  • 12:07of methods were somewhat limited.
  • 12:11And so from this review,
  • 12:14we noted that there were a number of areas
  • 12:16that really deserved a further research,
  • 12:19actually quite a number of areas
  • 12:20and we kind of summarized them
  • 12:22into into three large groups.
  • 12:24So most of the studies that we
  • 12:26found were again kind of comparing
  • 12:28video telehealth within person care.
  • 12:30And the question is not only are we
  • 12:33interested in whether or not video
  • 12:34telehealth is no worse than in person care,
  • 12:37but can telehealth actually
  • 12:39extend or increase treatment.
  • 12:41And for different sectors of
  • 12:42the populations and for which
  • 12:44patients also effectiveness of
  • 12:45different models of telehealth.
  • 12:47I think as you'll hear today
  • 12:48from Doctor Moore and myself,
  • 12:50you know the telehealth
  • 12:51that we think of right now,
  • 12:52which is really us talking over zoom,
  • 12:54that's really what I hope to be the tip
  • 12:56of the iceberg and hopefully it gives
  • 12:58room for lots of innovations about
  • 13:00delivering care in new ways to our patients.
  • 13:02And lastly,
  • 13:03also the importance of examining patient
  • 13:05and clinician experiences and preferences,
  • 13:07especially when it comes to telehealth
  • 13:09implementation in the real world.
  • 13:13And so I mentioned that
  • 13:15we included 13 studies.
  • 13:17I also want to highlight two
  • 13:19additional studies that are really
  • 13:21fast focused on telehealth in real
  • 13:23world settings and healthcare
  • 13:25systems prior to the pandemic.
  • 13:26And the first study is really a
  • 13:28study published by Hayden Huskamp
  • 13:30and colleagues at Harvard.
  • 13:31They examined trends in the use
  • 13:33of telehealth for both mental
  • 13:35health and substance use disorder
  • 13:37treatment including within patients
  • 13:39or using patients who were in
  • 13:42a private insurance systems.
  • 13:44So this did not include patients
  • 13:45who were on Medicaid or Medicare,
  • 13:46but this was a national sample of
  • 13:48patients with private insurance.
  • 13:50And they found that use of telehealth
  • 13:52for both mental health and substance
  • 13:55use disorders increased quite
  • 13:56substantially from 2010 to 2017.
  • 13:58But the use of substance use disorder care,
  • 14:00as you'll see from this figure,
  • 14:02remained much lower than other
  • 14:04mental healthcare pre COVID.
  • 14:06And so there are likely things
  • 14:08about addiction care.
  • 14:09Either the historical systems
  • 14:10that we're used to that have been
  • 14:13used to deliver addiction care,
  • 14:14the elements of treatment,
  • 14:15for example,
  • 14:16including things like urine
  • 14:17toxicology screens,
  • 14:18or even the treatments themselves,
  • 14:20including group therapy and things like that,
  • 14:22that might have made telehealth
  • 14:24adoption lower even before the pandemic.
  • 14:29So the other study I wanted to
  • 14:31highlight is a study by our team.
  • 14:33We examined telehealth specifically
  • 14:34for opioid use disorder treatment of
  • 14:37buprenorphine pre COVID and the BHA.
  • 14:40In that study, we included veterans who
  • 14:42received any buprenorphine treatment
  • 14:44from fiscal year 2012 through 2019 and
  • 14:46similar we saw overall increases until
  • 14:49health use for buprenorphine treatment.
  • 14:51So that by 2019 about 8% of patients
  • 14:54receiving any buprenorphine for OUD
  • 14:56have received some form of telemedicine.
  • 14:58At least once and in this paper we detailed
  • 15:01also characteristics of patients who
  • 15:03received telehealth versus in person care.
  • 15:05But the thing I want to emphasize most of
  • 15:08all is that in the study pre COVID teller,
  • 15:10buprenorphine looked quite different
  • 15:12than it does now prior to COVID and
  • 15:15specifically prior to the support
  • 15:16Act of 2018 telling buprenorphine
  • 15:18was mostly limited to telehealth
  • 15:20from clinicians in a large clinic,
  • 15:23for example, our large healthcare
  • 15:24systems seeing patients via video who
  • 15:26are presenting in a rural clinic.
  • 15:28And not at home,
  • 15:30which is obviously what a large proportion
  • 15:32of telehealth looks like these days.
  • 15:34This is what we were doing in Ann
  • 15:36Arbor starting about five years ago.
  • 15:38We were early adopters because
  • 15:39well before the pandemic,
  • 15:40we realized that although
  • 15:42our large PA system,
  • 15:43which is located in Ann Arbor, MI,
  • 15:45many of our patients were needing care,
  • 15:48especially those who are presenting in
  • 15:49the HVAC box or the community clinics.
  • 15:51For example,
  • 15:52the one in Flint, MI,
  • 15:53really had no addiction providers and
  • 15:55that's kind of what had motivated us to
  • 15:57start seeing patients via telehealth.
  • 15:59Um, back then.
  • 16:00But again,
  • 16:00they were presenting in a
  • 16:03in a community clinic.
  • 16:05But of course came COVID-19 and
  • 16:08that has radically changed the
  • 16:10way Healthcare is delivered.
  • 16:11I think all of us in the healthcare system
  • 16:14have felt this in numerous different ways,
  • 16:16but it's important to think
  • 16:18about exactly what the impacts
  • 16:19are of specific policy changes,
  • 16:21both at the federal and the state level
  • 16:23and the extent of these policy changes.
  • 16:26I summarized the main changes
  • 16:28here in this slide and I just
  • 16:30wanted to highlight a few.
  • 16:32Many of us are specifically familiar
  • 16:34with the Ryan Hate Act exemption,
  • 16:36a federal law which in the current public
  • 16:40health emergency declared as part of COVID.
  • 16:43It's allowed us to prescribe if you've been
  • 16:45morphine and other controlled medications
  • 16:47without an initial in person visit.
  • 16:49But I want to emphasize that it's also not
  • 16:51just that and in fact potentially that
  • 16:54is really one of the smaller impacts.
  • 16:56But a combination of many different
  • 16:58policy changes at the federal and
  • 17:00state levels that have allowed for
  • 17:02substantial increases in telehealth
  • 17:03use that I'm going to be showing.
  • 17:05And in particular,
  • 17:06I would say,
  • 17:07Sam says allowance of phone visits
  • 17:08for the first time for if you've been
  • 17:11orphine treatment was a big impact.
  • 17:13Also major changes in reimbursement.
  • 17:16So prior to COVID,
  • 17:17CMS or the Center for Medicaid and Medicare,
  • 17:20we're really only allowing
  • 17:22telehealth services to be reimbursed
  • 17:24for rural patients with a very
  • 17:26strict definition of morality.
