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INFORMATION FOR

    Mehmet Sofuoglu, MD, PhD

    Professor of Psychiatry
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    Appointments

    Psychiatry
    Primary

    Additional Titles

    Director of VA New England Mental Illness Research, Education and Clinical Center (MIRECC)

    About

    Titles

    Professor of Psychiatry

    Director of VA New England Mental Illness Research, Education and Clinical Center (MIRECC)

    Appointments

    • Psychiatry

      Professor
      Primary

    Other Departments & Organizations

    • Cancer Prevention and Control
    • Center for Nicotine and Tobacco Use Research at Yale (CENTURY)
    • Division of Addictions
    • Psychiatry
    • Psychotherapy Development Center
    • Stress & Addiction Clinical Research Program
    • Yale Cancer Center
    • Yale Tobacco Center of Regulatory Science
    • Yale Translational Center to Develop Gender-Sensitive Treatment for Tobacco Dependence
    • Yale Ventures

    Education & Training

    PhD
    University of Minnesota (1991)
    MD
    Hacettepe University Faculty of Medicine (1986)

    Research

    Overview

    Our research is focused on development of novel treatments for substance use disorders and comorbid psychiatric disorders. We conduct both Phase 1 human laboratory studies and outpatient clinical trials testing the efficacy of potential treatments. We are also interested in tobacco regulatory science with a focus on the impact of nicotine and flavors on the appeal and abuse potential of tobacco products. We have developed a novel intravenous nicotine self-administration model which allows examination of both rewarding and aversive effects of nicotine in male and female smokers.
    Recent projects include:

    • The reinforcing threshold for intravenous nicotine self-administration in male and female smokers.
    • Individual factors influencing the rewarding effects of nicotine in male and female smokers.
    • Impact of menthol and other flavors on the rewarding effects of nicotine in humans.
    • The potential efficacy of cognitive enhancers as a treatment for substance use disorders.
    • Progesterone as a potential treatment to prevent relapse in women with substance use disorder.


    Medical Research Interests

    Cocaine-Related Disorders; Psychiatry; Psychiatry and Psychology; Psychotherapy; Substance-Related Disorders; Tobacco

    Research at a Glance

    Yale Co-Authors

    Frequent collaborators of Mehmet Sofuoglu's published research.

    Publications

    2024

    See All Publications

    Get In Touch

    Contacts

    Email
    Academic Office Number
    Mailing Address

    Psychiatry

    300 George St

    New Haven, CT 06511-

    United States

    Administrative Support