Jason Lee, MD
Assistant ProfessorCards
About
Research
Overview
Medical Research Interests
Carcinoma, Renal Cell; Hematuria; Hydronephrosis; Kidney Calculi; Nephrolithiasis; Non-Muscle Invasive Bladder Neoplasms; Prostate; Prostatectomy; Transurethral Resection of Prostate; Ureteral Obstruction; Urinary Bladder Calculi; Urinary Bladder, Overactive; Urinary Bladder, Underactive; Urinary Retention
Publications
2023
Predicting Septic Shock After Emergent Ureteral Stenting in Stone-Related Obstruction and Presumed Infections
Lee J, Kottooran C, Hinojosa-Gonzalez D, Yaghoubian A, Uppaluri N, Hanson K, Borofsky M, Eisner B. Predicting Septic Shock After Emergent Ureteral Stenting in Stone-Related Obstruction and Presumed Infections. Journal Of Endourology 2023, 37: 127-132. PMID: 36136910, DOI: 10.1089/end.2022.0200.Peer-Reviewed Original ResearchConceptsUrinary tract infectionSeptic shockSIRS criteriaTract infectionsQuick Sequential Organ Failure Assessment (qSOFA) scoreSequential Organ Failure Assessment scoreSystemic inflammatory response syndrome criteriaConcomitant urinary tract infectionIntensive care unit admissionOrgan Failure Assessment scoreSequential Organ Failure AssessmentPostoperative septic shockCare unit admissionOrgan Failure AssessmentUnilateral ureteral obstructionUreteral stent placementPresumed infectionsVasopressor requirementUnit admissionPrimary endpointSyndrome criteriaConsecutive patientsRetrospective reviewUreteral obstructionStent placement
2022
Evaluation of fluid absorption during flexible ureteroscopy in an in vivo porcine model
Kottooran C, Twum‐Ampofo J, Lee J, Saunders J, Franco M, Budrewicz J, Eisner B. Evaluation of fluid absorption during flexible ureteroscopy in an in vivo porcine model. BJU International 2022, 131: 213-218. PMID: 35861056, PMCID: PMC10087161, DOI: 10.1111/bju.15858.Peer-Reviewed Original ResearchConceptsRenal pelvis pressurePressure-sensing guidewireIrrigation fluidFluid absorptionPorcine modelFlexible URSVivo porcine modelIrrigation fluid absorptionFemale Yorkshire pigsLive porcine modelURS proceduresVenous bloodMmHgRate of absorptionMean volumeFlexible ureteroscopyFURS proceduresPressure bagURSYorkshire pigsPorcine kidneyGuidewireInfusionKidneyUreteroscopyDiagnostic Flexible Ureteroscopy
Eisner B, Lee J, Kottooran C. Diagnostic Flexible Ureteroscopy. 2022, 223-234. DOI: 10.1007/978-981-19-2936-6_20.Peer-Reviewed Original ResearchDiabetes mellitus is associated with increased risk of positive qSOFA score but not with increased ICU admission in patients undergoing ureteral stent placement for ureteral stone and suspected infection
Lee J, Kottooran C, Hinojosa-González D, Yaghoubian A, Uppuluri N, Hanson K, Borofsky M, Eisner B. Diabetes mellitus is associated with increased risk of positive qSOFA score but not with increased ICU admission in patients undergoing ureteral stent placement for ureteral stone and suspected infection. Canadian Urological Association Journal 2022, 16: 430-434. PMID: 36656692, PMCID: PMC9851227, DOI: 10.5489/cuaj.7896.Peer-Reviewed Original ResearchUrinary tract infectionUreteral stent placementQuick Sequential Organ Failure AssessmentDevelopment of septic shockPostoperative septic shockObstructing ureteral stonesSeptic shockUreteral stonesDiabetes mellitusPositive qSOFA scoreIntensive care unitStent placementQSOFA scoreNon-DMIncreased riskMulticenter study of patientsSequential Organ Failure AssessmentSevere infectious complicationsInstitutional review board approvalAssociated with increased riskOrgan Failure AssessmentStudy of patientsReview board approvalRisk of septic shockIncreased ICU admissionMP44-08 A NOVEL SCORE TO PREDICT SEPSIS IN PATIENTS UNDERGOING URETERAL STENT PLACEMENT FOR OBSTRUCTING STONE AND PRESUMED URINARY TRACT INFECTION
Hinojosa-Gonzalez D, Lee J, Kottooran C, Yaghoubian A, Uppaluri N, Hanson K, Borofsky M, Eisner B. MP44-08 A NOVEL SCORE TO PREDICT SEPSIS IN PATIENTS UNDERGOING URETERAL STENT PLACEMENT FOR OBSTRUCTING STONE AND PRESUMED URINARY TRACT INFECTION. Journal Of Urology 2022, 207: e754. DOI: 10.1097/ju.0000000000002610.08.Peer-Reviewed Original Research
2021
MP18-05 CONCORDANCE BETWEEN BLADDER AND RENAL PELVIS URINE CULTURES IN PATIENTS WITH OBSTRUCTING URETERAL STONES AND SUSPECTED INFECTION
Kottooran C, Lee J, Yaghoubian A, Uppaluri N, Hanson K, Borofsky M, Eisner B. MP18-05 CONCORDANCE BETWEEN BLADDER AND RENAL PELVIS URINE CULTURES IN PATIENTS WITH OBSTRUCTING URETERAL STONES AND SUSPECTED INFECTION. Journal Of Urology 2021, 206: e318-e319. DOI: 10.1097/ju.0000000000002003.05.Peer-Reviewed Original ResearchPD26-09 USING THE QUICK SEQUENTIAL ORGAN FAILURE ASSESSMENT SCORE TO PREDICT SEPTIC SHOCK AFTER URETERAL STENTING FOR PATIENTS WITH URETERAL STONE AND PRESUMED URINARY TRACT INFECTION