  • 17:27You were presenting in rural clinics,
  • 17:29so all of these changes were needed to
  • 17:32really decrease barriers to telehealth,
  • 17:34and all of these changes
  • 17:36are currently under debate.
  • 17:39And so given all the policy changes
  • 17:41since the start of the pandemic,
  • 17:43I think it's really important to examine
  • 17:45the impacts on treatment longer term.
  • 17:48And a paper from our team that
  • 17:49was recently published in the
  • 17:51American Journal of Psychiatry,
  • 17:52we examined the impact of the
  • 17:54COVID-19 related changes at the
  • 17:55federal level occurring in March of
  • 17:572020 on buprenorphine treatment in
  • 17:59the entire population of veterans
  • 18:01with opioid use disorder in the VHA,
  • 18:03which is also the largest single
  • 18:05addiction provider in this country.
  • 18:08In this figure,
  • 18:09what you'll see is that the blue
  • 18:10line represents in person visits for
  • 18:13buprenorphine treatment and starting
  • 18:14very quickly after March of 2020,
  • 18:16you see a major shift away from in
  • 18:18person visits towards phone visits
  • 18:20which is represented by the Orange
  • 18:22Line and then video visits the green
  • 18:25line with phone continuing to exceed
  • 18:27video visits by February of 2021.
  • 18:29Overall,
  • 18:30we found that over a very short
  • 18:32period of time,
  • 18:33use of telehealth increase from about 10%
  • 18:36of patients to over 80% for buprenorphine.
  • 18:38Treatment with the majority of
  • 18:40those visits being telephone visits.
  • 18:42And at the same time we found that the
  • 18:44monthly number of patients receiving
  • 18:46buprenorphine actually increased slightly,
  • 18:47but mostly due to patients staying
  • 18:49on treatment longer and not due
  • 18:52to more patients initiating here.
  • 18:54So although COVID has greatly disrupted
  • 18:56care across our healthcare system,
  • 18:58I think what these results suggest is
  • 19:00that telehealth has actually helped
  • 19:01to sustain a crucial treatment for
  • 19:03veterans with opioid use disorder,
  • 19:04which is a particularly vulnerable
  • 19:06population who we could have hypothesized
  • 19:08might have actually been a group
  • 19:09to have seen large drops in care.
  • 19:11A big concern for many of us now
  • 19:13is that as care has begins to shift
  • 19:15or many ways have already shifted
  • 19:17back into person due to clinic
  • 19:19policies and changing COVID-19,
  • 19:21could this actually adversely affect?
  • 19:23Over our patients,
  • 19:24many of whom have only known
  • 19:26treatment through telehealth.
  • 19:29And so that prior study looked at examining
  • 19:32shifts and trends throughout the period
  • 19:35one year before COVID to one year after.
  • 19:38But I think the key question that
  • 19:39many of us also are curious about
  • 19:41is how does tell healthcare actually
  • 19:43compare directly with in person
  • 19:45visits and also phone with video and
  • 19:47examining the trends across COVID,
  • 19:49like what I showed before doesn't actually
  • 19:51answer that question because it's also
  • 19:53confounded by the overall effects of COVID,
  • 19:55which obviously affected our
  • 19:56healthcare delivery and patient use,
  • 19:58so in another study.
  • 20:00That we recently published in
  • 20:01our team led by Doctor Frost,
  • 20:03Madeline Frost at University of Washington.
  • 20:06We compare both the characteristics of
  • 20:08patients who use different treatment
  • 20:09modalities and also looked at the
  • 20:11association between the treatment modality
  • 20:13used and important outcome of retention
  • 20:15on buprenorphine treatment across video,
  • 20:18phone and in person visits.
  • 20:20In a population of veterans with
  • 20:22opioid use disorder in the one
  • 20:25year post COVID and in that study,
  • 20:27we found that in this period 88% of
  • 20:30veterans received buprenorphine for OUD
  • 20:32receive some form of telehealth visits.
  • 20:34However,
  • 20:35there were still important differences
  • 20:37in who received video versus phone versus
  • 20:39in person visits and characteristics
  • 20:41associated with being less likely to
  • 20:43receive telehealth included being younger,
  • 20:45male, black,
  • 20:46Hispanic,
  • 20:47and having comorbid other STD's.
  • 20:50And among patients who received
  • 20:52any telehealth,
  • 20:53those who were much more likely
  • 20:55to receive phone visits were
  • 20:56older black or homeless patients.
  • 20:58And lastly,
  • 20:59and I would say very importantly,
  • 21:01we found that patients who received
  • 21:02any telehealth in this time period
  • 21:04compared to those who received
  • 21:06only in person visits were actually
  • 21:08more likely to be retained at 90
  • 21:10days compared to patients who
  • 21:12only received in person visits.
  • 21:13And this is a very important
  • 21:15outcome for a lot of us who study
  • 21:17opioid use disorder treatment,
  • 21:18really retention on buprenorphine is what we.
  • 21:21Focus on as being a key outcome measure,
  • 21:23which has been associated with
  • 21:25numerous other benefits for patients.
  • 21:29And so similar findings I want to emphasize
  • 21:32has been seen in non veteran populations.
  • 21:35In a recent study by Chris
  • 21:36Jones at the CDC and colleagues,
  • 21:38they examined Medicare fee for
  • 21:40service patients in the US.
  • 21:41They compared a cohort of patients
  • 21:43with opioid use disorder immediately
  • 21:45prior to the pandemic and another
  • 21:47cohort after the start of the pandemic.
  • 21:49And they found that telehealth
  • 21:51for any opioid use disorder care,
  • 21:53which in their study they were not
  • 21:54able to associate the telehealth
  • 21:56visit directly to the medication treatment.
  • 21:57But really.
  • 21:58Encompassing any OU D care,
  • 22:00they found that telehealth visits
  • 22:02increased from 0.6% to 19.6%,
  • 22:04which is a substantial increase,
  • 22:07I would say,
  • 22:07in a very short period of time
  • 22:09where in healthcare not a whole
  • 22:10lot of things change that quickly,
  • 22:12but as of course lower than the
  • 22:14increase that we saw in the VA.
  • 22:16They also found that receipt of any
  • 22:19telehealth for OUD care was associated
  • 22:21with increased retention on medications
  • 22:24and also they found that receipt of
  • 22:26any telehealth was associated with a
  • 22:29decreased risk for overdose related visits.
  • 22:31So patients were less likely to
  • 22:33be seen in the emergency room,
  • 22:34hospitalized,
  • 22:35inpatient related to overdose,
  • 22:38those who had received any telehealth
  • 22:39compared to those who had not.
  • 22:41Again this is these are not randomized
  • 22:43controlled trials but this is the
  • 22:44best that these are the best methods.
