Matthew Grant, MD, FIDSA
Associate Professor of Medicine (Infectious Diseases)Cards
About
Research
Overview
Medical Research Interests
Candidiasis; Opportunistic Infections; Transplantation
Public Health Interests
Health Care Management
Publications
2024
Carbapenem-resistant Enterobacterales in solid organ transplant recipients
Boutzoukas A, Dai W, Cober E, Abbo L, Komarow L, Chen L, Hill C, Satlin M, Grant M, Fries B, Patel G, McCarty T, Arias C, Bonomo R, van Duin D, Investigators F, Kanj S, Jabbour J, Zhang F, Lok J, Salata R, Di Castelnuovo V, Gutierrez J, Cober E, Richter S, Anderson D, Evans B, Hill C, Cross H, Baum K, Arias R, Fowler V, Ordoñez K, Jacob J, Li L, Kreiswirth B, Manca C, Chen L, Desai S, Herc E, Cordova E, Rioseco M, Vichez S, Sanchez M, Valderrama S, Figueroa J, Arias C, Dinh A, Panesso D, Rydell K, Tran T, Hu F, Su J, Jiang J, Wang M, Xu X, Yang Y, Munita J, Spencer M, Alenazi T, Bonomo R, Marshall S, Rudin S, Huskins C, Kerry, Patel R, Schmidt-Malan S, Revolinski S, Wortmann G, Kalayjian R, Weston G, Ostrowsky B, Patel G, Eiras D, Kim A, Garcia-Diaz J, Salcedo S, Farrell J, Liu Z, Henderson A, Paterson D, Xie Q, Kaye K, Gao H, Yu Y, Waters M, Fries B, Eilertson B, Marimuthu K, Chew K, Smitasin N, Tambyah P, Gallagher J, Peleg A, Leroi M, Li L, Komarow L, Ge L, Evans S, McCarty T, Chambers H, Garner O, Abbo L, van Duin D, Lautenbach E, Han J, Doi Y, Wong D, Hanson B, Reyes J, Botero M, Diaz L, Perez F, Banerjee R, Dhar S, Satlin M, Zong Z. Carbapenem-resistant Enterobacterales in solid organ transplant recipients. American Journal Of Transplantation 2024 PMID: 39522694, DOI: 10.1016/j.ajt.2024.10.020.Peer-Reviewed Original ResearchSolid organ transplant recipientsCarbapenem-resistant EnterobacteralesOrgan transplant recipientsTransplant recipientsCohort studyAll-cause 30-day mortalityStabilized inverse probabilityMatched cohort studyCarbapenem resistanceMalignancy historyClinical isolatesAdmitted from homeMatched patientsTransplant historyInfection criteriaAll-causeInverse probabilityMortality riskEnterobacteralesMortalityOutcomesRecipientsMalignancyMulticenterTransplantation
2022
Dematiaceous fungal infections in solid organ transplantation: Systematic review and Bayesian meta‐analysis
Radcliffe C, Radcliffe AJ, Azar MM, Grant M. Dematiaceous fungal infections in solid organ transplantation: Systematic review and Bayesian meta‐analysis. Transplant Infectious Disease 2022, 24: e13819. PMID: 35253959, DOI: 10.1111/tid.13819.Peer-Reviewed Original ResearchConceptsSolid organ transplant recipientsDematiaceous fungal infectionSoft tissue infectionsFungal infectionsInfectious syndromesSystematic reviewEarly post-transplant periodCentral nervous system infectionCommon infectious syndromesPost-transplant periodNervous system infectionOrgan transplant recipientsSolid organ transplantationEnglish-language reportsInfection typeKidney recipientsLiver recipientsPediatric reportsTransplant recipientsPulmonary infectionSystem infectionTissue infectionsWorse prognosisDisseminated infectionMean ageSplenic Abscess in the New Millennium: A Descriptive, Retrospective Case Series