Lee J, Kottooran C, Yaghoubian A, Uppaluri N, Hanson K, Borofsky M, Eisner B. PD26-09 USING THE QUICK SEQUENTIAL ORGAN FAILURE ASSESSMENT SCORE TO PREDICT SEPTIC SHOCK AFTER URETERAL STENTING FOR PATIENTS WITH URETERAL STONE AND PRESUMED URINARY TRACT INFECTION. Journal Of Urology 2021, 206: e440-e441. DOI: 10.1097/ju.0000000000002019.09.Peer-Reviewed Original ResearchFlat Panel Detector c-Arms Are Associated with Dramatically Reduced Radiation Exposure During Ureteroscopy and Produce Superior Images
Lee J, Venna A, McCarthy I, Cilento B, Demers M, MacDougall R, Beaulieu D, Nosrati R, Nelson C, Kurtz M. Flat Panel Detector c-Arms Are Associated with Dramatically Reduced Radiation Exposure During Ureteroscopy and Produce Superior Images. Journal Of Endourology 2021, 35: 789-794. PMID: 33528298, DOI: 10.1089/end.2020.0974.Peer-Reviewed Original Research
2019
Female underactive bladder – Current status and management
Yamany T, Elia M, Lee J, Singla A. Female underactive bladder – Current status and management. Indian Journal Of Urology 2019, 35: 18-24. PMID: 30692720, PMCID: PMC6334577, DOI: 10.4103/iju.iju_306_18.Peer-Reviewed Original ResearchUnderactive bladderManagement of UABSlow urinary streamLong-term care facilitiesClean intermittent catheterizationCommon clinical entityInternational Continence SocietyStem cell therapyIncomplete bladderIntermittent catheterizationStorage symptomsIdiopathic causesFemale patientsPathophysiologic mechanismsClinical entitySymptom improvementUrinary streamExact etiologyPrevalence increasesElderly womenSymptom complexDiagnostic criteriaCare facilitiesTherapeutic interventionsTherapeutic tool
2017
Utilization Trends and Short-term Outcomes of Robotic Versus Open Radical Cystectomy for Bladder Cancer
Pak J, Lee J, Bilal K, Finkelstein M, Palese M. Utilization Trends and Short-term Outcomes of Robotic Versus Open Radical Cystectomy for Bladder Cancer. Urology 2017, 103: 117-123. PMID: 28189553, DOI: 10.1016/j.urology.2016.10.067.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBlood Loss, SurgicalBlood TransfusionComparative Effectiveness ResearchCystectomyFemaleHumansLength of StayLymph Node ExcisionMaleMiddle AgedOutcome and Process Assessment, Health CarePostoperative ComplicationsRetrospective StudiesRobotic Surgical ProceduresUnited StatesUrinary Bladder NeoplasmsConceptsShort-term outcomesOpen radical cystectomyRadical cystectomyLength of stayBlood transfusionBladder cancerIndex stayInpatient complicationsUnderwent lymph node dissectionResearch Cooperative System databaseSimilar short-term outcomesUtilization trendsLymph node dissectionRobotic radical cystectomyNode dissectionConduit diversionHospital dischargeHospital volumeParenteral nutritionReadmission ratesPrimary outcomeProlonged lengthHospital chargesSurgical approachRobotic patients
Clinical Care
Overview
Jason Lee, MD is a general urologist with a special focus on treating benign prostate hyperplasia (BPH), a noncancerous enlargement of the prostate gland that commonly affects men as they age.
“It’s a noncancerous condition and around 60% of men over the age of 60 experience symptoms associated with BPH, such as a weak urinary stream, frequent or urgent urination, and sometimes bleeding,” Dr. Lee says. While open surgery has traditionally been the go-to approach for treating very large prostates, Dr. Lee offers minimally invasive procedures such as the holmium laser enucleation of the prostate (HoLEP) as well as robotic-assisted surgery to provide effective treatments with faster recovery times.
In addition to BPH, Dr. Lee also treats a range of other urologic conditions, including kidney stones, cancers of the urinary tract, urinary tract infections, and voiding dysfunction. He also offers specialized care for men’s health conditions such as erectile dysfunction and elevated PSA.
Dr. Lee’s approach to patient care is centered on establishing trust and ensuring patient comfort. "I want my patients to feel confident that I am here to help," he says. "I take the time to explain their symptoms, available treatments, and which options are best suited to their individual needs based on their symptoms and anatomy."
Dr. Lee is also involved with clinical research, with interests in BPH, bladder cancer genomics, and systemic urinary tract infections.
Clinical Specialties
Urology; Stone Disease
Fact Sheets
Enlarged Prostate (Benign Prostatic Hyperplasia)
Learn More on Yale MedicineUroLift
Learn More on Yale MedicineProstatic Artery Embolization
Learn More on Yale MedicineHolmium Laser Enucleation of the Prostate (HoLEP)
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