  • 22:46That we have at hand,
  • 22:47especially so shortly after the
  • 22:49start of COVID, all of the data,
  • 22:52this data is suggesting that
  • 22:53telehealth could be associated with
  • 22:55improved outcomes for patients
  • 22:56with opioid use disorder.
  • 23:00And so in summary, I think what we have
  • 23:02learned from these early studies and you
  • 23:04know for most folks in the audience,
  • 23:06you know that research typically
  • 23:07takes a long time. So COVID has been
  • 23:09a real challenge for some of us.
  • 23:11What we're starting to get a sense
  • 23:13is that telehealth for opioid use
  • 23:15disorder treatment largely likely
  • 23:16helps sustain a critical treatment
  • 23:18for a very vulnerable and complex
  • 23:20population during a time when much of
  • 23:22healthcare utilization was decreasing.
  • 23:24Other studies have shown that use of
  • 23:26other medical care were decreasing
  • 23:27actually during the same period
  • 23:29of time these early studies.
  • 23:31Also indicate that telehealth was associated
  • 23:33with potentially improved outcomes,
  • 23:34including improved retention and care,
  • 23:37and potentially even lower overdose rates,
  • 23:39though future studies are really
  • 23:41needed to substantiate that.
  • 23:42And likely the causal mechanism
  • 23:44is due to making it easier
  • 23:46for patients to stay in care.
  • 23:48And I want to emphasize these results
  • 23:50because I think a lot of people here
  • 23:52know that there's been tremendous
  • 23:54national efforts and resources put in
  • 23:56to try to combat the overdose epidemic,
  • 23:58both from NIH,
  • 23:59but really kind of at the state
  • 24:00and federal level when it comes
  • 24:02to service provision.
  • 24:03And these data are some of the first to
  • 24:05indicate that a particular intervention
  • 24:07is actually associated with improved
  • 24:09outcomes among this patient population.
  • 24:11And so This is why it's particularly.
  • 24:13Promising.
  • 24:13There's actually very few things that
  • 24:15we can think about to really improve
  • 24:17outcomes in this patient population.
  • 24:21But I don't want to just stop there.
  • 24:24And so the although I've emphasized
  • 24:27I would say some of the potential
  • 24:30positive impacts from telehealth,
  • 24:32I I think that we also have to
  • 24:34emphasize that the this might not be
  • 24:35the same story for a lot of our other
  • 24:38patient populations including other
  • 24:39patients with substance use disorders.
  • 24:41So in a paper that's currently
  • 24:43under review by our team that's
  • 24:45led by Doctor Paramus Swami,
  • 24:47we examined treatment including
  • 24:49both medications and psychotherapy
  • 24:51among all patients with alcohol
  • 24:53use disorders in the VA.
  • 24:54And as you know,
  • 24:56unlike opioid use disorder
  • 24:57where medications aren't average
  • 24:58are the effective treatments
  • 25:00for alcohol use disorder,
  • 25:01both medication and psychotherapy are
  • 25:04effective in approximately similarly so.
  • 25:06So unfortunately,
  • 25:07what we found in this study is
  • 25:08that there was a dramatic drop in
  • 25:10alcohol use disorder treatment,
  • 25:12specifically in psychotherapy treatment
  • 25:13after the start of the pandemic,
  • 25:15which did not normalize one year after.
  • 25:19So in this figure you see we examine
  • 25:20trends in alcohol use disorder care.
  • 25:22So the entire population of veterans
  • 25:24with alcohol use disorder in the VA
  • 25:26receiving care one year pre to one
  • 25:28year post the start of the pandemic.
  • 25:30And what you see is that soon after
  • 25:32the start of the pandemic there was a
  • 25:34huge drop in in person visits but that
  • 25:36was not replaced fully by video and
  • 25:38in particular phone visits which is
  • 25:40what we saw for medications for OUD.
  • 25:42And in the study we actually found
  • 25:44the rates of medication treatment.
  • 25:45So now so our FDA approved
  • 25:48medications like naltrexone.
  • 25:49Increased during the study period.
  • 25:51But because medications are so
  • 25:52much less often used for alcohol
  • 25:54use disorder than psychotherapy,
  • 25:56the increase in medication did not
  • 25:58substantially change the overall
  • 25:59treatment rates for alcohol use disorder,
  • 26:01which fell about 30% after the
  • 26:03start of the pandemic.
  • 26:05And this is a huge increase when
  • 26:06you think about how prevalent AUD
  • 26:08is and how widespread the impacts
  • 26:10of untreated illness.
  • 26:11And I would say this data suggests
  • 26:13that although it was easy for
  • 26:14us to transition to telehealth
  • 26:15for medication treatment,
  • 26:17there may have been substantial
  • 26:18barriers for psychotherapy.
  • 26:20Which also includes both individual
  • 26:21and group psychotherapy.
  • 26:26So in addition to examining
  • 26:28treatment utilization,
  • 26:29I also want to emphasize the importance
  • 26:31of understanding patient experiences
  • 26:32especially with newer models of care.
  • 26:35In a recent study by our team,
  • 26:36we conducted a semi structured
  • 26:38qualitative interviews with over 30
  • 26:40patients with opioid and alcohol use
  • 26:42disorder to better understand the
  • 26:44patient experiences with telehealth.
  • 26:45And we found that experiences vary widely
  • 26:48and we're actually quite unpredictable
  • 26:50emphasizing that there is not just
  • 26:52A1 size fits all model that's needed.
  • 26:55An experience is really dependent on
  • 26:57patient preferences and what was the
  • 26:59actual feasible alternative for each
  • 27:01patient at each point in their care.
  • 27:03So patients overall described
  • 27:05some advantages to telehealth.
  • 27:07One.
  • 27:08An interesting one I wanted to
  • 27:09point out is that some people felt a
  • 27:12decreased feeling of stigma or shame
  • 27:13or being judged for their substance
  • 27:16use disorders when they were seeing
  • 27:17their clinicians remotely and not
  • 27:19having to wait in waiting rooms.
  • 27:21However,
  • 27:21they also noted numerous disadvantages,
  • 27:23including a decreased sense of connection.
  • 27:25Report at times.
  • 27:28And for some people,
  • 27:29and then also numerous ongoing
  • 27:31logistical barriers,
  • 27:32including unreliable Internet services,
  • 27:34limited resources in this
  • 27:37particular population.
  • 27:38So I think overall what we're learning
  • 27:40is that COVID created a really,
  • 27:42I think, bizarre,
  • 27:43interesting experiment that none
  • 27:44of us would have asked for.
  • 27:47But before,
  • 27:47COVID said in there was very
  • 27:49little experience with telehealth,
  • 27:51and that occurred only in early
  • 27:53adopter settings.
  • 27:54However, after the start of COVID,
  • 27:56there was also not much.
  • 27:57Voice,
  • 27:58it felt like there wasn't a
  • 28:00lot of choice for us both as
  • 28:02clinicians or as patients.