Radcliffe C, Tang Z, Gisriel SD, Grant M. Splenic Abscess in the New Millennium: A Descriptive, Retrospective Case Series. Open Forum Infectious Diseases 2022, 9: ofac085. PMID: 35299986, PMCID: PMC8923382, DOI: 10.1093/ofid/ofac085.Peer-Reviewed Original ResearchSplenic abscessHematogenous spreadAntimicrobial therapyLargest North American seriesHospital systemRetrospective case seriesNorth American seriesIndex hospitalizationImmunocompromised stateMedian durationClinical stabilityMedian agePercutaneous drainageCase seriesDiabetes mellitusProlonged hospitalizationRetrospective reviewMedian lengthRare infectionTreatment successHematological malignanciesPancreatic diseaseProbable casesInterventional radiologyAbscessA Difficult Microbiologic Diagnosis of Spontaneous Peritonitis
Palacios C, Grant M. A Difficult Microbiologic Diagnosis of Spontaneous Peritonitis. Infectious Diseases In Clinical Practice 2022, 30: e1124. DOI: 10.1097/ipc.0000000000001124.Peer-Reviewed Original ResearchPoor outcomes in both infection and colonization with carbapenem-resistant Enterobacterales
Howard-Anderson JR, Earley M, Komarow L, Abbo L, Anderson DJ, Gallagher JC, Grant M, Kim A, Bonomo RA, van Duin D, Muñoz-Price LS, Jacob JT. Poor outcomes in both infection and colonization with carbapenem-resistant Enterobacterales. Infection Control And Hospital Epidemiology 2022, 43: 1840-1846. PMID: 35105408, PMCID: PMC9343470, DOI: 10.1017/ice.2022.4.Peer-Reviewed Original ResearchConceptsCRE colonizationClinical outcomesCRE infectionsTract colonizationEpidemiology of patientsOutcomes of patientsProspective observational cohortCharacteristics of patientsOverall clinical outcomeShort-term acute care hospitalsUrinary tract colonizationCarbapenem-resistant EnterobacteralesRespiratory tract colonizationAcute care hospitalsDesirable clinical outcomesObservational cohortReadmission ratesSecondary outcomesPrimary outcomePoor outcomeUrinary tractRespiratory tractPatientsBetter outcomesClinical cultures
2021
Infectious Disease Images: A Remarkable, Free Resource
Radcliffe C, Grant M. Infectious Disease Images: A Remarkable, Free Resource. Open Forum Infectious Diseases 2021, 8: ofab560. PMID: 34888400, PMCID: PMC8651166, DOI: 10.1093/ofid/ofab560.Peer-Reviewed Original ResearchPott Disease: A Tale of Two Cases
Radcliffe C, Grant M. Pott Disease: A Tale of Two Cases. Pathogens 2021, 10: 1158. PMID: 34578190, PMCID: PMC8465804, DOI: 10.3390/pathogens10091158.Peer-Reviewed Case Reports and Technical NotesPott's diseaseBilateral iliopsoas abscessNew pleural effusionTuberculosis disease burdenIliopsoas abscessInfectious syndromesGreat masqueraderPleural effusionVertebral osteomyelitisHigh suspicionDisease burdenMental statusRemote historyClassic manifestationsOutpatient imagingExtensive destructionL3-L5TuberculosisDiseaseMenManagement recommendationsCase twoVasculitisAbscessOsteomyelitisBartonellosis in transplant recipients: A retrospective single center experience
Pischel L, Radcliffe C, Vilchez GA, Charifa A, Zhang XC, Grant M. Bartonellosis in transplant recipients: A retrospective single center experience. World Journal Of Transplantation 2021, 11: 244-253. PMID: 34164299, PMCID: PMC8218350, DOI: 10.5500/wjt.v11.i6.244.Peer-Reviewed Original ResearchStem cell transplant recipientsTransplant recipientsCell transplant recipientsClinical presentationDifferential diagnosisAutologous stem cell transplant recipientsHematopoietic stem cell transplant recipientsPost-transplant lymphoproliferative disorderRetrospective single-center experienceSingle-center retrospective studyRenal transplant recipientsSingle-center experienceCat-scratch diseaseCenter experienceClinical courseImmunocompromised hostLymphoproliferative disordersRetrospective studySingle institutionScratch diseaseSolid organsUnknown originDiagnostic testsRecipientsInfectionGenetic and Epidemiologic Analyses of an Outbreak of Pneumocystis jirovecii Pneumonia Among Kidney Transplant Recipients in the United States
