Jane Jane, PhD
Associate Research Scientist in PsychiatryCards
About
Research
Publications
2024
Cognitive processing therapy (CPT) versus individual drug counseling (IDC) for PTSD for veterans with opioid use disorder maintained on buprenorphine
Petrakis I, Meshberg‐Cohen S, Nich C, Kelly M, Claudio T, Jane J, Pisani E, Ralevski E. Cognitive processing therapy (CPT) versus individual drug counseling (IDC) for PTSD for veterans with opioid use disorder maintained on buprenorphine. American Journal On Addictions 2024, 33: 525-533. PMID: 38624259, DOI: 10.1111/ajad.13557.Peer-Reviewed Original ResearchCognitive processing therapyIndividual drug counselingPosttraumatic stress disorderOpioid use disorderSubstance use disordersDrug counselingProcessing therapyPTSD symptomsUse disorderCognitive processing therapy groupEvidence-based trauma-focused psychotherapiesSelf-reported PTSD symptomsPosttraumatic stress disorder symptomsPosttraumatic stress disorder treatmentRemission of PTSD symptomsPosttraumatic Stress Disorder ChecklistComorbid opioid use disorderTrauma-focused psychotherapyTrauma-focused treatmentRates of comorbidityTreatment group differencesPCL-5Stress disorderGroup differencesRandomized clinical trials
2023
Progesterone Attenuates the Stress Response in Individuals with Alcohol Dependence and Post-Traumatic Stress Disorder – A Pilot Study
Ralevski E, Newcomb J, Pisani E, DeNegre D, Peltier M, Jane J, Yoon G, Petrakis I. Progesterone Attenuates the Stress Response in Individuals with Alcohol Dependence and Post-Traumatic Stress Disorder – A Pilot Study. Journal Of Dual Diagnosis 2023, 20: 39-51. PMID: 38147491, PMCID: PMC11214330, DOI: 10.1080/15504263.2023.2294989.Peer-Reviewed Original ResearchAlcohol use disorderStress-induced cravingCognitive performanceNegative affectNeutral scriptsStress disorderPost-traumatic stress disorderComorbid alcohol use disorderTraumatic Stress DisorderMeasures of cravingCurrent alcohol use disorderPositive emotionsTrauma scriptsPhysiological measuresCravingStress-induced symptomsTest sessionsPTSDAnxietyAffectUse disordersLaboratory sessionsCocaine dependenceAlcohol dependenceIndividuals
2017
Mecamylamine treatment for alcohol dependence: a randomized controlled trial
Petrakis IL, Ralevski E, Gueorguieva R, O'Malley SS, Arias A, Sevarino KA, Jane JS, O'Brien E, Krystal JH. Mecamylamine treatment for alcohol dependence: a randomized controlled trial. Addiction 2017, 113: 6-14. PMID: 28710873, PMCID: PMC5725262, DOI: 10.1111/add.13943.Peer-Reviewed Original ResearchConceptsHeavy drinking daysDrinking daysAlcohol use disorderUse disordersAlcohol consumptionAlcohol dependenceDouble-blind clinical trialNicotinic acetylcholine receptor antagonistWeeks of treatmentAcetylcholine receptor antagonistCurrent alcohol dependenceSignificant differencesTreatment-seeking smokersMecamylamine treatmentPlacebo groupMonth 3Primary outcomeSmoking statusNicotine withdrawalReceptor antagonistNovel pharmacotherapiesClinical trialsManagement therapyMecamylamineTreatment groups
2015
Prazosin for Veterans with Posttraumatic Stress Disorder and Comorbid Alcohol Dependence: A Clinical Trial
Petrakis IL, Desai N, Gueorguieva R, Arias A, O'Brien E, Jane JS, Sevarino K, Southwick S, Ralevski E. Prazosin for Veterans with Posttraumatic Stress Disorder and Comorbid Alcohol Dependence: A Clinical Trial. Alcohol Clinical And Experimental Research 2015, 40: 178-186. PMID: 26683790, DOI: 10.1111/acer.12926.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderUse of prazosinSymptoms of PTSDComorbid alcohol dependenceAlcohol dependenceClinical trialsComorbid conditionsSleep disturbancesNoradrenergic dysregulationAlcohol consumptionStress disorderTreatment of PTSDPTSD symptomsHigh clinical importanceMedication groupPharmacologic optionsPromising medicationMedication effectsMAIN OUTCOMEEffective treatmentPrazosinComorbid disordersClinical importancePsychosocial functionClinical issues
2013
Mecamylamine for Treatment of People With Dual Diagnoses of Depression and Alcohol Dependence
Ralevski E, Jane J, O’Brien E, Edens E, Arnaout B, Kerfoot K, Keegan K, Weiner J, Russo M, Petrakis I. Mecamylamine for Treatment of People With Dual Diagnoses of Depression and Alcohol Dependence. Journal Of Dual Diagnosis 2013, 9: 301-310. DOI: 10.1080/15504263.2013.835163.Peer-Reviewed Original ResearchDepressive symptomsAlcohol dependenceDual diagnosisRates of smokingMain outcome variablesSymptoms of depressionTreatment of peopleTreatment trialsComorbid depressionMecamylamineSide effectsNonsmokersSmokingSymptomsOutcome variablesBest treatmentDrinking outcomesDepressionPlaceboSmokersFurther studiesSignificant differencesDiagnosisParticipantsTreatmentCharacteristics and drinking patterns of veterans with alcohol dependence with and without post-traumatic stress disorder