  • 28:04But in a world I would hope going forward,
  • 28:07I I hope that we can learn some
  • 28:09of these lessons and then think
  • 28:10about what are the actual options
  • 28:12we can offer to patients.
  • 28:13And hopefully that it could occur in
  • 28:15a hybrid setting where some patients
  • 28:17were really prioritizing for one
  • 28:18treatment modality versus another.
  • 28:20And we're also trying to consider
  • 28:21what are reasonable options that
  • 28:23we want to give our patients.
  • 28:27OK. So I've actually had the luck
  • 28:29and the opportunity to have this
  • 28:31type of talk or conversation with
  • 28:34quite a number of large clinician
  • 28:36audiences across clinicians with
  • 28:38different types of in in different
  • 28:40areas of substance abuse treatment,
  • 28:42substance use disorder treatment.
  • 28:43And it's clear that there are many questions
  • 28:46that clinicians are struggling with now.
  • 28:48So and many of them really are
  • 28:51not necessarily being guided by a
  • 28:53lot of the data, some of the data
  • 28:54that I just put this presented.
  • 28:56And I think what I hear most is that
  • 28:58clinicians experience tremendous
  • 28:59uncertainty about what they should do
  • 29:01or offer to their patients right now.
  • 29:04On the one hand,
  • 29:05some clinicians have seen their no
  • 29:06show rates really drop when they've
  • 29:08offered more flexible appointments,
  • 29:10including via phone or video,
  • 29:12but there's also discomfort.
  • 29:14Sometimes about talking taking
  • 29:15care of patients who we might
  • 29:18have never seen in person.
  • 29:19And that also brings up questions like
  • 29:21how important is the physical exam?
  • 29:23When should a physical exam be done?
  • 29:25How often?
  • 29:26There's also very little in the way
  • 29:28of guidelines to guide general opioid
  • 29:30or other substance use disorder care,
  • 29:32which is a similar challenge we
  • 29:34face in general mental healthcare.
  • 29:36Questions like how often and what's the
  • 29:39utility of your in toxicology screens
  • 29:41comes up in general addiction care,
  • 29:43but these questions are further
  • 29:44magnified and come up even more
  • 29:46often when it comes to telehealth.
  • 29:48And at the same time,
  • 29:49as the pandemic has evolved,
  • 29:50our clinics are evolving again and
  • 29:52there's a feeling that the goal
  • 29:54with a lot of things about the
  • 29:55pandemic is to return to quote.
  • 29:57Normal defined as what
  • 29:59things were like before.
  • 30:01However, some of us are asking,
  • 30:03you know what,
  • 30:03what does that actually mean
  • 30:05and may that actually disrupt
  • 30:06care for some of our patients.
  • 30:08And the hard part though is as things change,
  • 30:11it's hard to really have the data to
  • 30:14understand what should be happening
  • 30:16because we're not using data
  • 30:18necessarily to inform that process.
  • 30:20And lastly,
  • 30:22you know,
  • 30:23I think what I've emphasized are
  • 30:24going to be persistent challenges
  • 30:26for a lot of our patients is that
  • 30:28the logistical barriers around
  • 30:30technology will still persist.
  • 30:31One thing that I didn't mention before
  • 30:33is that in the VA we actually can
  • 30:36give free tablets to our veterans
  • 30:37who need it in order to help them
  • 30:39access a video delivered care.
  • 30:41This is what I believe is probably
  • 30:42one of the only healthcare systems
  • 30:44that we're doing this for.
  • 30:46We also have great technical
  • 30:48assistance for patients to help
  • 30:49them understand how to connect.
  • 30:51Yet despite all of these support services,
  • 30:53obviously we still see challenges
  • 30:55for patients and also disparities
  • 30:57in which patients are able to
  • 30:59use video services with a lot of
  • 31:01our addiction patients.
  • 31:02Only able to access phone based care.
  • 31:06And so at the same time as having all
  • 31:08of these clinically related questions,
  • 31:11I think this is a really interesting
  • 31:13challenge that we have pretty much
  • 31:15the same policy related questions
  • 31:17that are being asked simultaneously
  • 31:18and that are also very challenging.
  • 31:22And I just want to summarize some
  • 31:23of the debates that are happening
  • 31:25at the federal and the state level.
  • 31:26So a lot of us know that the public
  • 31:28health emergency exemption of the
  • 31:30Ryan Hate Act that allowed us to
  • 31:32treat patients with controlled
  • 31:33medications over video telehealth.
  • 31:35Without an initial in person
  • 31:37visit that will likely expire.
  • 31:38Obviously,
  • 31:39as the PHE for the pandemic expires,
  • 31:43there are other pH that we can use,
  • 31:45for example the overdose pH.
  • 31:48However,
  • 31:48that's not a permanent solution
  • 31:49and there needs to be a more
  • 31:52permanent decision on whether or
  • 31:53not an initial in person visit is
  • 31:55required for telehealth for patients
  • 31:57receiving control medications.
  • 31:58And even before COVID to help
  • 32:01support telehealth for OUD,
  • 32:02the support act of 2018 had required the DEA.
  • 32:06To define rules for a special
  • 32:08registration process for telehealth for
  • 32:09addiction care and to define what will
  • 32:11be allowed for those clinics who did that.
  • 32:13But the deadline has now passed
  • 32:16without further steps and I think
  • 32:18a lot of it has to do with this.
  • 32:21These challenges and this uncertainty
  • 32:23about what constitutes good quality
  • 32:25care and the pros and cons of using
  • 32:27telehealth that remain unanswered.
  • 32:29There are other federal
  • 32:30pathways outside of the DA.
  • 32:32For example,
  • 32:33Samsung last month updated
  • 32:35federal rules for OTP's,
  • 32:36or opioid treatment programs,
  • 32:37also known as methadone Clinics,
  • 32:39which has allowed methadone
  • 32:41clinics to continue to start
  • 32:43buprenorphine care via telehealth.
  • 32:44But I think most of us think that the
  • 32:46impacts of those policy changes are
  • 32:47limited because the vast majority of
  • 32:49you've been working here in this country.
  • 32:51Prescribed outside of Otps,
  • 32:52for example,
  • 32:53by those of us in office space settings.
  • 32:56And just as important to these federal
  • 32:59level questions about what's allowed
  • 33:01is also reimbursement questions.
  • 33:03So CMS has said that they're going to
  • 33:06extend telehealth reimbursement of phone
  • 33:07and video visits through the end of 2023,
  • 33:10but that obviously leaves a
  • 33:12lot of uncertainty about what
  • 33:13will happen in the future.
  • 33:15And lastly,
  • 33:15there's so much confusion around the
  • 33:17differences in changing state laws.
  • 33:19So bordering states like Ohio and
  • 33:21Michigan can have different policies
  • 33:23completely and as part of a group at the
  • 33:25American Society of Addiction Medicine.