Azar MM, Cohen E, Ma L, Cissé OH, Gan G, Deng Y, Belfield K, Asch W, Grant M, Gleeson S, Koff A, Gaston DC, Topal J, Curran S, Kulkarni S, Kovacs JA, Malinis M. Genetic and Epidemiologic Analyses of an Outbreak of Pneumocystis jirovecii Pneumonia Among Kidney Transplant Recipients in the United States. Clinical Infectious Diseases 2021, 74: 639-647. PMID: 34017984, PMCID: PMC9012955, DOI: 10.1093/cid/ciab474.Peer-Reviewed Original ResearchConceptsKidney transplant recipientsCases of PCPPneumocystis pneumoniaClinic visitsRisk factorsClinic exposureLow absolute lymphocyte countRisk of PCPAbsolute lymphocyte countFrequent clinic visitsPneumocystis jirovecii pneumoniaStrong risk factorNon-white raceCase-control analysisBelatacept groupMonthly infusionsTransplant recipientsBaseline characteristicsJirovecii pneumoniaLymphocyte countMultilocus sequence typingInterhuman transmissionRespiratory specimensUnivariate analysisEpidemiologic dataPyomyositis and Infectious Myositis: A Comprehensive, Single-Center Retrospective Study
Radcliffe C, Gisriel S, Niu YS, Peaper D, Delgado S, Grant M. Pyomyositis and Infectious Myositis: A Comprehensive, Single-Center Retrospective Study. Open Forum Infectious Diseases 2021, 8: ofab098. PMID: 33884279, PMCID: PMC8047863, DOI: 10.1093/ofid/ofab098.Peer-Reviewed Original ResearchInfectious myositisPercutaneous drainage proceduresRetrospective studyDrainage proceduresSingle-center retrospective studyThird of patientsTertiary care institutionTreatment success rateCases of pyomyositisSubjective feverMuscle painDiabetes mellitusAbscess formationCommon symptomsMedian lengthMean ageMental statusAntimicrobial therapyMost infectionsTreatment strategiesPyomyositisMyositisPathology specimensPatientsBacterial infections
Academic Achievements & Community Involvement
Clinical Care
Overview
Matthew Grant, MD, is an infectious diseases specialist who treats patients with vulnerable immune systems, such as those undergoing cancer treatment and transplants. When meeting new patients, he tells them, “We are in this together.”
An assistant professor of medicine (infectious diseases) at Yale School of Medicine, Dr. Grant says the challenge of managing unusual and complex infections in the current era of limited fungal diagnostic tools inspired him to study physician decision making in prescribing antifungal medications.
Clinical Specialties
Infectious Diseases; Heart Transplant Surgery
Fact Sheets
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Yale Medicine News
News
News
- March 15, 2024
Announcing the New Residents in the Yale-Waterbury Internal Medicine Residency Program!
- March 15, 2024
Announcing the Incoming Residents in the Internal Medicine Traditional Residency Program!
- March 17, 2023
New Residents in Internal Medicine's Traditional Residency Program
- December 12, 2022
Physician Associate Class of 2022 Celebrated at Commencement Ceremony
Get In Touch
Contacts
Locations
Yale Infectious Diseases
Academic Office
Laboratory for Medicine and Pediatrics (LMP)
15 York Street, Ste Rm 1085
New Haven, CT 06510
Patient Care Locations
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