Fuehrlein B, Ralevski E, O'Brien E, Jane JS, Arias AJ, Petrakis IL. Characteristics and drinking patterns of veterans with alcohol dependence with and without post-traumatic stress disorder. Addictive Behaviors 2013, 39: 374-378. PMID: 24090619, DOI: 10.1016/j.addbeh.2013.08.026.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdrenergic alpha-AntagonistsAdultAgedAlcohol DrinkingAlcoholismComorbidityConnecticutDiagnosis, Dual (Psychiatry)FemaleHumansMaleMassachusettsMecamylamineMental DisordersMiddle AgedNicotinic AntagonistsPlacebosPrazosinPsychotropic DrugsSeverity of Illness IndexStress Disorders, Post-TraumaticSubstance-Related DisordersTreatment OutcomeVeteransYoung AdultConceptsPost-traumatic stress disorderCo-occurring illnessesAlcohol dependenceStress disorderCo-occurring alcohol dependenceDetailed drinking historiesDifferent treatment studiesMajor depressive episodeClinical treatment settingsHeavy drinking daysAlcohol use disorderPre-treatment characteristicsBaseline characteristicsDepressive episodePsychiatric symptomsUse disordersDrinking daysDomains of psychopathologyTreatment settingsDrinking historyTreatment studiesPsychopathological domainsPTSD groupPTSD symptomsMore days
2012
Treatment for Comorbid Borderline Personality Disorder and Alcohol Use Disorders: A Review of the Evidence and Future Recommendations
Gianoli MO, Jane JS, O'Brien E, Ralevski E. Treatment for Comorbid Borderline Personality Disorder and Alcohol Use Disorders: A Review of the Evidence and Future Recommendations. Experimental And Clinical Psychopharmacology 2012, 20: 333-344. PMID: 22686496, PMCID: PMC3697118, DOI: 10.1037/a0027999.Peer-Reviewed Original ResearchConceptsAlcohol use disorderBorderline personality disorderComorbid borderline personality disorderTreatment optionsSubstance use disordersUse disordersDual diagnosisBPD symptomsPersonality disorderPopulation of patientsSecond-generation antipsychoticsAlternative treatment optionPatterns of comorbiditySymptoms of BPDMedication optionsGeneration antipsychoticsPoor prognosisPharmacological treatmentSpecific psychotherapyRecent medicationAlcohol consumptionPatientsAlcohol cravingSymptomsDisorders
2011
Effects of Acamprosate on Cognition in a Treatment Study of Patients With Schizophrenia Spectrum Disorders and Comorbid Alcohol Dependence
Ralevski E, O'Brien E, Jane JS, Dean E, Dwan R, Petrakis I. Effects of Acamprosate on Cognition in a Treatment Study of Patients With Schizophrenia Spectrum Disorders and Comorbid Alcohol Dependence. The Journal Of Nervous And Mental Disease 2011, 199: 499-505. PMID: 21716064, DOI: 10.1097/nmd.0b013e3182214297.Peer-Reviewed Original ResearchConceptsCognitive functioningSchizophrenia spectrum disordersSpectrum disorderAlcohol dependenceComorbid alcohol dependencePsychotic symptomsSymptoms of psychosisCognitionEffects of acamprosateAlcohol useFunctioningTreatment studiesAlcohol reductionMemorySample of patientsAcamprosate treatmentGroup of patientsNegative effectsAlcohol consumptionDisordersAttentionSymptomsAcamprosatePatientsSchizophreniaTreatment With Acamprosate in Patients With Schizophrenia Spectrum Disorders and Comorbid Alcohol Dependence
Ralevski E, O’Brien E, Jane JS, Dwan R, Dean E, Edens E, Arnaout B, Keegan K, Drew S, Petrakis I. Treatment With Acamprosate in Patients With Schizophrenia Spectrum Disorders and Comorbid Alcohol Dependence. Journal Of Dual Diagnosis 2011, 7: 64-73. PMID: 26954912, DOI: 10.1080/15504263.2011.569440.Peer-Reviewed Original ResearchEfficacy of acamprosateAlcohol dependenceSchizophrenia spectrum disordersMedication treatmentComorbid schizophreniaSignificant group x time interactionGroup x time interactionComorbid alcohol dependenceAlcohol use disorderSymptoms of schizophreniaX time interactionAcamprosate groupComorbid conditionsTreatment trialsAbstinent patientsClinical trialsSpectrum disorderAcamprosateGeneral populationUse disordersPatientsSchizoaffective disorderPositive symptomsSchizophrenic symptomsConsecutive days
2007
Gender Bias in Diagnostic Criteria for Personality Disorders: An Item Response Theory Analysis
Jane J, Oltmanns T, South S, Turkheimer E. Gender Bias in Diagnostic Criteria for Personality Disorders: An Item Response Theory Analysis. Journal Of Psychopathology And Clinical Science 2007, 116: 166-175. PMID: 17324027, PMCID: PMC4372614, DOI: 10.1037/0021-843x.116.1.166.Peer-Reviewed Original Research
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