  • 33:27We recently released a public
  • 33:28policy statement summarizing some
  • 33:30of these key policy questions,
  • 33:32and also provided some overall
  • 33:34recommendations for addiction care.
  • 33:36But again, to emphasize in part,
  • 33:38we do need more data to guide what
  • 33:40good policy should look like.
  • 33:41But in some ways,
  • 33:42these things are being debated
  • 33:43so actively and so quickly,
  • 33:45it's challenging to provide that data.
  • 33:49OK, so I've discussed the
  • 33:51background in prior literature and
  • 33:52what telehealth has looked like.
  • 33:54Now I want to focus a little bit on what I
  • 33:56hope telehealth looks like in the future.
  • 33:58One of the things that I've emphasized
  • 34:00is a real question for the field of
  • 34:02addiction is how do we increase care
  • 34:04at the same time as sustaining or
  • 34:06even improving the quality of care
  • 34:08when it helps to and that should
  • 34:10also help patients stay in care.
  • 34:12And the one of the biggest
  • 34:14worries that comes up,
  • 34:15especially from regulators like
  • 34:16the FDA is telehealth as another
  • 34:20innovative model could increase access,
  • 34:22but does it potentially
  • 34:24result in lower quality care?
  • 34:25I think this is a key question for
  • 34:27all of us to be thinking about.
  • 34:29But I want to remind us that it's
  • 34:30important to think about access
  • 34:32and quality as two separate
  • 34:33independent dimensions.
  • 34:34Because I would like to say that we
  • 34:36could have good quality in person care.
  • 34:37We could have poor quality in personal care,
  • 34:40including pill mills that existed
  • 34:43well before COVID.
  • 34:45And in parallel,
  • 34:46as the overdose epidemic evolves,
  • 34:48the way we deliver care for opioid
  • 34:49use disorder and other substance
  • 34:51use disorders is also evolving.
  • 34:52And the challenges that we need to
  • 34:54find a way to care for very large
  • 34:56complicated population who are primarily
  • 34:58using fentanyl and using multiple substances.
  • 35:01And this means we can't just discontinue
  • 35:03medication treatment just because
  • 35:04someone is using another substance.
  • 35:06And it also means that we have to evolve
  • 35:08the way we deliver all addiction care,
  • 35:09including both in person and telehealth.
  • 35:12For me, I think about telehealth
  • 35:14as part of a fairly flexible.
  • 35:16Model of care delivery
  • 35:17using multiple modalities.
  • 35:19For example,
  • 35:19for our current population of
  • 35:20patients who are primarily using
  • 35:22fentanyl as the induction or the
  • 35:24starting phase of medication
  • 35:25treatment can be more unpredictable.
  • 35:27So although we have newer
  • 35:28induction models for our patients,
  • 35:30there's a real utility I think in a
  • 35:32more flexible treatment model where I
  • 35:34can have you know our clinic staff or
  • 35:36myself give patients multiple phone calls,
  • 35:38especially during times of instability,
  • 35:40but then bring them back in person only
  • 35:42when we feel like they're needed and
  • 35:44using toxicology screens as part of a tool,
  • 35:46but not as.
  • 35:47The only tool we rely on when we
  • 35:50think about how patients are doing.
  • 35:52So as I've shown,
  • 35:53we're starting to have data from studies,
  • 35:56but I as I've also shown,
  • 35:58we need answers to some of these questions,
  • 36:00pragmatic clinical questions
  • 36:01at the same time.
  • 36:03And recently myself and a
  • 36:05colleague in addiction medicine,
  • 36:07physician from family
  • 36:08medicine Doctor Chris Frank,
  • 36:10we developed with support from the
  • 36:12provider clinical support System,
  • 36:14a toolkit geared towards helping
  • 36:16clinicians and policymakers
  • 36:17think about some of these issues.
  • 36:19This is really one example.
  • 36:21It's publicly available.
  • 36:22But what I'm hoping to highlight
  • 36:24is that for our field of academic,
  • 36:27you know,
  • 36:28addiction psychiatrists and faculty members.
  • 36:31This is an area where all this
  • 36:32at the same
  • 36:33time is gathering data.
  • 36:34We also have to be thinking about
  • 36:37helping our clinicians to deliver
  • 36:38the best quality care that they can.
  • 36:41So I know I'm running out of time,
  • 36:42so I'm going to go through
  • 36:43these a little bit faster.
  • 36:45So I think I've also alluded to the
  • 36:47fact that the future of telehealth,
  • 36:49I hope is not telehealth as
  • 36:51it looks like during COVID.
  • 36:52You know, zoom visits with our patients I
  • 36:55think are not rocket science whatsoever.
  • 36:57But we in particular,
  • 36:59I think we can't expect this form
  • 37:01of telehealth to actually increase
  • 37:02treatment and we're having data that's
  • 37:05starting to suggest that, right.
  • 37:06So the VA care that I mentioned
  • 37:08although overall number of patients
  • 37:09increased that was mostly due to.
  • 37:11Patients staying on treatment longer
  • 37:13and not more patients engaging in care.
  • 37:15I think what we need to do in order to
  • 37:17actually get more patients into care.
  • 37:19So to actually help and address
  • 37:21the needs of the 90% of patients
  • 37:22who are non treatment seeking,
  • 37:23not actually seeing addiction
  • 37:25physicians or clinicians like some of
  • 37:28us here is we actually need to think
  • 37:30about the changing the model that we
  • 37:32actually deliver and reach patients.
  • 37:34And so I want to highlight some of
  • 37:36our team's recent work in this.
  • 37:38The first example is a new model of
  • 37:41care that we have piloted called the
  • 37:43INREACH model we've designed this to be.
  • 37:45Implemented in healthcare systems
  • 37:47to proactively identify outreach,
  • 37:50help increase motivation for patients
  • 37:52seen in primary care settings and
  • 37:54then we actually offer them care,
  • 37:56more accessible care delivered
  • 37:57via telehealth.
  • 37:58So it's not just screening and
  • 38:00intervening to increase their motivation,
  • 38:01it's actually giving them care at the
  • 38:05same time and care that's flexible and
  • 38:08accessible and also patient oriented
  • 38:10when it comes to treatment goals and
  • 38:13we're currently studying this model in.
  • 38:15A are A1 funded by NIH AAA and this
  • 38:18is a study that I lead with a close
  • 38:21colleague of mine, Doctor Aaron Bonner,
  • 38:24a clinical psychologist.
  • 38:25And a separate funded trial by an I AAA,
  • 38:28we're taking it one step further
  • 38:30and testing different virtually
  • 38:31delivered interventions in this case
  • 38:33including a patient health portal.
  • 38:35So all of us have used patient health
  • 38:37portals to communicate with our PCP's
  • 38:39and we're really using the patient
  • 38:41health portal in a broader way.
  • 38:43We're actually delivering an intervention,
  • 38:45so a counseling intervention to
  • 38:46try to engage patients using the
  • 38:48patient health portal,
  • 38:49which we know the vast majority of our
  • 38:52patients in our health care systems use
  • 38:54and in a trial with the smart design.
  • 38:57We're really testing different combinations
  • 38:58of engagement and treatment strategies,
  • 39:00stepping up care only for patients who
  • 39:02are needed as an example of like another
  • 39:05kind of a future more innovative model
  • 39:08that really incorporates telehealth,
  • 39:10but not really telehealth
  • 39:11as we've seen it so far.
  • 39:14And lastly,
  • 39:14I'll highlight our most one
  • 39:15of our most recent studies and
  • 39:17this is the study that I Co
  • 39:19lead with Derek doctor, Laura Coughlin,
  • 39:21another clinical psychologist called My Best.
  • 39:24And in this study,
  • 39:25we're really focused on that group of
  • 39:27patients who are our most complex patients,
  • 39:29so patients using Poly substances,
  • 39:31including primarily opioids and stimulants.
  • 39:34And really in this study,
  • 39:35we're using novel methods.
  • 39:36So this is not a clinical trial,
  • 39:38it's a prospective cohort study.
  • 39:40We're trying to understand
  • 39:41their novel drivers,
  • 39:42motivators for why they use substances,
  • 39:45especially risky combinations,
  • 39:46but also why they seek care
  • 39:48in different forms of care.
  • 39:50And the goal of this is to
  • 39:53understand how where can we engage.
  • 39:55Patients who are traditionally not
  • 39:57engaged in care and using novel
  • 39:59behavioral economic constructs
  • 40:00to understand kind of when
  • 40:02patients might be more ready,
  • 40:03less ready,
  • 40:04what are the drivers of their
  • 40:06substance use versus their motivation
  • 40:07to engage in care in order to
  • 40:09inform future interventions that
  • 40:11can be really tailored and targeted
  • 40:13to where patients might be most
  • 40:14ready to engage in treatment?
  • 40:19So I think I've talked a lot about
  • 40:21the various forms of telehealth,
  • 40:23what telehealth looked like before,
  • 40:24what telehealth looks like currently,
  • 40:26and really highlighting all the current
  • 40:28challenges that need a lot of our
  • 40:31expertise in order to inform what hopefully
  • 40:33care will look like in the future.
  • 40:35I think without this work,
  • 40:37what I am afraid of is that care will
  • 40:39actually just go back to what it was
  • 40:41like before without taking advantage of
  • 40:43some of the lessons that we've learned.
  • 40:45Ultimately though, I think that.
  • 40:47What I like to emphasize,
  • 40:49it's not really just about telehealth or
  • 40:50it's not really about telehealth at all,
  • 40:52but really about how do we use telehealth
  • 40:54as a tool or really any tools in
  • 40:57order to try to reach and engage more
  • 40:59patients with substance use disorders,
  • 41:01untreated substance use disorder,
  • 41:03most of whom are obviously going
  • 41:05to be ambivalent about any care,
  • 41:07creating more accessible treatment
  • 41:08options so that we can actually reach
  • 41:12a patient population who are likely
  • 41:14suffering the burden of untreated
  • 41:16substance use disorders and the key.
  • 41:18The unique challenges that they face.
  • 41:21So I'm going to stop there.
  • 41:22I appreciate your time and I'm going
  • 41:24to turn it over actually to as many.
  • 41:26But I also want to say something
  • 41:28really brief about Doctor Moore.
  • 41:30I think Doctor Moore and I met maybe
  • 41:31five or six years ago at a triple AP.
  • 41:33And we've had, you know,
  • 41:36so many conversations at this point,
  • 41:37like philosophical conversations
  • 41:39about telehealth that before COVID
  • 41:41were very philosophical.
  • 41:43And suddenly, you know,
  • 41:44after the start of COVID,
  • 41:45they became not philosophical at all,
  • 41:47I would say.
  • 41:47And I would really highlight his
  • 41:49work as being very innovative.
  • 41:51Practical,
  • 41:51clinical thinking in terms of
  • 41:54how to address policy issues,
  • 41:56but actually how to overcome them and
  • 41:59care for really vulnerable populations.
  • 42:02Starting well before COVID too.
  • 42:04So I'll turn it over.
  • 42:06Thank
  • 42:06you, Allison. That was great.
  • 42:07Umm, David is going to do a brief overview
  • 42:10and then we'll have time for questions.
  • 42:11And there's actually one already in the
  • 42:13chat if you just wanted to take a look
  • 42:15at it. So I'm just going to do very brief.
  • 42:18For those of you who don't know David Moore,
  • 42:19he's one of our own faculty members.
  • 42:22He went to undergrad at
  • 42:24the University of Virginia,
  • 42:25got an MD and PhD from the
  • 42:27University of Pennsylvania.
  • 42:28Then he came to Yale to do his residency.
  • 42:30Those of you probably know him through
  • 42:32his different roles.
  • 42:33Then he was chief resident
  • 42:34in emergency medicine.
  • 42:36And then did a quality and safety fellowship
  • 42:38over here at the VA. He joined the
  • 42:40faculty in 2017. At the same time,
  • 42:42he became director of the Vision
  • 42:44One Telemental Health hub.
  • 42:45And then two years later,
  • 42:47he became director of the Vision
  • 42:49One Clinical Resource hub.
  • 42:51I just want to say that he was
  • 42:53essentially pushed into the deep end
  • 42:55when he joined the faculty here.
  • 42:57And lucky for us,
  • 42:58he was able to swim and navigate the
  • 43:00choppy waters of administration at the VA.
  • 43:02He's one of the few.
  • 43:03There are these clinical resource hubs
  • 43:04throughout the VA he's one of the few.
  • 43:06Psychiatrists, so it's what
  • 43:08started as a telemental health hub,
  • 43:10now became a telehealth hub
  • 43:12that includes primary care,
  • 43:13specialty care like cardiology.
  • 43:15So he has,
  • 43:16I want to echo what Allison said,
  • 43:17he has done sort of an amazing job
  • 43:19of building this from the ground up.
  • 43:21So he's just going to give us a
  • 43:23brief overview of that and then
  • 43:24we'll have some time for questions.
  • 43:25So David?
  • 43:29Thanks as mini and and and thanks
  • 43:32Allison I want to echo while I bring up.
  • 43:35My slides, here we go.
  • 43:39You know how great it's been working
  • 43:41with with Allison and just wanted to
  • 43:44check are my slides sharing right now?
  • 43:47Yes, yeah, they look good. And.
  • 43:55Another thing and I realized there we
  • 43:56are going to bring up, I advance her.
  • 43:59So I can. Move them forward.
  • 44:02This will be very brief and
  • 44:04what it will be is in. Oops.
  • 44:07There we go, an overview of some of the
  • 44:09efforts here via Connecticut and Yale.
  • 44:11And I can't say how thankful I am for
  • 44:15working with Allison over the last
  • 44:17several years starting at AAA P but.
  • 44:22Really a lot of the things that
  • 44:23I'm going to talk about here are
  • 44:25build on some of the foundations
  • 44:27that Allison and and folks like
  • 44:29Allison are are bringing to this
  • 44:31in both research and evaluation.
  • 44:33Also wanted to thank his meanie meanie
  • 44:37who really had the foresight of
  • 44:40bringing telehealth into the mental
  • 44:42health service line of a Connecticut
  • 44:45and has supported me and others at
  • 44:49a Connecticut doing this work so.
  • 44:51I have no conflicts of interest.
  • 44:54And very brief overview.
  • 44:55I'm probably going to skip a few
  • 44:57slides and I apologize for that just so
  • 44:59there's time for question and answer,
  • 45:01answer really the thing that I've
  • 45:03been focused on and others at via
  • 45:06Connecticut have been focused on.
  • 45:08Is this fundamental problem that
  • 45:10there is a mismatch between where?
  • 45:13People live and where often they're
  • 45:16providers live and that this is
  • 45:19really exacerbated in populations
  • 45:21that are most at risk.
  • 45:23Often I'll talk about rural health,
  • 45:26but this is it's not just a problem
  • 45:29of rurality that that there there
  • 45:31is a mismatch and it's something
  • 45:33that telehealth can overcome,
  • 45:35but it's not just telehealth.
  • 45:37So I direct the clinical resource
  • 45:39hub service line at a Connecticut
  • 45:41and it's really a team.
  • 45:43I'm a psychiatrist who's responsible
  • 45:46for medical providers and,
  • 45:48and really I rely on the great.
  • 45:52You know, the great teams at VA,
  • 45:54Connecticut and Yale School of Medicine.
  • 45:57I'm also going to mention something
  • 45:59called the National Mental Health
  • 46:02and Suicide Prevention ECHO.
  • 46:04It really,
  • 46:05that's focused if folks are familiar
  • 46:07with Project Echo on the idea that we
  • 46:09need to train people to use evidence
  • 46:12based practices and that's led by.
  • 46:14Folks like Alan Edens,
  • 46:16all this slide going over this.
  • 46:18And it's focused on on getting rural sites,
  • 46:21but non rural sites as well to
  • 46:23adopt evidence based practices.
  • 46:25And then I'm going to shift gears
  • 46:28just to highlight the national Tele
  • 46:30Nephrology hub and spoke network.
  • 46:32I think one thing that in mental
  • 46:35health is always good to remind
  • 46:37ourselves is that the patients we
  • 46:39work with are much more likely to
  • 46:41die and suffer and have morbidity
  • 46:44from medical conditions than the
  • 46:47general population.
  • 46:49Mental illnesses interact with and
  • 46:53exacerbate medical conditions and
  • 46:55that decrease access to medical
  • 46:57problems is going to be much worse
  • 47:00in the populations we work with.
  • 47:04I'm going to briefly put up this slide.
  • 47:07This is really a thank you slide
  • 47:09acknowledgement slide to a lot of
  • 47:11people in the clinical resource
  • 47:12hub doing substance use work.
  • 47:14The the nephrologist and evaluators
  • 47:16working in the hub and spoke
  • 47:19network and then the ECHO team.
  • 47:21And you'll see a lot of familiar faces here,
  • 47:24but for the sake of time,
  • 47:24I'm going to skip over it.
  • 47:26One other person I want to highlight here
  • 47:28who's not on this slide is Mark Rosen,
  • 47:30who directs the addiction psychiatrist
  • 47:32firm and a Connecticut I worked with.
  • 47:34The conduit,
  • 47:35which is a national implementation
  • 47:38facilitation grant that that
  • 47:39just wrapped up last year,
  • 47:41but he's continuing to study the
  • 47:44implementation of Tele buprenorphine and
  • 47:46really is a leader in this field and I'm
  • 47:50really thankful for his guidance and.
  • 47:53In support as we started our nephrol or our,
  • 47:56excuse me,
  • 47:57our buprenorphine hub.
  • 48:00Really briefly, this is a map
  • 48:02of the clinical resource hub and
  • 48:04what you'll notice is it began
  • 48:06as a mental health hub in blue.
  • 48:08These are the unique veterans
  • 48:10treated each quarter.
  • 48:11It's by fiscal year,
  • 48:12which is a little funny in the VA,
  • 48:13but I think the take away is that
  • 48:16mental health grew but so did primary
  • 48:18care and then specialty medicine
  • 48:20as well and then what and what this
  • 48:23really reflects is especially during
  • 48:25the pandemic that all aspects of care.
  • 48:29Umm experience decreased access,
  • 48:31both from provider turnover but
  • 48:34just from disruption of services.
  • 48:36And it's largely based at VA Connecticut.
  • 48:39And this is a an estimate of the
  • 48:43network of services that are provided
  • 48:46largely through video into the home,
  • 48:48but also video in the clinic,
  • 48:50which is that top graphic.
  • 48:54This is a high level
  • 48:56description of the services.
  • 48:57We call ourselves a hub
  • 48:59or really we're a network.
  • 49:01The majority of services come
  • 49:03from VA Connecticut and they're
  • 49:05supported by Yale faculty.
  • 49:06But we can see is we also bring in
  • 49:09a really high quality providers
  • 49:11from White River Junction, Vt,
  • 49:13Boston and Providence and and even
  • 49:15Maine which often receives our services.
  • 49:18We we we collaborate with
  • 49:20cardiologists up there,
  • 49:21we try to focus on foundational services.
  • 49:24Things like mental health,
  • 49:26primary care,
  • 49:26substance use and substance use,
  • 49:28excuse me,
  • 49:29and and pain and really substance
  • 49:31use is a foundational service in
  • 49:33the VA and and we've really built
  • 49:35that program out intentionally.
  • 49:37But we also really do make an effort
  • 49:39to make sure that there's good access
  • 49:42to specialty medical programs as well,
  • 49:44including renal, cardiology,
  • 49:46liver and surgical services.
  • 49:51Our our substance use team and
  • 49:52actually that I left two people off
  • 49:54accidentally and that was an intentional.
  • 49:56Kristen Serowik, a psychologist,
  • 49:58and Christine Lozano are
  • 49:59both on the Yale faculty.
  • 50:01They're part of this team right now.
  • 50:04I was going to highlight the prescribers
  • 50:07just because just because I think it
  • 50:10complements Doctor Lynn's talk and
  • 50:12and really what they're doing and and
  • 50:14what what the efforts in psychiatry
  • 50:17and prescribing has been has to
  • 50:19try to bring a virtual prescriber.
  • 50:22Into a local substance use team
  • 50:24that substance use care and most
  • 50:26and for especially for the most
  • 50:28complex patients really is inner
  • 50:30professional in both nursing,
  • 50:31social work therapy and schedulers.
  • 50:34And and there's a component of this
  • 50:36that has to be in person and over
  • 50:39the last several years since the
  • 50:41beginning of the pandemic we what
  • 50:43we saw was that there was enormous
  • 50:45turnover of prescribers in substance
  • 50:47use settings and that several sites
  • 50:50actually lost their prescribers.
  • 50:51So the Manchester NH.
  • 50:53System, a large clinic in Worcester,
  • 50:55MA and actually a residential
  • 50:57program in Bedford,
  • 50:58MA.
  • 50:58And so we set up clinics and over
  • 51:01the past two years we've been able
  • 51:04to work with about 400 veterans
  • 51:06and outpatient settings,
  • 51:08three hundreds of of those
  • 51:10receiving medications for opiate
  • 51:11use disorder from our prescribers.
  • 51:14And then about 200 veterans and residential
  • 51:16settings that had lost their prescribers.
  • 51:19And for the sake of time,
  • 51:21I'm going to advance kind of quickly,
  • 51:23but one of the key points is
  • 51:24I think that we do have done a
  • 51:26really good job and actually a
  • 51:28better job of getting people onto
  • 51:30medications for opiate use disorder.
  • 51:32Our prescribers are filling more
  • 51:34Narcan and there are also prescribing
  • 51:37more medications for alcohol use
  • 51:40disorder than the local VA's are
  • 51:42doing and one of the limitations.
  • 51:44Is that it probably needs more
  • 51:46nursing support since we don't
  • 51:47have people on the ground.
  • 51:48There are no addiction
  • 51:50psychiatrists at these sites.
  • 51:55I'm going to briefly touch on this idea that.
  • 51:59Complex care is interprofessional
  • 52:02again, and that if.
  • 52:05The VA's or communities or facilities
  • 52:07are going to implement complex care.
  • 52:10It actually requires a lot of training.
  • 52:13That things like ketamine as ketamine,
  • 52:15that are priorities to implement
  • 52:18at BA's across the country or
  • 52:21facilities across the country,
  • 52:22that they need to have training to do that
  • 52:24from people experienced with it at Yale,
  • 52:27we take that for granted.
  • 52:28So one of the things.
  • 52:31We've been working on in the National
  • 52:33mental health and suicide prevention ECHO
  • 52:34and I'm going to mention everyone involved,
  • 52:36Ellen Edens,
  • 52:37Gabriella Garcia Besado, Toral Surdi,
  • 52:40Brent Moore and Minoxidil Razia,
  • 52:44all on the faculty at Yale,
  • 52:45but also a host of other people have
  • 52:48been working at making practical
  • 52:51simulation based trainings and case based
  • 52:54trainings and really high priority.
  • 52:57Programs and some of this is kind of
  • 52:59case based interactive trainings and
  • 53:02what we call echoes and substance use
  • 53:05mental health and LGBTQ plus mental
  • 53:08health but also things that are more
  • 53:10intensive than interprofessional
  • 53:12focused on ketamine, esketamine,
  • 53:14substance use,
  • 53:15Co occurring liver and substance
  • 53:18use disorders and stimulants and
  • 53:21Co occurring cardiac toxicity and
  • 53:24from those stimulants and.
  • 53:27And and these programs are all
  • 53:30multi hour multiday trainings that
  • 53:33are focused on training providers
  • 53:35not just prescribers but the whole
  • 53:38team at a remote facilities who
  • 53:41don't have that expertise on site.
  • 53:45And then finally,
  • 53:46this is going to be very brief because I'm,
  • 53:48I think we're out of time is this is
  • 53:52actually a really important point is
  • 53:54that while there are you know people
  • 53:56struggle in substance use to get
  • 53:58treatments out and mental health in
  • 53:59general to the patients who need them,
  • 54:02mental health is really way ahead
  • 54:04of the game.
  • 54:05And that during the pandemic specialty
  • 54:07medicine had to really try to build
  • 54:10new programs that never existed.
  • 54:12We we had this in mental health
  • 54:14to a certain extent.
  • 54:15And one of the things that we tried
  • 54:18to do in our clinical resource hub
  • 54:20was get renal care out to veterans
  • 54:23nationally and I want to highlight
  • 54:24this map on the left and and then
  • 54:27I'm probably going to end because
  • 54:28what we did was we,
  • 54:30we we got a grant from the Office
  • 54:33of Rural Health to develop.
  • 54:36A network of nephrology hubs and it's based.
  • 54:40The first two were based at Boston and
  • 54:43Connecticut and went to highlight Ramon
  • 54:45Venezio and and Susan Crowley both.
  • 54:48So Susan Dr.
  • 54:49Crowley is based at Yale and is the
  • 54:51chief of the Nephrology program and
  • 54:54the National Kidney Disease lead and
  • 54:57and what what they've been doing
  • 54:58and we've been trying to figure
  • 55:00out is and when we wouldn't have
  • 55:02done without our initial work in
  • 55:04the treatment of opiate use.
  • 55:06Disorders because there are
  • 55:08actually large parallels in in
  • 55:10implementing complex services.
  • 55:13And what we learned in the
  • 55:15treatment of opioid use disorders
  • 55:16is really applied to renal disease.
  • 55:18And if you look at the map
  • 55:20map on the list, if, if,
  • 55:21if a VA is in the white or light green,
  • 55:25it really lacks access to renal care.
  • 55:28There's either no renal care or very
  • 55:30little renal care and not enough
  • 55:32for the population and it's the
  • 55:34rural sites and those rural sites.
  • 55:36No one had access in the community
  • 55:38and so this network and the and this
  • 55:41grant is focused on implementation.
  • 55:43It's it's a multi,
  • 55:44it's a 5 year program to expand the
  • 55:47Boston and nephrology hubs, but.
  • 55:52Grow new hubs and so. I want to skip
  • 55:56this slide just for the sake of time.
  • 55:59And it's going to be a multi site grant
  • 56:01and then over each year we're going
  • 56:03to add in new hubs starting on the
  • 56:06southeast and out West and and hopefully
  • 56:08develop a network of hubs of doing this.
  • 56:10And I think that's my last slide but you
  • 56:12know hopefully what folks take away is that.
  • 56:14Um at Yale and VA Connecticut
  • 56:16and the VA in general.
  • 56:21There there really has been a lot
  • 56:23of progress and effort and success,
  • 56:26but there is definitely a lot of
  • 56:28more work to do and all hit mute.
  • 56:30And I don't know if there's more questions
  • 56:33and I think we're about out of time.
  • 56:35Thank you, David.